Osteoporosis in chronic kidney disease: diagnostic dilemmas and therapeutic controversies [0.03%]
慢性肾脏病的骨质疏松：诊断难题与治疗争议
Sukanya Sakthivel,Marie Houmaa Vrist,Bente Langdahl et al.
Sukanya Sakthivel et al.
Introduction: Fracture risk is substantially increased in chronic kidney disease (CKD) and rises with declining kidney function. Skeletal fragility in CKD results from reduced bone mass, altered bone microarchitecture, an...
The evaluation of plozasiran for the treatment of familial chylomicronemia syndrome [0.03%]
评估polaquinomod治疗家族性高乳糜微粒血症综合征的效果
Shyann Hang,Robert A Hegele
Shyann Hang
Introduction: Familial chylomicronemia syndrome (FCS) is a rare autosomal recessive disorder marked by severe hypertriglyceridemia and characteristic clinical manifestations, particularly acute pancreatitis. Conventional ...
The intersection of education and health: schools as a catalyst for childhood obesity prevention [0.03%]
教育与健康的关系：学校作为防治儿童肥胖的催化剂
Thomas M Barber,Elizabeth V Niven,Peter Tymms
Thomas M Barber
Introduction: The traditional school environment places emphasis on educational outcomes. There is great potential to build on existing work to re-design a school of the future that conflates both educational and healthca...
Suvasini Lakshmanan,Matthew Budoff
Suvasini Lakshmanan
Introduction: Subclinical atherosclerosis measured by coronary artery calcium (CAC) and osteoporosis often co-exist as indolent 'silent' conditions, remain underdiagnosed and undertreated, and are associated with signific...
Oral GLP-1 receptor agonists for the treatment of obesity: ATTAINing metabolic benefits to find the OASIS [0.03%]
口服GLP-1受体激动剂治疗肥胖：ATTAIN研究代谢获益以期觅得OASIS疗法
Kyriaki Vafeidou,Theocharis Koufakis,Konstantinos Stavropoulos et al.
Kyriaki Vafeidou et al.
How to treat diabetes mellitus in the older patients: being risk averse versus being too progressive [0.03%]
老年糖尿病患者的治疗：谨记风险 vs 过于激进
Sandeep Singh,Jeske J Walgers,Suat Simsek et al.
Sandeep Singh et al.
Lukasz Dzialach,Przemyslaw Witek
Lukasz Dzialach
Introduction: Cushing syndrome (CS) is a complex endocrine disorder with multifactorial pathophysiology and diverse comorbidities. Long-term biochemical and clinical control of CS remains challenging. Osilodrostat, a pote...
Skin deep: dermatologic challenges in PCOS through the female lifespan [0.03%]
浅尝辄止：多囊卵巢综合征的女性全生命周期皮肤问题挑战
Seda Hanife Oğuz,Başak Yalici Armagan,Bulent Okan Yildiz
Seda Hanife Oğuz
Introduction: Polycystic ovary syndrome (PCOS) is a lifelong endocrine-metabolic condition with prominent dermatologic manifestations such as hirsutism, acne/seborrhea, and female pattern hair loss (FPHL), which are frequ...
Hossein Mirmiranpour,Thomas M Barber
Hossein Mirmiranpour
Introduction: Interlinkage between lipid and carbohydrate metabolism remains a key focus of research into the pathogenesis and novel management of obesity-related conditions like Type 2 Diabetes (T2DM), dyslipidaemia, and...
Dialysis meets devices: the use of automated insulin delivery in end stage kidney disease and haemodialysis [0.03%]
透析遇上设备：终末期肾病和血液透析中自动胰岛素输送系统的应用
Panagiotis Pavlou,Lalantha Leelarathna,Parizad Avari et al.
Panagiotis Pavlou et al.
Introduction: Diabetes management in end-stage kidney disease (ESKD) presents unique challenges due to perturbations in renal physiology. ESKD influences the pharmacokinetics of insulin and glucose metabolism, while hemod...