Safety and tolerability of fremanezumab for treating migraine: where are we now? [0.03%]
法瑞莫单抗治疗偏头痛的安全性和耐受性如何？目前进展到哪一步了？
Carolin Luisa Hoehne,Bianca Raffaelli
Carolin Luisa Hoehne
CYP450 activity, drug interactions and genetic polymorphisms: clinical relevance for the new selective cardiac myosin inhibitors [0.03%]
细胞色素P450活性、药物相互作用和基因多态性：新型选择性心脏肌球蛋白抑制剂的临床意义
Milind Y Desai,Veronique Michaud,David Thacker et al.
Milind Y Desai et al.
Introduction: Several sarcomeric gene abnormalities associated with left ventricular thickening, hypercontractility, and high left ventricular ejection fraction define hypertrophic cardiomyopathy (HCM). Standard treatment...
Comparison of ciprofol and propofol on dreaming and emotional response during painless gastroscopy: a single-center randomized controlled trial [0.03%]
右美托咪定和丙泊酚无痛胃镜诊疗的梦境及情绪反应特点单中心随机对照研究
Luran Xiong,Kunjie Li,Xinyi Feng et al.
Luran Xiong et al.
Background and aims: Ciprofol (HSK3486), a novel intravenous anesthetic with a chemical structure similar to propofol, is not inferior to propofol in terms of its effectiveness. We compared the effects of ciprofol and pro...
Safety and efficacy of anticoagulant administration in people with atrial fibrillation and advanced chronic kidney disease [0.03%]
房颤和慢性肾病进展期患者的抗凝治疗的安全性和有效性
Krzysztof Irlik,Hanna Kwiendacz,Wiktoria Ignacy et al.
Krzysztof Irlik et al.
Introduction: Advanced chronic kidney disease (CKD), defined as an estimated glomerular filtration rate < 30 ml/min/1.73 m2, significantly amplifies the challenges of managing atrial fibrillation (AF), highly prevalent in...
Amanda DeLuca,Ashley Schultz,Hannah Ofori et al.
Amanda DeLuca et al.
Introduction: Insulin remains the mainstay of diabetes management. Once weekly insulins (OWI) being investigated as viable options for both type 1 and type 2 diabetes. Less frequent dosing and better pharmacokinetic profi...
Impact of sodium glucose cotransporter 2 inhibitors on bladder cancer and breast cancer: a pharmacovigilance analysis and mendelian randomization study [0.03%]
钠-葡萄糖共转运蛋白2抑制剂对膀胱癌和乳腺癌的影响：药物警戒分析和孟德尔随机化研究
Bo Xu,Tianqiao Zhang,Yechuan He et al.
Bo Xu et al.
Background: There is conflicting real-world evidence regarding the risk of breast and bladder cancer associated with sodium glucose cotransporter 2 (SGLT2) inhibitors. We conducted a pharmacovigilance study on SGLT2 inhib...
Comparative analysis of adverse events between sacubitril/valsartan and valsartan using the FAERS database: a disproportionality analysis [0.03%]
基于FAERS数据库的沙库必曲/缬沙坦与缬沙坦不良事件比较分析：不均衡分析方法
Da Li,Yunfeng Li,Lei Yao et al.
Da Li et al.
Background: This study conducts a comprehensive comparative analysis of adverse event (AE) signals between sacubitril/valsartan and valsartan, two pivotal cardiovascular drugs for heart failure and hypertension, utilizing...
Diana Varghese,Kashif M Munir,Stephen N Davis
Diana Varghese
Ricardo Ruiz-Villaverde,Marta Cebolla-Verdugo,Jose Molina-Espinosa
Ricardo Ruiz-Villaverde
Andrea Spini,Chiara Bellitto,Gianluca Trifirò
Andrea Spini