Eleven shades of PASEF [0.03%]
PASEF的十一级色彩
Marta L Mendes,Klara F Borrmann,Gunnar Dittmar
Marta L Mendes
Introduction: The introduction of trapped ion mobility spectrometry (TIMS) in combination with fast high-resolution time-of-flight (TOF) mass spectrometry to the proteomics field led to a jump in protein identifications a...
Understanding metabolic resistance strategy of clinically isolated antibiotic-resistant bacteria by proteomic approach [0.03%]
采用蛋白质组学方法分析临床分离耐药细菌的代谢耐药机制
Bo Peng,Hui Li,Xuanxian Peng
Bo Peng
Introduction: Understanding the metabolic regulatory mechanisms leading to antibacterial resistance is important to develop effective control measures. Ar...
Validating proteomic biomarkers in saliva: distinguishing between health and periodontal diseases [0.03%]
口腔唾液蛋白质组生物标志物的验证：健康与牙周病的区别
Büşra Yılmaz,Gülnur Emingil
Büşra Yılmaz
Introduction: Periodontitis is a chronic inflammatory disease characterized by progressive soft tissue and alveolar bone loss due to interactions between microbial dental plaque and the host response. Despite extensive re...
Sara Khorami-Sarvestani,Samir M Hanash,Johannes F Fahrmann et al.
Sara Khorami-Sarvestani et al.
Introduction: Glycosylation, the process of glycan synthesis and attachment to target molecules, is a crucial and common post-translational modification (PTM) in mammalian cells. It affects the protein's hydrophilicity, c...
Formation of the Canadian Artificial Intelligence and Mass Spectrometry for systems biology (CAN-AIMS) consortium [0.03%]
加拿大人工智能和生物质谱系统生物学联盟（CAN-AIMS）的建立
Jennifer Geddes-McAlister,Arnaud Droit
Jennifer Geddes-McAlister
Nandha Kumar Balasubramaniam,Scott Penberthy,David Fenyo et al.
Nandha Kumar Balasubramaniam et al.
Introduction: Biomarker discovery is increasingly moving from single omics to multiomics, as well as from multi-cell omics to single-cell omics. These transitions have increasingly adopted digital transformation technolog...
Cellular thermal shift assay: an approach to identify and assess protein target engagement [0.03%]
细胞热位移测定法：一种鉴定和评估蛋白质靶向结合的方法
Liying Zhang,Yuchuan Wang,Chang Zheng et al.
Liying Zhang et al.
Introduction: A comprehensive and global knowledge of protein target engagement is of vital importance for mechanistic studies and in drug development. Since its initial introduction, the cellular thermal shift assay (CET...
Salivary metabolomics in early detection of oral squamous cell carcinoma - a meta-analysis [0.03%]
唾液代谢组学在口腔鳞癌早期检测中的应用-一项荟萃分析
Karthika Panneerselvam,K Rajkumar,Sathish Kumar et al.
Karthika Panneerselvam et al.
Introduction: Oral squamous cell carcinoma (OSCC) represents the most prevalent form of oral cancer. Potentially malignant disorders of oral mucosa exhibit an elevated propensity for malignant progression. A substantial p...
Enhui Wu,Guanyang Xu,Dong Xie et al.
Enhui Wu et al.
Introduction: Metaproteomics offers insights into the function of complex microbial communities, while it is also capable of revealing microbe-microbe and host-microbe interactions. Data-independent acquisition (DIA) mass...
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection [0.03%]
尿蛋白组学在肾脏移植功能监测和排斥反应检测中的作用促进肾脏移植效果
Merita Rroji,Andreja Figurek,Goce Spasovski
Merita Rroji
Introduction: Kidney transplantation significantly improves the lives of those with end-stage kidney disease, offering best alternative to dialysis. However, transplant success is threatened by the acute and chronic rejec...