Zachery R Gregorich
Zachery R Gregorich
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics [0.03%]
反向疫苗学之路：蛋白质组学和生物信息学的最新进展与局限性
Isidro Sobrino,Margarita Villar,José de la Fuente
Isidro Sobrino
Patient-responsive protein biomarkers for cartilage degeneration and repair identified in the infrapatellar fat pad [0.03%]
膝髌脂肪垫中鉴定出的软骨退变和修复相关的患者响应蛋白标志物
Kaj S Emanuel,Luojiao Huang,Mirella J J Haartmans et al.
Kaj S Emanuel et al.
Objectives: Cartilage defects (CDs) are regarded as early manifestation of osteoarthritis (OA). The infrapatellar fat pad (IPFP) is an important mediator in maintaining joint homeostasis, disease progression and tissue re...
Urine proteomics in cardiovascular disease: advances in biomarker discovery and clinical applications [0.03%]
心血管疾病中的尿液蛋白质组学：生物标志物发现和临床应用的进展
Xiaohong Song,Zhaoran Chen,Yuehong Zheng et al.
Xiaohong Song et al.
Introduction: Cardiovascular diseases (CVDs) are the leading causes of mortality and morbidity worldwide, making early diagnosis and effective treatment essential. As a promising and noninvasive research method, urine pro...
Identifying therapeutic strategies for triple-negative breast cancer via phosphoproteomics [0.03%]
通过磷酸蛋白质组学鉴定三阴性乳腺癌的治疗策略
Yuhan Sheng,Gordon Mills,Xuejiao Zhao
Yuhan Sheng
Introduction: Given the poor prognosis of patients with TNBC, it is urgent to identify new biomarkers and therapeutic targets to enable personalized treatment strategies and improve patient survival. Comprehensive insight...
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets [0.03%]
急性髓系白血病的蛋白质基因组分析以确定治疗靶点
Heather C Murray,Jonathan Sillar,Maddison Chambers et al.
Heather C Murray et al.
Introduction: Acute myeloid leukemia (AML) is an aggressive and poor-prognosis blood cancer. Despite a low mutation burden compared to other cancers, AML is heterogenous and identifying robust therapeutic targets has been...
Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy [0.03%]
口腔鳞状细胞癌组织的蛋白质谱分析发现与免疫相关的蛋白发生改变：对个性化治疗的意义
Akhina Palollathil,Sreeranjini Babu,Chandran S Abhinand et al.
Akhina Palollathil et al.
Objectives: Oral squamous cell carcinoma poses a substantial global health challenge marked by rising mortality rate. Recently, immunotherapy has shown promising results in cancer management by enhancing immune response. ...
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease [0.03%]
蛋白质组学视角下的细胞外基质研究:focus于蛋白变体及其对健康和疾病的影响
Amanpreet Kaur Bains,Alexandra Naba
Amanpreet Kaur Bains
Introduction: The extracellular matrix (ECM) is a highly organized and dynamic network of proteins and glycosaminoglycans that provides critical structural, mechanical, and biochemical support to cells. The functions of t...
Protein biomarkers for subtyping breast cancer and implications for future research: a 2024 update [0.03%]
2024年乳腺癌亚型蛋白质生物标志物及对未来研究的影响的更新报告
Claudius Mueller,Justin B Davis,Virginia Espina
Claudius Mueller
Introduction: Breast cancer subtyping is used clinically for diagnosis, prognosis, and treatment decisions. Subtypes are categorized by cell of origin, histomorphology, gene expression signatures, hormone receptor status,...
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers [0.03%]
甘肽富集技术的优化以识别临床生物标志物
Sherifdeen Onigbinde,Cristian D Gutierrez Reyes,Vishal Sandilya et al.
Sherifdeen Onigbinde et al.
Introduction: The identification and characterization of glycopeptides through LC-MS/MS and advanced enrichment techniques are crucial for advancing clinical glycoproteomics, significantly impacting the discovery of disea...