Lamotrigine and other therapy-associated HLH syndromes: a review [0.03%]
拉莫三嗪和其他与治疗相关的噬血细胞性淋巴组织细胞增多症综合征:综述评论
Yaswanta K Gummadi,Ashley Sutherland,Steven Rowe et al.
Yaswanta K Gummadi et al.
Introduction: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation that can occur secondary to medical interventions including immunomodulatory therapies such as immune checkpoint inhibit...
IL-17 at the eye - joint interface in psoriatic disease: mechanisms, clinical correlates, and therapeutic implications [0.03%]
银屑病中的眼部-关节界面的IL-17:机制、临床相关性和治疗意义
Mario Troisi,Salvatore Troisi,Luisa Costa et al.
Mario Troisi et al.
Introduction: Psoriatic arthritis (PsA) is an immune-mediated inflammatory disease in which the IL-23/Th17/IL-17 axis contributes to musculoskeletal and extra-musculoskeletal inflammation. Ocular manifestations, particula...
Our understanding of the interactions between immune cells and beta cells in the pancreas: autoimmune mechanisms leading to type 1 diabetes [0.03%]
我们对胰腺免疫细胞和β细胞之间相互作用的理解:导致1型糖尿病的自身免疫机制
Matthias von Herrath,Joana R N Lemos,Filip Krag Knop
Matthias von Herrath
Introduction: Type 1 diabetes (T1D) has long been viewed as an immune-driven disease characterized by the destruction of otherwise healthy pancreatic beta cells. However, growing evidence indicates that beta cells may act...
Svetlana P Eckert,Gabriela Funez-DePagnier,Mark D Hicar et al.
Svetlana P Eckert et al.
Introduction: The link between the risk of developing Multiple Sclerosis (MS) and Epstein-Barr Virus (EBV) infection has been confirmed. However, the mechanisms by which EBV influences MS remain unclear, likely due to the...
Ustekinumab for the treatment of psoriasis: a well-established therapy primed for resurgence [0.03%]
乌司奴单抗治疗银屑病:一种成熟疗法即将卷土重来
Omar Raheel,Alexander Uche,Pauline Do et al.
Omar Raheel et al.
Introduction: Ustekinumab has been an approved biologic therapy for moderate-to-severe psoriasis for over 16 years. With the emergence of newer IL-17 and IL-23 inhibitors, its use was largely supplanted by these more effe...
Recognizing and treating serious allergic reactions (anaphylaxis) in infants and toddlers: a plain language review [0.03%]
婴儿和幼儿严重过敏反应(过敏性休克)的识别与处理:简易语言解读.review
Michael Pistiner,Ari Cohen,Sanaz Eftekhari et al.
Michael Pistiner et al.
Giulia Vittori,Ivan Taietti,Riccardo Castagnoli
Giulia Vittori
Hair follicles as immune targets: unraveling cellular players, cytokine crosstalk, and precision pathways for future therapy of alopecia areata [0.03%]
毛囊作为免疫靶点:阐明细胞组成、细胞因子相互作用及精准治疗路径以应对斑秃
Kimia Heidari,Seyedshayan Shojaei,Arash Azari Matin et al.
Kimia Heidari et al.
Introduction: Alopecia areata (AA) is a relapsing autoimmune disorder caused by the collapse of anagen hair-follicle immune privilege, leading to targeted cytotoxic injury of the hair bulb. Its clinical heterogeneity refl...
Cofactor functions of magnesium in complement activation and antimicrobial responses [0.03%]
镁离子在补体活化和抗菌反应中的辅因子功能
Md S Zaman,Mainul Haque,Mohammed S Razzaque
Md S Zaman
Mast cell activation disorders: mechanisms, comorbidities and look alike [0.03%]
mast细胞活化障碍:机制、共病及类似症状
Theoharis C Theoharides,Duraisamy Kempuraj,Anne Maitland
Theoharis C Theoharides
Introduction: Mast Cells (MCs) are unique tissue immune cells found perivascularly close to nerves at interfaces with the external environment. Upon detection of danger signals, MCs act as master responders aiming to rest...