Brandon Wang,Stanislovas S Jankauskas,Pasquale Mone et al.
Brandon Wang et al.
Introduction: Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by diastolic dysfunction, systemic comorbidities, and chronic low-grade inflammation. Emerging evidence suggests th...
Sequential immunotherapy for alopecia areata: phase-driven immune rebalancing [0.03%]
用于治疗斑秃的序贯免疫疗法：按阶段调整免疫平衡
Yetan Shi,Xiuzu Song
Yetan Shi
Introduction: Alopecia areata (AA) is an immune-mediated non-scarring alopecia characterized by T lymphocytes attacking hair follicles (HFs), which has a seriously harmful impact on physical and mental health. The challen...
Transglutaminase 2 in chronic inflammation and fibrosis - a potential novel therapy for stricturing Crohn's disease [0.03%]
转谷氨酰胺酶2在慢性炎症和纤维化中的作用及针对克罗恩病的潜在新型治疗手段
Jyotsna Chandra,Gail A West,Yan Wang et al.
Jyotsna Chandra et al.
Introduction: In inflammatory bowel diseases (IBD), human intestinal myofibroblasts (HIMF) gets activated due to chronic inflammation and start accumulating excessive extracellular matrix (ECM). ECM drives the significant...
New advances on the interaction between internal and external factors in the tumor microenvironment of solid tumors [0.03%]
实体瘤肿瘤微环境中内外因素相互作用的最新研究进展
Cong Zhang,Qian Sun
Cong Zhang
Introduction: The tumor microenvironment is a dynamic and balanced internal environment that accompanies the whole process of tumor development, invasion, and metastasis. Immune checkpoint therapy, chimeric antigen recept...
Piero Ruscitti,Francesco Caso,Antonio Vitale et al.
Piero Ruscitti et al.
Introduction: Familial Mediterranean Fever (FMF) is the most common monogenic autoinflammatory disease worldwide. In this work, we reviewed the clinical management of FMF in adults also considering the possible developmen...
TBXAS1 deficiency: a novel monogenic cause of chronic nonbacterial osteomyelitis responsive to cox inhibitors [0.03%]
TBXAS1缺陷：一种慢性非细菌性骨髓炎的单基因病因，对cox抑制剂有反应
Rabia Miray Kisla Ekinci,Serdar Ceylaner,Fatma Dereli Devrez et al.
Rabia Miray Kisla Ekinci et al.
Background: Chronic nonbacterial osteomyelitis (CNO) is an autoinflammatory bone disease characterized by sterile bone inflammation. While monogenic causes are rare and typically present with early-onset, distinct skin or...
An overview of how ultrasound can guide treatment for patients with rheumatoid and psoriatic arthritis [0.03%]
超声波在类风湿性关节炎和银屑病关节炎治疗中的应用概述
Giulia Cruciani,Biancamaria Pianese,Giacomo Cafaro et al.
Giulia Cruciani et al.
Introduction: The treatment of rheumatic diseases has dramatically changed thanks to the availability of novel drugs. Besides clinimetric indexes, there is the strong need of valid, rapid and sensitive-to-change, possibly...
Pepsin, trypsin, and MUC5B are independent risk factors for hearing impairment in patients with laryngopharyngeal reflux-related chronic secretory otitis media [0.03%]
胃食管反流相关慢性分泌性中耳炎患者中胃蛋白酶、胰蛋白酶及MUC5B独立增加听力损失风险
Ying Cao,Jibing Qiu,De Huai et al.
Ying Cao et al.
Objective: This study evaluated the potential diagnostic utility of pepsin, trypsin, and mucin 5B (MUC5B) in hearing impairment in patients with laryngopharyngeal reflux (LPR)-related chronic secretory OM (CSOM). ...
Unveiling a spondyloarthritis-like phenotype in Sjögren's disease : clinical, serological, and radiological correlates of sacroiliitis in a real-world cohort [0.03%]
原发性干燥综合征中重叠的脊柱关节病表型：真实世界队列中腮腺炎的临床、自身免疫和影像学相关因素分析
Umut Bakay,Gülcan Gürer,Nedim Kaban et al.
Umut Bakay et al.
Background: Sjögren's Disease (SjD) primarily affects exocrine glands, but some patients develop axial manifestations. This study investigated the prevalence and predictors of sacroiliitis in primary SjD and proposed a c...
Regulatory T cell plasticity and immune deviation toward autoinflammation in HTLV-1-associated diseases: insights and implications [0.03%]
人疱疹病毒八型相关疾病中调节性T细胞的可塑性和免疫偏离向自炎症的发展：见解与影响
Mohammadreza Shafiei,Nastaran Ardalan,Arash Letafati et al.
Mohammadreza Shafiei et al.
Introduction: Human T-lymphotropic virus type-1 (HTLV-1) is a retrovirus associated with the development of various diseases. HTLV-1 contributes to the development of several disorders that mimic autoinflammation. The pat...