Somnath Das,Manish Kumar,Subhrojyoti Mukherjee et al.
Somnath Das et al.
Introduction: Bi-gels are a novel drug delivery system that enhances the regulated and targeted release of anticancer therapies by combining hydrogels and organogels. These dual-phase systems, including a hydrophilic poly...
Chiara Bastiancich,Chiara Molinar,A Tchoghandjian et al.
Chiara Bastiancich et al.
Introduction: Dextrins are biodegradable, highly soluble, natural derivatives of starch, which occur in two main forms, either as linear polymers or as cyclic oligosaccharides, commonly known as cyclodextrins. The two str...
Janaki Iyer,Arvind Hariharan,Riho Kanai et al.
Janaki Iyer et al.
Introduction: Systemic equilibrium, oral health, and digestion depend on the health of the salivary glands (SGs). SG disorders, such as Sjögren's syndrome, oral and maxillofacial cancer, and radiation-induced damage, are...
Shivam Pathak,Rupam Bera,Anjana Sharma et al.
Shivam Pathak et al.
Introduction: Colorectal cancer remains one of the most prevalent and lethal malignancies worldwide, with treatment often hampered by poor drug bioavailability, systemic toxicity, and resistance to conventional therapies....
Advanced nano-delivery systems in H. pylori eradication: targeting, efficacy, and clinical translation [0.03%]
幽门螺杆菌根除的先进纳米输送系统:目标、功效和临床转化
Tehsin Ullah Khan,Mohamed Sharaf,Sohaib Khan et al.
Tehsin Ullah Khan et al.
Introduction: Helicobacter pylori infections demand innovative therapeutic strategies due to rising antibiotic resistance. This review consolidates recent advances in nanoparticle (NP)-based drug delivery systems engineer...
Future outcomes and current limitations of injectable implants for vocal Fold scarring [0.03%]
注射式植入物治疗声带瘢痕的未来展望及目前局限性
Nour Awad,Denel Ryan D Cruz,Luigi Melaragno et al.
Nour Awad et al.
Introduction: Vocal fold scarring poses a significant challenge. It is characterized by prolonged and often irreversible impairment of vocal function due to loss of pliability and disruption of the lamina propria's native...
Attenuating amygdalin (vitamin B17) toxicity for potential therapeutic uses: insights into controlled release technology-based formulations as a strategy for improving clinical safety [0.03%]
基于控制释放技术的制剂改善临床安全性的策略——用于潜在治疗用途的苦杏仁素(维生素B17)解毒研究初探
Zubair Khalid Baig Moghal,Rajesh Sreedharan Nair,Saghir Akhtar et al.
Zubair Khalid Baig Moghal et al.
Introduction: Amygdalin, is arguably, one of the most controversial molecules found in nature, with several therapeutic properties, including anticancer, but there are concerns over its toxicity on healthy tissue alike, w...
Can nanoparticle-based intranasal delivery systems revolutionize treatment of central nervous system diseases? [0.03%]
纳米颗粒为基础的鼻内输送系统能够革新中枢神经系统疾病的治疗吗?
Giuseppe Nunziata,Fabio Pizzetti,Pietro Veglianese et al.
Giuseppe Nunziata et al.
Differential targeting of olfactory epithelium and respiratory epithelium in nose-to-brain drug delivery [0.03%]
鼻递脑药物传输中嗅上皮和呼吸上皮的选择性定位作用差异研究
Anisha A DSouza,Valentina DiFrancesco,Alicia Yang et al.
Anisha A DSouza et al.
Introduction: Nose-to-brain drug delivery provides a promising noninvasive route to bypass the blood-brain barrier through direct nasal cavity-brain connections. Therapeutic agents reach the central nervous system via sys...
Improving nasal spray deposition: advances and strategies to overcome anatomical and physiological barriers [0.03%]
改善鼻喷剂沉积:克服解剖和生理屏障的进展与策略
Amr Seifelnasr,Xiuhua Si,Jack Yongfeng Zhang et al.
Amr Seifelnasr et al.
Introduction: Nasal sprays offer a versatile, noninvasive delivery route for topical, systemic, immunological, and nose-to-brain therapies, yet effective targeting is limited by nasal anatomical complexity and physiologic...