Introduction of a single-nucleotide variant, rs16851030, into the ADORA1 gene increased cellular susceptibility to hypoxia [0.03%]
在ADORA1基因中引入单核苷酸变异体rs16851030可增加细胞对缺氧的易感性
Poh Kuan Wong,Saiful Effendi Syafruddin,Fook Choe Cheah et al.
Poh Kuan Wong et al.
Aim: Rs16851030, a single-nucleotide variant located in the 3'-untranslated region of the ADORA1 gene, has been proposed as a potential marker of caffeine sensitivity in apnea of prematurity. Besides, it is associated with aspirin-induced a...
miR-559 rs58450758 polymorphism is associated with colorectal cancer risk and prognosis in Chinese Han population [0.03%]
微RNA-559基因多态性与汉族人群结直肠癌发病及预后关系的研究
Hanxing Huang,Lihan Xiao,Min Xiao et al.
Hanxing Huang et al.
Aim: This research examined the correlation between miR-559 rs58450758 and the clinical pathological characteristics and prognosis of CRC.Materials & methods: RT-qPCR was utilized to assess the miR-559 expression levels. Chi-square test was...
Impact of MIR137HG rs7554283 on susceptibility to high-altitude pulmonary edema in the Chinese population [0.03%]
汉族人群MIR137HG基因rs7554283多态性与高原肺水肿易感性的关联研究
Shilin Xu,Xuemei Li,Xuguang Li et al.
Shilin Xu et al.
Aim: MIR137 host gene (MIR137HG) variants were involved in a variety of diseases, but its role in high-altitude pulmonary edema (HAPE) has not been reported. The study aimed to study the association between MIR137HG single-nucleotide polymo...
Precision medicine activities and opportunities for shaping maternal and neonatal health in Qatar [0.03%]
卡塔尔的精准医学活动及妇女和新生儿卫生成形机遇
Nader Al-Dewik,Tala Abuarja,Salma Younes et al.
Nader Al-Dewik et al.
Precision Medicine (PM) is a transformative clinical medicine strategy that aims to revolutionize healthcare by leveraging biological information and biomarkers. In the context of maternal and neonatal health, PM enables personalized care f...
Association between IL-6, miRNA-146a, MALAT1 genetic polymorphisms and risk of rheumatoid arthritis [0.03%]
白细胞介素-6、微小核糖核酸-146a及MALAT1基因多态性与类风湿关节炎发病风险关联研究
Yasser Bm Ali,Noura Ma Hasan,Eman A El-Maadawy et al.
Yasser Bm Ali et al.
Aim: This study aimed to investigate the associations between single nucleotide polymorphisms (SNPs) of IL-6 (-174G/C), microRNA146a (rs2910164C/G) and MALAT1 (rs619586A/G) and susceptibility to rheumatoid arthritis (RA) in Egyptians.Method...
Development of a computer-based tool to obtain a family health history in Vietnam [0.03%]
在越南开发一种基于计算机的工具以获取家族健康史
Linh Ba Tieu,Vinh Nhu Nguyen,Phu Gia Tran et al.
Linh Ba Tieu et al.
Background: Family health history (FHH) is central to human genomic profiling construction; however, there is no protocol for documenting FHH in a pedigree format in Vietnam.Aim: A "Gia Su Suc Khoe" (GSSK) tool was developed to create a use...
The effect of RNLS gene polymorphisms on preeclampsia susceptibility: a meta-analysis study [0.03%]
关于RNLS基因多态性与子痫前期易感性的关联：一项荟萃分析研究
Saeedeh Salimi,Abbas Mohammadpour-Gharehbagh,Mohaddeseh Hedayat et al.
Saeedeh Salimi et al.
Aim: The authors designed a meta-analysis to find a comprehensive result of the impact of RNLS polymorphisms on preeclampsia (PE) susceptibility. Methods: The online databases PubMed, Scopus, and Google Scholar were employed for the purpose...
Improving resource allocation in the precision medicine Era: a simulation-based approach using R [0.03%]
基于R的模拟方法在精准医学时代改善资源分配
Mohamed Kamal,Mohamed Nagy,Omneya Hassanain
Mohamed Kamal
The application of personalized medicine in developing countries is a major challenge, especially for those with poor economic status. A critical factor in improving the application of personalized medicine is the efficient allocation of re...
European survey: citizens' attitudes on personalized medicine, genetic testing and health data sharing - design and delivery [0.03%]
欧洲调查：关于个体化医学、基因检测和健康数据共享的公民态度——设计与实施
Francesco Andrea Causio,Flavia Beccia,Loes Lindiwe Kreeftenberg et al.
Francesco Andrea Causio et al.
In the transformative landscape of healthcare, personalized medicine emerges as a pivotal shift, harnessing genetic, environmental and lifestyle data to tailor medical treatments for enhanced outcomes and cost efficiency. Central to its suc...
Optimizing vancomycin therapeutic drug monitoring compliance in pediatric oncology: towards personalized medication management [0.03%]
儿科肿瘤学万古霉素治疗药物监测的优化：迈向个性化药物管理
Rewan Gamal Mohamed,Rania Saber,Mohamed Ali Hussein et al.
Rewan Gamal Mohamed et al.
Aim: Vancomycin, a crucial treatment for Gram-positive bacteria, necessitates therapeutic drug monitoring (TDM) to prevent treatment failures. We investigated the healthcare professional's compliance toward TDM of vancomycin recommendations...