Claudin-6 as a potential target in the treatment of ovarian cancer: a review of emerging drugs [0.03%]
Claudin-6在卵巢癌治疗中的潜在作用及新兴药物研发进展综述
Sarah Ottum,Namrata Sethi,Cem Demirkiran et al.
Sarah Ottum et al.
Introduction: Claudins are integral components of tight junctions with emerging roles in cancer biology. Dysregulated claudin expression during malignant transformation exposes these proteins on the tumor cell surface, cr...
Drug discovery progress in targeting the renin-angiotensin-aldosterone system for heart failure [0.03%]
针对心力衰竭靶向肾素血管紧张素醛固酮系统的药物研发进展
Diksha Choudhary,Nisha Bansal,Bhupinder Kumar
Diksha Choudhary
Emerging biological drugs for the treatment of patients with metastatic HER2+ gastroesophageal adenocarcinomas [0.03%]
治疗转移性HER2阳性胃食管腺癌患者的新兴生物药物
Jane E Rogers,Ashley Horak,Alicia Kroll et al.
Jane E Rogers et al.
Introduction: Advanced gastroesophageal adenocarcinomas (GEAs) continue to represent an area in need of new drug development. Targeting human epidermal growth factor receptor-2 (HER2) in GEAs has been standard since 2010 ...
σ1 receptor agonists: the new trend or an emerging therapeutic option? [0.03%]
sigma1受体激动剂：新趋势还是潜在的治疗选择？
Tangui Maurice
Tangui Maurice
Obefazimod (ABX464) for Moderate-to-Severe Crohn's disease: clinical development of a novel oral therapeutic approach [0.03%]
新型口服疗法奥贝法齐姆（ABX464）治疗中重度克罗恩病的临床研发
Sailish Honap,Axel Dignass,Vipul Jairath et al.
Sailish Honap et al.
Evaluating emerging amyloid-β centric drugs for the treatment of Alzheimer's disease [0.03%]
评估新兴的以淀粉样蛋白-β为中心的药物治疗阿尔茨海默病的效果
Madia Lozupone,Vittorio Dibello,Rodolfo Sardone et al.
Madia Lozupone et al.
Introduction: The amyloid cascade hypothesis provided a compelling rationale for Alzheimer's disease (AD) drug development, but many amyloid-β (Aβ)-targeted agents failed to show benefit. The present review article eval...
Emerging treatment options for chronic obstructive pulmonary disease: a look into 2026 and beyond [0.03%]
慢性阻塞性肺疾病的新兴治疗选择：展望2026及以后
Carolyn J Wang,Clarus Leung,Don D Sin
Carolyn J Wang
Introduction: As a leading cause of worldwide mortality, chronic obstructive pulmonary disease (COPD) is progressive and irreversible, leading to significant challenges with disease management and treatment. This is furth...
Beyond triptans in menstrual migraine: the emerging role of CGRP-targeted therapies [0.03%]
月經性偏頭痛的曲普坦之外：CGRP治療的新角色
Lanfranco Pellesi,Damiana Scuteri,Andrea Burgalassi et al.
Lanfranco Pellesi et al.
Introduction: Menstrual migraine is a common and disabling subtype of migraine, linked to hormonal fluctuations and characterized by attacks that are often more severe, longer lasting and less responsive to treatment than...
Acute management of MOGAD: therapeutic choices and clinical outcomes [0.03%]
视神经脊髓炎谱系疾病急性期的治疗选择及临床结局分析
Edgar Carnero Contentti,Eoin P Flanagan,Ethel Ciampi
Edgar Carnero Contentti
Antonella Riva,Sara Di Gioacchino,Greta Volpedo et al.
Antonella Riva et al.
Introduction: Dravet syndrome (DS), a catastrophic developmental and epileptic encephalopathy primarily caused by SCN1A haploinsufficiency, remains largely refractory to current antiseizure medications. In recent years, g...