Proteomic tools against the neglected pathology of snake bite envenoming [0.03%]
蛋白质组学工具对抗被蛇咬伤的 neglected pathology
Juan J Calvete
Juan J Calvete
This article covers the application of proteomic tools ('venomics', 'antivenomics' and 'venom phenotyping') to study the composition and natural history of snake venoms, and the cross-reactivity of antivenoms with homologous and heterologou...
Michel Prudent,Jean-Daniel Tissot,Niels Lion
Michel Prudent
Proteomics has changed the way proteins are analyzed in living systems. This approach has been applied to blood products and protein profiling has evolved in parallel with the development of techniques. The identification of proteins belong...
Recent advances in biomarker discovery in solid organ transplant by proteomics [0.03%]
蛋白质组学在实体器官移植生物标志物发现中的最新进展
Tara K Sigdel,Minnie M Sarwal
Tara K Sigdel
The identification and clinical use of more sensitive and specific biomarkers in the field of solid organ transplantation is an urgent need in medicine. Solid organ transplantation has seen improvements in the short-term survival of transpl...
Athina Samara,George T Tsangaris
Athina Samara
Biological systems demonstrate asymmetry, while lateralization has been observed from humans to lower animals structurally, functionally and behaviorally. This may be derived from evolutionary, genetic, developmental, epigenetic and patholo...
William C S Cho
William C S Cho
Comprehensive and in-depth discovery of the disease proteome is an important issue in recent proteomics developments. Previous studies have shown a number of biomarkers discovered in various diseases, including lung cancer. Some of them are...
Timothy D Veenstra
Timothy D Veenstra
Kevin M Coombs
Kevin M Coombs
Measurement of biologically important effector protein molecules has been a long-standing essential component of biological research. Advances in biotechnology, in the form of high-resolution mass spectrometers, and in bioinformatics, now a...
Algorithms for the de novo sequencing of peptides from tandem mass spectra [0.03%]
从串联质谱图上对肽段的从头测序算法研究
Jens Allmer
Jens Allmer
Proteomics is the study of proteins, their time- and location-dependent expression profiles, as well as their modifications and interactions. Mass spectrometry is useful to investigate many of the questions asked in proteomics. Database sea...
Laura-Mae P Britton,Michelle Gonzales-Cope,Barry M Zee et al.
Laura-Mae P Britton et al.
Histone post-translational modifications (PTMs) comprise one of the most intricate nuclear signaling networks that govern gene expression in a long-term and dynamic fashion. These PTMs are considered to be 'epigenetic' or heritable from one...