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期刊名:Pharmacogenomics

缩写:PHARMACOGENOMICS

ISSN:1462-2416

e-ISSN:1744-8042

IF/分区:1.9/Q3

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共收录本刊相关文章索引2769
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Yu Wu,Lihuan Lu,Fei Wang et al. Yu Wu et al.
Aims: To screen and validate rare variants in the protoporphyrin IX (PPIX)-metabolizing pathway associated with anti-tuberculosis drug-induced hepatitis (AT-DIH). ...
Tinashe Adrian Mazhindu,Ntokozo Ndlovu,Margaret Z Borok et al. Tinashe Adrian Mazhindu et al.
Introduction: Supportive care in oncology aims to prevent and manage cancer-related side effects. This study reviews supportive medications for gastrointestinal cancer patients, analyzes usage patterns, biomarker frequenc...
Tanuma Mistry,Partha Nath,Neyaz Alam et al. Tanuma Mistry et al.
Aims: Sequential Anthracycline-Taxane chemotherapy is standard treatment for BC. This study examines the combined impact of low BMI and CYP polymorphisms on treatment response. ...
Litaty C Mbatchi,Fanny Leenhardt,Bob-Valéry Occean et al. Litaty C Mbatchi et al.
Purpose: Sunitinib is a multikinase inhibitor used to treat metastatic renal cell carcinoma (mRCC), with an inter-individual variability of pharmacokinetics and toxicity. Our goal was to assess associations between the ph...
Anantha Lakshmi Jakka,Ripsy Merrin Chacko,Mallikarjun Vasam et al. Anantha Lakshmi Jakka et al.
At the crossroads of genomics and pharmacology, pharmacogenomics is revolutionizing healthcare by tailoring drug therapies to individual genetic profiles thereby reducing the risk of adverse drug reactions and propelling the field of precis...
Erin L Fletcher,Alison O Cudmore,Barbara C Vanderhyden Erin L Fletcher
Ovarian cancers (OCs) are often defined as poorly immunogenic tumors that have low response rates to current immunotherapies and frequently develop resistance to chemotherapies. Oncolytic viruses (OVs) are an emerging therapeutic approach t...
Daiane Keller Cecconello,Klerize Anecely de Souza Silva,Evelin Cristine Mendonça de Senna et al. Daiane Keller Cecconello et al.
Aims: Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Although PEG-asparaginase (PEG-ASNase) is a key drug in treatment, hypersensitivity reactions, pancreatitis, and silent inactivation remain maj...
Jiaodi Zhang,Qi Jin,Tao Chen et al. Jiaodi Zhang et al.
Aim: This study aimed to assess the impact of GSTP1, GSTM1, and GSTT1 polymorphisms on the response to oxaliplatin-based chemotherapy and survival outcomes in gastric cancer patients from Northwest China. ...
J F Vieira,I H Tassoni,M L Chaves et al. J F Vieira et al.
The CYP2C19 gene encodes one of the main enzymes responsible for clopidogrel bioactivation, a widely prescribed antiplatelet prodrug. Due to its high polymorphism, clopidogrel response varies considerably, especially in carriers of nonfunct...