Mikhail Protopopov,Denis Poddubnyy
Mikhail Protopopov
Non-radiographic axial spondyloarthritis (nr-axSpA) represents a subtype of axial spondyloarthritis (axSpA) with no significant structural damage in sacroiliac joints and spine. In addition, patients with nr-axSpA demonstrate a substantial ...
Gabriella Moroni,Claudio Ponticelli
Gabriella Moroni
In the last few decades, identification of predictors of pregnancy outcome and appropriate pregnancy planning have significantly reduced the maternal and fetal risks in pregnant women with lupus nephritis. Areas covered: Successful pregnanc...
Paul J Deziel,Raymund Razonable
Paul J Deziel
Solid organ transplant (SOT) recipients are at high risk of opportunistic infections due to bacterial, viral, fungal, and parasitic pathogens. Anti-infective prophylaxis is a time-tested proven strategy for the prevention of these infection...
Advagraf® with or without an induction therapy for de novo kidney-transplant recipients [0.03%]
Advagraf？单药或联合诱导疗法在肾移植受者的维持治疗中的应用
Johan Noble,Thomas Jouve,Lionel Rostaing et al.
Johan Noble et al.
Cornerstone immunosuppressive therapy currently relies on immediate-release tacrolimus, a calcineurin inhibitor (CNI) that is potentially nephrotoxic and is more diabetogenic than cyclosporine A. Two new formulations of tacrolimus have been...
Icatibant for the treatment of hereditary angioedema with C1-inhibitor deficiency in adolescents and in children aged over 2 years [0.03%]
依替巴肽治疗十二岁及以上儿童和青少年C1酯酶抑制剂缺乏症遗传性血管水肿
Henriette Farkas,Kinga Viktória Kőhalmi
Henriette Farkas
Hereditary angioedema (HAE) due to C1-inhibitor deficiency (C1-INH-HAE) is a rare disorder with life-threatening complications if untreated. It begins during childhood, and reduces the patient's quality of life. Therefore, the availability ...
The role of imaging in early diagnosis and prevention of joint damage in inflammatory arthritis [0.03%]
影像学在炎性关节炎早期诊断和防治关节损害中的作用
Jiang Yue,Dongze Wu,Lai-Shan Tam
Jiang Yue
Inflammatory arthritis is characterized by chronic inflammation in the synovium, associated with degradation of cartilage and erosion of juxta-articular bone. The bone loss and joint destruction mediated by aberrant immunological responses ...
Microparticles - culprits in the pathogenesis of systemic lupus erythematosus? [0.03%]
微粒在系统性红斑狼疮发病机制中的作用不容小觑？
Niclas Stefan Rasmussen,Søren Jacobsen
Niclas Stefan Rasmussen
Cameron B Speyer,Karen H Costenbader
Cameron B Speyer
Systemic lupus erythematosus (SLE) is a multi-system inflammatory autoimmune disease of incompletely understood etiology. It is thought that environmental exposures 'trigger' or accelerate the disease in genetically-predisposed individuals....
Wolf-Henning Boehncke,Nicolo Costantino Brembilla
Wolf-Henning Boehncke
Antibodies or fusion proteins termed biologics allow the targeted therapy of diseases. Many of these agents have proven superior efficacy and safety to conventional therapies, and subsequently revolutionized the management of numerous chron...
Tania Gudu,Laure Gossec
Tania Gudu
Psoriatic arthritis (PsA) is a multi-organ chronic inflammatory disease which impacts patients both physically and psychologically. The highest priority for patients goes to pain relief, but also to ability to function and participate in so...