Fabrizio Barbetti,Novella Rapini,Riccardo Schiaffini et al.
Fabrizio Barbetti et al.
Introduction: Monogenic diabetes, a form of diabetes mellitus, is caused by a mutation in a single gene and may account for 1-2% of all clinical forms of diabetes. To date, more than 40 loci have been associated with eith...
Marianna Martino,Nairus Aboud,Beatrice Lucchetti et al.
Marianna Martino et al.
Introduction: Endogenous Cushing's syndrome (CS) is a rare, multi-systemic condition resulting from chronic glucocorticoid excess sustained by a pituitary adenoma (Cushing's disease, CD), an adrenal adenoma or, less frequ...
A modern approach to glucose-lowering therapy in frail older people with type 2 diabetes mellitus [0.03%]
脆弱老年2型糖尿病患者的降糖治疗新策略
Ahmed H Abdelhafiz,Daniel Pennells,Alan J Sinclair
Ahmed H Abdelhafiz
Marina Paula Andres,Carolina Souza,Marina Villaescusa et al.
Marina Paula Andres et al.
Introduction: Endometriosis is a chronic inflammatory disease that affects approximately 10%-15% of women of childbearing age. Laparoscopic surgery is the preferred surgical approach. Recently, robotic surgery has been us...
Current concepts surrounding neonatal hormone therapy for boys with congenital hypogonadotropic hypogonadism [0.03%]
先天性低促性腺激素性腺功能减退症男孩的新生儿激素治疗的当前概念
Du Soon Swee,Richard Quinton
Du Soon Swee
Introduction: Congenital hypogonadotropic hypogonadism (CHH) is a genetic disorder of reproduction and development, characterized by deficient gonadotropin-releasing hormone (GnRH) secretion or action, affecting 1-in-4,00...
Risk assessment, diagnosis, and treatment of cancer treatment-related adrenal insufficiency [0.03%]
癌症治疗相关性肾上腺功能不全的风险评估、诊断和治疗
Annabelle G Hayes,R Louise Rushworth,David J Torpy
Annabelle G Hayes
Introduction: Adrenal insufficiency (AI) is an easily treatable, potentially life-threatening condition, which is increasingly recognized in malignancy. The recent introduction of immune checkpoint inhibitors, in particul...
Understanding the protective effects of SGLT2 inhibitors in type 2 diabetes patients with chronic kidney disease [0.03%]
理解SGLT2抑制剂在2型糖尿病合并慢性肾脏病患者中的保护作用
André J Scheen,Pierre Delanaye
André J Scheen
Introduction: Sodium-glucose co-transporter type 2 inhibitors (SGLT2is) were developed as glucose-lowering agents for the management of type 2 diabetes (T2D). Unexpectedly, they showed a significant reduction in hospitali...
Understanding the pathophysiologic pathways that underlie obesity and options for treatment [0.03%]
理解肥胖的发病机制及治疗选择
Rekha B Kumar,Gitanjali Srivastava,Tirissa J Reid et al.
Rekha B Kumar et al.
Introduction: Obesity is a chronic, multifactorial condition with devastating health consequences. It was thought that obesity could be controlled with discipline and lifestyle changes, but we now know that the underlying...
The associations between body fat distribution and bone mineral density in the Oxford Biobank: a cross sectional study [0.03%]
牛津生物库中身体脂肪分布与骨矿物密度关系的横断面研究
Catriona Hilton,Senthil K Vasan,Matt J Neville et al.
Catriona Hilton et al.
Background: Body composition is associated with bone mineral density (BMD), but the precise associations between body fat distribution and BMD remain unclear. The regional adipose tissue depots have different metabolic pr...
Association of serum C-reactive protein (CRP) and D-dimer concentration on the severity of COVID-19 cases with or without diabetes: a systematic review and meta-analysis [0.03%]
血清C反应蛋白(CRP)和D-二聚体浓度与是否患有糖尿病的COVID-19病例严重程度的关系：系统评价和荟萃分析
Hoimonti Debi,Zarin Tasnim Itu,Mohammad Tohidul Amin et al.
Hoimonti Debi et al.
Introduction: Coronavirus disease (COVID-19) is a highly contagious disease that poses major public health risks. Fewer studies link high CRP and D-dimer levels to severe COVID-19 infection. Therefore, this study investig...