Julio Aires,Marie-José Butel
Julio Aires
The various bacterial communities associated with humans have many functions and the gut microbiota has a major role in the host. Bacterial imbalance in the gut, known as dysbiosis, has therefore been linked to several diseases. Probiotics,...
Lipid rafts: signaling and sorting platforms of cells and their roles in cancer [0.03%]
脂筏：细胞的信号转导和分选平台及其在癌症中的作用
Simon Staubach,Franz-Georg Hanisch
Simon Staubach
Lipid rafts are defined as microdomains within the lipid bilayer of cellular membranes that assemble subsets of transmembrane or glycosylphosphatidylinisotol-anchored proteins and lipids (cholesterol and sphingolipids) and experimentally re...
Cardiac proteomic responses to ischemia-reperfusion injury and ischemic preconditioning [0.03%]
心肌缺血再灌注损伤和缺血前适应的蛋白质组学反应
Hyoung Kyu Kim,Vu Thi Thu,Hye-Jin Heo et al.
Hyoung Kyu Kim et al.
Cardiac ischemia and ischemia-reperfusion (I/R) injury are major contributors to morbidity and mortality worldwide. Pathological mechanisms of I/R and the physiological mechanisms of ischemic preconditioning (IPC), which is an effective car...
Proteomics unravels the exportability of mitochondrial respiratory chains [0.03%]
蛋白质组学揭示线粒体呼吸链的出口能力
Isabella Panfoli,Silvia Ravera,Maurizio Bruschi et al.
Isabella Panfoli et al.
Expression of F1Fo-ATP synthase, which generates the majority of cellular ATP and is believed to be strictly confined to mitochondria, has recently been identified in ectopic locations, together with the four complexes of oxidative phosphor...
Choon-Sik Park,Taiyoun Rhim
Choon-Sik Park
Bronchial asthma is caused by allergic airway inflammation, resulting in reversible airway obstruction, characterized by airway hyper-responsiveness, bronchoconstriction, increased mucus secretion and an increase in lung vessel permeability...
Joern Barth,Walter Volknandt
Joern Barth
Synaptic vesicles are key organelles in chemical signal transmission allowing neurons to communicate with each other and neighboring cells. The numerous tasks of synaptic vesicles are governed by a unique set of proteins. Recently, proteomi...
Understanding and optimizing electrospray ionization techniques for proteomic analysis [0.03%]
用于蛋白质组分析的电喷雾离子化技术的理解与优化
Peter Liuni,Derek J Wilson
Peter Liuni
Electrospray ionization (ESI) mass spectrometry is a powerful and versatile tool for proteomic analysis. By understanding how proteins and peptides behave during ESI, it is possible to predict source conditions that will maximize ionization...
Bioinformatics approaches in the discovery and understanding of reproduction-related biomarkers [0.03%]
生物信息学方法在生殖相关生物标志物发现及作用机制阐释中的应用研究进展
Athanasios K Anagnostopoulos,Georgia Tsiliki,George Spyrou et al.
Athanasios K Anagnostopoulos et al.
The emerging field of bioinformatics in proteomics is introducing new algorithms in order to handle large and heterogeneous datasets and improve the knowledge-discovery process. Management systems, software construction and application, dat...
Proteomic analysis of amniotic fluid for the diagnosis of fetal aneuploidies [0.03%]
羊水蛋白质组分析在胎儿染色体非整倍体诊断中的应用研究
Aggeliki Kolialexi,Georgia Tounta,Ariadni Mavrou et al.
Aggeliki Kolialexi et al.
Advances in technologies associated with mass spectrometry-based proteomic techniques have added a new dimension to the field of biomedical research. Most of the existing research on human gestation has focused on the application of these h...
Enrique Calvo,Emilio Camafeita,Benjamín Fernández-Gutiérrez et al.
Enrique Calvo et al.
Selected reaction monitoring (SRM) is a highly selective and sensitive mass spectrometric methodology for precise and accurate quantification of low-abundant proteins in complex mixtures and for characterization of modified peptides, and co...