Management of sexual dysfunction in menopause: an update on evidence-based strategies [0.03%]
绝经过渡期女性性功能障碍的管理：基于证据的策略更新
Giorgia E Parrotta,Laura Cucinella,Rossella E Nappi
Giorgia E Parrotta
Introduction: Female sexual dysfunction (FSD) at menopause is a group of prevalent and multifactorial conditions that significantly impair quality of life and well-being. Hormonal decline, particularly estrogen and androg...
Advances of pharmacological therapies in lipodystrophy syndromes: current evidence and future directions [0.03%]
遗传性脂代谢障碍综合征的药物治疗进展：现有证据和未来方向
Ozge Besci,Merve Celik Guler,Maria Cristina Foss-Freitas et al.
Ozge Besci et al.
Introduction: Lipodystrophy syndromes are a heterogeneous group of rare disorders characterized by partial or generalized loss of adipose tissue, which may be either inherited or acquired. Loss of adipose tissue in typica...
Growth hormone treatment in adults with Prader-Willi syndrome: an update [0.03%]
普拉德-威利综合征成人患者生长激素治疗的最新研究进展
Graziano Grugni,Alessandro Sartorio
Graziano Grugni
Introduction: Prader-Willi syndrome (PWS) is a rare disorder caused by the lack of expression of paternal genes on chromosome 15q11.2-q13. The clinical picture of PWS is characterized by neonatal hypotonia, hyperphagia, o...
Theocharis Koufakis,Dimitrios Patoulias,Djordje S Popovic et al.
Theocharis Koufakis et al.
Introduction: Basal insulin has long served as a cornerstone in the management of type 2 diabetes. However, the emergence of glucose-lowering agents with cardiometabolic benefits - such as glucagon-like peptide 1 receptor...
Is metformin effective and safe during pregnancy in women with PCOS? An overview of reviews [0.03%]
metformin在PCOS孕妇中的有效性和安全性：综述类文章概述
Stefano Palomba,Giuseppe Seminara,Flavia Costanzi et al.
Stefano Palomba et al.
Introduction: Metformin is a metabolic drug widely used in women with polycystic ovary syndrome (PCOS). It is effective for improving metabolic pattern and fertility, alone or combined with other treatments. Sparse data s...
Mike Armour,Justin Sinclair,Callie Seaman et al.
Mike Armour et al.
Introduction: Endometriosis is a chronic inflammatory condition that affects around 1 in 7 women of reproductive age. Current medical treatments tend to be sub-optimal to manage the range of symptoms, with low levels of p...
Petur B Juliusson
Petur B Juliusson
Advances in the genetics of Paget's disease of bone: from pathophysiology, diagnosis to clinical implications [0.03%]
骨Paget病的遗传学研究进展：从发病机制、诊断到临床意义
Laëtitia Michou,Jacques P Brown
Laëtitia Michou
Introduction: Paget's Disease of Bone (PDB) is a chronic, late-onset skeletal disorder characterized by highly localized regions of increased bone resorption, accompanied by excessive and abnormal new bone formation. Cons...
Personalized medicine in acromegaly: insights from the ACROFAST clinical trial [0.03%]
肢端肥大症的个性化治疗——来自ACROFAST临床试验的启示
Marta Araujo-Castro,Betina Biagetti,Víctor Navas-Moreno et al.
Marta Araujo-Castro et al.
Introduction: Personalized medicine has gained importance in the management of acromegaly, driven by advances in tumor classification, molecular profiling, and imaging modalities. This approach leads to achieved biochemic...
Growth hormone deficiency in Cushing's syndrome: an update on diagnosis and management [0.03%]
库欣综合征中的生长激素缺乏：诊断和治疗的最新进展
Nicholas A Tritos
Nicholas A Tritos
Introduction: Endogenous Cushing's syndrome (CS) is associated with substantial morbidity and mortality. Patients in remission may experience many comorbidities, including growth hormone deficiency (GHD). ...