Association between PRNCR1, PAX8AS1, MEG3, and PTENP1 gene polymorphisms and breast cancer risk [0.03%]
PRNCR1、PAX8AS1、MEG3和PTENP1基因多态性与乳腺癌风险的关系研究
Anoosha Asadi,Fatemeh Barati,Alireza Nakhaee et al.
Anoosha Asadi et al.
Aim: In this study, we examined the polymorphisms of PRNCR1 (rs13252298, rs1456315), PAX8-AS1 (rs4848320) MEG3 (rs7158663), PTENP1 (rs7853346) genes in BC patients and compared it with healthy individuals in an Iranian po...
Efficacy of trastuzumab deruxtecan in treating HER2-low breast cancer leptomeningeal metastasis: a case report [0.03%]
德鲁替康治疗HER2低表达型乳腺癌脑膜转移1例报告
Zeni Kharel,Sarah Stanford,Lauryn E Hemminger et al.
Zeni Kharel et al.
accepted at SABCS 2023, poster presented at SABCS 2023We report the efficacy of trastuzumab deruxtecan (T-DXd) in treating human epidermal growth factor receptor 2 (HER2) low, type ID leptomeningeal breast cancer (LMD) (with positive cerebr...
Lung cancer, platinum analog-based frontline treatment and pharmacogenetic limitations [0.03%]
肺癌一线含铂化疗及药物基因限制因素
Maryam Saqib,Zari Salahud Din,Sehrish Zafar et al.
Maryam Saqib et al.
Lung cancer has the highest mortality rate among all the highly prevalent neoplasia globally. The major concern with its frontline treatment-cisplatin, is the rapid progression of chemoresistance and multi-organ-based toxicities including h...
The rs2275738 variant of the adiponectin receptor 1 gene is associated with biopsy-proven nonalcoholic fatty liver disease [0.03%]
载脂蛋白受体1基因的rs2275738突变型与经活检证实的非酒精性脂肪肝病相关
Mitra Rostami,Touraj Mahmoudi,Abbas Ardalani et al.
Mitra Rostami et al.
Aim: Nonalcoholic fatty liver disease (NAFLD) is a significant health issue worldwide. This study investigated the effect of the adiponectin receptor 1 gene (ADIPOR1) polymorphism on susceptibility to NAFLD.Methods: Data from 330 participan...
Introduction of a single-nucleotide variant, rs16851030, into the ADORA1 gene increased cellular susceptibility to hypoxia [0.03%]
在ADORA1基因中引入单核苷酸变异体rs16851030可增加细胞对缺氧的易感性
Poh Kuan Wong,Saiful Effendi Syafruddin,Fook Choe Cheah et al.
Poh Kuan Wong et al.
Aim: Rs16851030, a single-nucleotide variant located in the 3'-untranslated region of the ADORA1 gene, has been proposed as a potential marker of caffeine sensitivity in apnea of prematurity. Besides, it is associated with aspirin-induced a...
miR-559 rs58450758 polymorphism is associated with colorectal cancer risk and prognosis in Chinese Han population [0.03%]
微RNA-559基因多态性与汉族人群结直肠癌发病及预后关系的研究
Hanxing Huang,Lihan Xiao,Min Xiao et al.
Hanxing Huang et al.
Aim: This research examined the correlation between miR-559 rs58450758 and the clinical pathological characteristics and prognosis of CRC.Materials & methods: RT-qPCR was utilized to assess the miR-559 expression levels. Chi-square test was...
Impact of MIR137HG rs7554283 on susceptibility to high-altitude pulmonary edema in the Chinese population [0.03%]
汉族人群MIR137HG基因rs7554283多态性与高原肺水肿易感性的关联研究
Shilin Xu,Xuemei Li,Xuguang Li et al.
Shilin Xu et al.
Aim: MIR137 host gene (MIR137HG) variants were involved in a variety of diseases, but its role in high-altitude pulmonary edema (HAPE) has not been reported. The study aimed to study the association between MIR137HG single-nucleotide polymo...
Precision medicine activities and opportunities for shaping maternal and neonatal health in Qatar [0.03%]
卡塔尔的精准医学活动及妇女和新生儿卫生成形机遇
Nader Al-Dewik,Tala Abuarja,Salma Younes et al.
Nader Al-Dewik et al.
Precision Medicine (PM) is a transformative clinical medicine strategy that aims to revolutionize healthcare by leveraging biological information and biomarkers. In the context of maternal and neonatal health, PM enables personalized care f...
Association between IL-6, miRNA-146a, MALAT1 genetic polymorphisms and risk of rheumatoid arthritis [0.03%]
白细胞介素-6、微小核糖核酸-146a及MALAT1基因多态性与类风湿关节炎发病风险关联研究
Yasser Bm Ali,Noura Ma Hasan,Eman A El-Maadawy et al.
Yasser Bm Ali et al.
Aim: This study aimed to investigate the associations between single nucleotide polymorphisms (SNPs) of IL-6 (-174G/C), microRNA146a (rs2910164C/G) and MALAT1 (rs619586A/G) and susceptibility to rheumatoid arthritis (RA) in Egyptians.Method...
Development of a computer-based tool to obtain a family health history in Vietnam [0.03%]
在越南开发一种基于计算机的工具以获取家族健康史
Linh Ba Tieu,Vinh Nhu Nguyen,Phu Gia Tran et al.
Linh Ba Tieu et al.
Background: Family health history (FHH) is central to human genomic profiling construction; however, there is no protocol for documenting FHH in a pedigree format in Vietnam.Aim: A "Gia Su Suc Khoe" (GSSK) tool was developed to create a use...