Pamela U Freda
Pamela U Freda
Introduction: Acromegaly is due in almost all cases to a GH-secreting pituitary tumor. GH and IGF-1 excesses lead to its multi-system clinical manifestations and comorbidities. Acromegaly is under-diagnosed and typically ...
Fertility preservation options at cancer diagnosis; classifying use and decision-making in the United States [0.03%]
美国癌症患者生育力保存治疗的分类及决策机制
Sarita Pathak,Paxton Voigt,Margot Bellon et al.
Sarita Pathak et al.
Introduction: Incidence rates for cancer among adolescent and young adults (AYA) have increased 30% since 1970. Declines in mortality underscore the importance of discussing fertility preservation (FP) options prior to re...
Associations between dose-response of serum creatinine and type 2 diabetes mellitus risk: consistent and robust evidence from a systematic review and meta-analysis [0.03%]
系统综述和meta分析一致且可靠的证据提示血清肌酐剂量反应关系与2型糖尿病风险的相关性
Vu Thi Minh Phuong,Vu Thi Quynh Chi,Nguyen Di Khanh et al.
Vu Thi Minh Phuong et al.
Background: Skeletal muscle is the key target of insulin action. Therefore, a reduction in skeletal muscle mass may trigger insulin resistance, a mechanism of diabetes. Creatinine is the only metabolite of creatine phosph...
Biomarkers of endothelial dysfunction and cytokine levels in hypothyroidism: a series of meta-analyses [0.03%]
甲状腺功能减退的内皮细胞功能障碍生物标志物和细胞因子水平：一系列meta分析研究
Emiliana María Torres,Mariana Lorena Tellechea
Emiliana María Torres
Background: Hypothyroidism (HT) is associated with different comorbidities comprising increased arterial stiffness and decreased flow-mediated dilatation. The exact pathological mechanism of endothelial activation and dys...
Systematic review and meta-analyses of adipokine levels in hypothyroidism: a role for retinol-binding protein 4 [0.03%]
系统性回顾和荟萃分析：甲状腺功能减退症的脂联素水平：视黄醇结合蛋白4的作用？
Emiliana Maria Torres,Mariana Lorena Tellechea
Emiliana Maria Torres
Background: Hypothyroidism (HT) is associated with numerous well-characterized comorbidities and established biomarkers for subclinical atherosclerosis which may lead to an elevated risk of cardiovascular disease; however...
Kanakamani Jeyaraman,Paola Concolino,Henrik Falhammar
Kanakamani Jeyaraman
Introduction: Adrenocortical tumors (ACTs) are frequently encountered in clinical practice. They vary in clinical and biological characteristics from nonfunctional to life threatening hormone excess, from benign to highly...
Reema Karasneh,Sayer Al-Azzam,Karem H Alzoubi et al.
Reema Karasneh et al.
Background: The current study sets out to develop and validate a robust machine-learning model utilizing electronic health records (EHR) to forecast the risk of hypoglycemia among ICU patients in Jordan. ...
The utility of a machine learning model in identifying people at high risk of type 2 diabetes mellitus [0.03%]
预测2型糖尿病的机器学习模型的有效性研究
Abdullah Alkattan,Abdullah Al-Zeer,Fahad Alsaawi et al.
Abdullah Alkattan et al.
Background: According to previous reports, very high percentages of individuals in Saudi Arabia are undiagnosed for type 2 diabetes mellitus (T2DM). Despite conducting several screening and awareness campaigns, these effo...
Is there a target value for time in tight range for individuals with type 1 diabetes on MDI? Data from masked CGM [0.03%]
每日多次胰岛素注射的1型糖尿病患者血糖在目标范围内的时长是多少？来自隐匿式CGM的数据
Takayuki Ohno,Daisuke Tsujino,Rimei Nishimura
Takayuki Ohno
Objective: Time in Tight Range (TITR), defined as the percentage of time within the glucose range of 70 to 140 mg/dL, is anticipated to be challenging to maintain without causing hypoglycemia, especially in individuals wi...
Tirzepatide: unveiling a new dawn in dual-targeted diabetes and obesity management [0.03%]
Tirzepatide：双重靶点糖尿病和肥胖症管理的新曙光
Syed Arman Rabbani,Mohamed El-Tanani,Ismail I Matalka et al.
Syed Arman Rabbani et al.
Introduction: Incretin-based therapies have emerged as effective treatments for type 2 diabetes (T2D) and obesity. However, not all patients achieve optimal outcomes with existing treatments, highlighting the need for mor...