Karin B Mirzaev,Denis S Fedorinov,Dmitry V Ivashchenko et al.
Karin B Mirzaev et al.
This systematic review reflects the results of pharmacogenetic studies in the Russian Federation aimed at studying the genes involved in the drug biotransformation system. The works of Russian researchers found by us are mostly devoted to m...
Sanjida Ahmed,Zia Choudhry,Junaid A Bhatti
Sanjida Ahmed
We conducted a scoping review on genetic polymorphisms associated with opioid intake-related adverse patient outcomes including behavioral, physiological and clinical outcomes. We searched for studies on Medline®, EMBASE®, CINAHL®, Psych...
The ANKS1B gene and its associated phenotypes: focus on CNS drug response [0.03%]
ANKS1B基因及其相关表型：重点关注中枢神经系统药物反应
Rabha M Younis,Rachel M Taylor,Patrick M Beardsley et al.
Rabha M Younis et al.
The ANKS1B gene was a top finding in genome-wide association studies (GWAS) of antipsychotic drug response. Subsequent GWAS findings for ANKS1B include cognitive ability, educational attainment, body mass index, response to corticosteroids ...
Pharmacogenomics education in medical and pharmacy schools: conclusions of a global survey [0.03%]
全球药学教育调查结论
Nataša Karas Kuželički,Irena Prodan Žitnik,David Gurwitz et al.
Nataša Karas Kuželički et al.
Aim: The need for pharmacogenomic education is becoming more and more urgent. Our aim was to evaluate the progress in pharmacogenomics education since then, and to put forward further recommendations. Methods: A survey was sent to 248 schoo...
Genetics of high-dose methotrexate-induced oral mucositis: current perspectives [0.03%]
高剂量甲氨蝶呤致口腔粘膜炎的遗传学：当前观点
Sandra G Heil
Sandra G Heil
Susanne B Haga,Jivan Moaddeb
Susanne B Haga
Aim: The appropriate use and integration of pharmacogenetic (PGx) testing will pivot on provider preparation and training. Pharmacists have been recognized as one of the key providers in the delivery of PGx testing and as such, professional...
The pharmacogenetics of OATP1B1 variants and their impact on the pharmacokinetics and efficacy of elbasvir/grazoprevir [0.03%]
OATP1B1基因多态性对艾伯维公司Elbasvir/grazoprevir药代动力学及疗效的影响研究
Zifang Guo,Luzelena Caro,Michael N Robertson et al.
Zifang Guo et al.
Aim: To evaluate the effect of SLCO1B1 genetic variants on grazoprevir pharmacokinetics and efficacy. Methods: A retrospective analysis of 1578 hepatitis C virus-infected participants from ten Phase II/III clinical trials. Results: Relative...
Patient characteristics, experiences and perceived value of pharmacogenetic testing from a single testing laboratory [0.03%]
一家单一样本实验室的药物基因检测患者的特征、体验及感知价值
Susanne B Haga,Yiling Liu
Susanne B Haga
Aims: Patients' use of and experience with pharmacogenetic (PGx) testing may be impacted by several factors including patient and provider knowledge, health status, and perceived understanding of results. Materials & Methods: We conducted a...
Pharmacogenetic testing in primary care practice: opinions of physicians, pharmacists and patients [0.03%]
初级保健实践中的药物基因检测：医生、药师和患者的看法
Marie-Pier Frigon,Marie-Ève Blackburn,Camélia Dubois-Bouchard et al.
Marie-Pier Frigon et al.
Aim: Although health authorities have set pharmacogenetic (PGx) markers on labels of hundreds of drugs, the use of PGx in clinical care remains infrequent. The adoption of PGx will depend on the opinions of physicians, pharmacists and patie...
High levels of several antipsychotics and antidepressants due to a pharmacogenetic cause: a case report [0.03%]
由于药理遗传学原因多种抗精神病药物和抗抑郁药物的高浓度：病例报告
Paola Mian,Metten Somers,Maarten Ten Berg et al.
Paola Mian et al.
Pharmacogenetic analysis to explain or predict the response of a specific patient to drug therapy is increasingly used in clinical practice. This holds especially true for CYP genotyping in psychiatry. We present a patient with genetic poly...
Case Reports
Pharmacogenomics. 2019 Jun;20(8):567-570. DOI:10.2217/pgs-2019-0037 2019