Association between glucagon-like peptide-1 agonists and risk of diabetic retinopathy: a disproportionality analysis using FDA adverse event reporting system data [0.03%]
基于FDA不良事件数据库的GLP-1受体激动剂与糖尿病视网膜病变的关联性分析
Harmanjit Singh,Navreet Kaur Natt,Dwividendra Kumar Nim
Harmanjit Singh
Background: Glucagon-like peptide-1 (GLP-1) agonists are commonly prescribed for type 2 diabetes mellitus (T2DM). Concerns have emerged regarding their potential link to diabetic retinopathy (DR). ...
Glucocorticoid therapy in classic congenital adrenal hyperplasia: traditional and new treatment paradigms [0.03%]
经典的先天性肾上腺皮质增生的糖皮质激素治疗：传统和新的治疗方法
Irina Bancos,Hyunwoo Kim,Henry K Cheng et al.
Irina Bancos et al.
Introduction: Classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (CAH) is a rare genetic condition characterized by cortisol deficiency and excess adrenal androgens. CAH treatment is a lifelong balanc...
Hypouricemic effect of sodium glucose transporter-2 inhibitors: a network meta-analysis and meta-regression of randomized clinical trials [0.03%]
钠葡萄糖协同转运蛋白2抑制剂的降尿酸作用：随机临床试验的网状Meta分析和meta回归分析
Kannan Sridharan,Maya Mohammed Osman Hussein Alkhidir
Kannan Sridharan
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are known for their cardiovascular benefits, but their impact on serum uric acid levels is not well understood. This study evaluates the hypouricemic effects...
Trends and projections of type 2 diabetes mellitus in South Asia: a three-decade analysis and forecast through 2031 using global burden of disease study (1990 - 2021) [0.03%]
基于全球疾病负担研究（1990-2021）的南亚地区二型糖尿病流行趋势及2031年前发病人数预测分析
Vijay Kumar,Quazi Syed Zahiruddin,Diptismita Jena et al.
Vijay Kumar et al.
Background: The rapid rise of non-communicable diseases, particularly type 2 diabetes mellitus (T2DM), poses a significant global public health challenge, with South Asia experiencing an increasingly severe burden. This s...
Juan Eduardo Quiroz-Aldave,Jacsel Suarez-Rojas,Elman Rolando Gamarra-Osorio et al.
Juan Eduardo Quiroz-Aldave et al.
Introduction: Endocrine paraneoplastic syndromes (ePNS) are caused by malignant cells that induce hormonal alterations unrelated to the tissue of origin of the neoplasm. The aim of this manuscript is to review the pathoph...
Pamela U Freda
Pamela U Freda
Introduction: Acromegaly is due in almost all cases to a GH-secreting pituitary tumor. GH and IGF-1 excesses lead to its multi-system clinical manifestations and comorbidities. Acromegaly is under-diagnosed and typically ...
Fertility preservation options at cancer diagnosis; classifying use and decision-making in the United States [0.03%]
美国癌症患者生育力保存治疗的分类及决策机制
Sarita Pathak,Paxton Voigt,Margot Bellon et al.
Sarita Pathak et al.
Introduction: Incidence rates for cancer among adolescent and young adults (AYA) have increased 30% since 1970. Declines in mortality underscore the importance of discussing fertility preservation (FP) options prior to re...
Associations between dose-response of serum creatinine and type 2 diabetes mellitus risk: consistent and robust evidence from a systematic review and meta-analysis [0.03%]
系统综述和meta分析一致且可靠的证据提示血清肌酐剂量反应关系与2型糖尿病风险的相关性
Vu Thi Minh Phuong,Vu Thi Quynh Chi,Nguyen Di Khanh et al.
Vu Thi Minh Phuong et al.
Background: Skeletal muscle is the key target of insulin action. Therefore, a reduction in skeletal muscle mass may trigger insulin resistance, a mechanism of diabetes. Creatinine is the only metabolite of creatine phosph...
Biomarkers of endothelial dysfunction and cytokine levels in hypothyroidism: a series of meta-analyses [0.03%]
甲状腺功能减退的内皮细胞功能障碍生物标志物和细胞因子水平：一系列meta分析研究
Emiliana María Torres,Mariana Lorena Tellechea
Emiliana María Torres
Background: Hypothyroidism (HT) is associated with different comorbidities comprising increased arterial stiffness and decreased flow-mediated dilatation. The exact pathological mechanism of endothelial activation and dys...
Systematic review and meta-analyses of adipokine levels in hypothyroidism: a role for retinol-binding protein 4 [0.03%]
系统性回顾和荟萃分析：甲状腺功能减退症的脂联素水平：视黄醇结合蛋白4的作用？
Emiliana Maria Torres,Mariana Lorena Tellechea
Emiliana Maria Torres
Background: Hypothyroidism (HT) is associated with numerous well-characterized comorbidities and established biomarkers for subclinical atherosclerosis which may lead to an elevated risk of cardiovascular disease; however...