Amaya Albalat,Harald Mischak,William Mullen
Amaya Albalat
The technology platforms for proteome analysis have advanced considerably over the last few years. Driven by these advancements in technology, the number of studies on the analysis of the proteome/peptidome, with the aim of defining clinica...
Proteomics at the interface of psychology, gut physiology and dysfunction: an underexploited approach that deserves expansion [0.03%]
心理学、肠道生理和肠功能障碍之间的蛋白质组学：一个有待开发的领域
Luísa V Lopes,Martin Kussmann
Luísa V Lopes
Gut functions such as digestion and absorption are essential to life and the emerging insights into the gut-brain axis - that is, the cross talk between the enteric and CNS - point towards critical links between (eating) behavior, psycholog...
Recent advances in single-cell MALDI mass spectrometry imaging and potential clinical impact [0.03%]
近期单细胞基质辅助激光解析电离质量分析成像研究进展及其潜在临床影响
Kristin J Boggio,Emmanuel Obasuyi,Ken Sugino et al.
Kristin J Boggio et al.
Single-cell analysis is gaining popularity in the field of mass spectrometry as a method for analyzing protein and peptide content in cells. The spatial resolution of MALDI mass spectrometry (MS) imaging is by a large extent limited by the ...
Autoantibodies in cancer: prognostic biomarkers and immune activation [0.03%]
自身抗体在癌症中的作用：预后生物标志物和免疫激活
Kerstin Järås,Karen Anderson
Kerstin Järås
The development of proteomic technologies that display a wide variety of antigenic structures has led to the identification of autoantibodies to cancer-derived tumor antigens. These autoantibodies have been detected in sera from patients wi...
Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches [0.03%]
靶向蛋白质组方法弥合了蛋白质组学与假设驱动的蛋白质分析方法之间的差距
Ronald J Hause,Hyung-Do Kim,Kin K Leung et al.
Ronald J Hause et al.
While proteomic methods have illuminated many areas of biological protein space, many fundamental questions remain with regard to systems-level relationships between mRNAs, proteins and cell behaviors. While mass spectrometric methods offer...
Kenneth Fuh
Kenneth Fuh
The market for therapeutic proteins is on the rise, plagued by several challenges related to production amounts and costs. Solutions to these problems are widely thought to come from academia, governments and production companies. This conf...
Can a simple proteomics urine test assist in the early diagnosis of early-stage cancer? [0.03%]
简单的蛋白质组尿检能否协助早期癌症的诊断？
Holger Husi,Kenneth C Fearon,James A Ross
Holger Husi
Differential proteomics in the search for biomarkers of radiotherapy resistance [0.03%]
差异蛋白质组学在放射疗法抗性生物标志物研究中的应用
Lucy Scaife,Victoria C Hodgkinson,Philip J Drew et al.
Lucy Scaife et al.
The individualization of radiotherapy treatment would be beneficial for cancer patients; however, there are no predictive biomarkers of radiotherapy resistance in routine clinical use. This article describes the body of work in this field w...
Hao Hu,Cao Deng,Tao Yang et al.
Hao Hu et al.
Many cancer cells utilize aerobic glycolysis (also known as the 'Warburg effect'), instead of mitochondrial oxidative phosphorylation, to generate the energy necessary for diverse cellular processes. In tumor cells, mitochondria play more i...