Corrigendum [0.03%]
勘误表
Published Erratum
Pharmacogenomics. 2018 May;19(7):687. DOI:10.2217/pgs-2017-0014c1 2018
A genetic polymorphism in the CYP1B1 gene in patients with squamous cell carcinoma of the esophagus: an Iranian Mashhad cohort study recruited over 10 years [0.03%]
一项针对伊朗马什哈德10年队列食管鳞状细胞癌患者CYP1B1基因多态性的研究
Azam Rastgar Moghadam,Mehrane Mehramiz,Malihe Entezari et al.
Azam Rastgar Moghadam et al.
Aim: Esophageal cancer is the eighth most common cancer globally and the seventh most common cause of cancer-related deaths in men. Recent studies have shown that CYP450, family 1, subfamily B, polypeptide 1, which plays ...
CYP3A pharmacogenetic association with tacrolimus pharmacokinetics differs based on route of drug administration [0.03%]
基于给药途径的不同，细胞色素P450 3A基因多态性与他克莫司药物代谢动力学相关性不同
Amy L Pasternak,Lu Zhang,Daniel L Hertz
Amy L Pasternak
Tacrolimus is prescribed to the majority of transplant recipients to prevent graft rejection, and although patients are maintained on oral administration, nonoral routes of administration are frequently used in the initial post-transplant p...
Association between HLA-B*15:02 and oxcarbazepine-induced cutaneous adverse reaction: a meta-analysis [0.03%]
HLA-B*15:02与奥卡西平致皮疹的meta分析
Yiwei Liu,Yuncui Yu,Xiaolu Nie et al.
Yiwei Liu et al.
Aim: HLA-B*15:02 has been demonstrated as a key risk factor for carbamazepine-induced severe cutaneous adverse reaction (sCAR), especially in Asian population. Oxcarbazepine (OXC) is a drug that has a similar structure of...
Meta-Analysis
Pharmacogenomics. 2018 Apr;19(6):547-552. DOI:10.2217/pgs-2017-0189 2018
The 9p21 locus as a potential therapeutic target and prognostic marker in colorectal cancer [0.03%]
9p21位点在结直肠癌中的治疗靶点和预后标志物作用研究
Afsane Bahrami,Seyed Mahdi Hassanian,Majid Khazaei et al.
Afsane Bahrami et al.
Colorectal cancer (CRC) is a major cause of cancer-related-death worldwide. Despite extensive efforts to identify valid biomarkers for the risk stratification of CRC patients, there are few of proven clinical utility. It is recognized that ...
Clinical pharmacogenetics: how do we ensure a favorable future for patients? [0.03%]
临床药物基因组学：我们如何为患者创造美好未来？
Tim Wiltshire,Olivia M Dong
Tim Wiltshire
Currently, there is sufficient evidence for the use of pharmacogenetic information to optimize medication prescribing, but why has this information not been integrated into the drug prescribing process to improve patient care? A discussion ...
Transient receptor potential polymorphism and haplotype associate with crisis pain in sickle cell disease [0.03%]
瞬时受体多肽多态性与镰状细胞病危象痛的关系研究
Ellie H Jhun,Xiaoyu Hu,Nilanjana Sadhu et al.
Ellie H Jhun et al.
Aim: Episodes of acute pain crisis contribute to considerable morbidity and mortality in sickle cell disease (SCD). Incomprehensive understanding of the underlying pain heterogeneity results in inadequate pain management....
Associations between gene polymorphisms and treatment outcomes of methotrexate in patients with juvenile idiopathic arthritis [0.03%]
儿童期特发性关节炎甲氨蝶呤治疗效果与基因多态性的关联性研究
Yuehong Chen,Kun Zou,Jianhong Sun et al.
Yuehong Chen et al.
Aim: Performance of a meta-analysis with respect to the genetic predictors of methotrexate (MTX) treatment outcomes, efficacy and toxicity, in patients with juvenile idiopathic arthritis (JIA). ...
Meta-Analysis
Pharmacogenomics. 2018 Apr;19(6):529-538. DOI:10.2217/pgs-2017-0208 2018
Anna-Maria Ordelheide,Martin Hrabě de Angelis,Hans-Ulrich Häring et al.
Anna-Maria Ordelheide et al.
Type 2 diabetes prevalence is still on the rise worldwide. Antidiabetic drugs are widely prescribed to patients with Type 2 diabetes. Most patients start with metformin which is mostly well tolerated. However, a high percentage of patients ...
Effect of hydrochlorothiazide on serum uric acid concentration: a genome-wide association study [0.03%]
氢氯噻嗪对血尿酸浓度影响的全基因组关联研究
Eero M Ala-Mutka,Jenni M Rimpelä,Frej Fyhrquist et al.
Eero M Ala-Mutka et al.
Aim: To recognize genetic associations of hydrochlorothiazide-induced change in serum uric acid (SUA) concentration. Patients & methods: ...