Ibrahim M A Hussein,Ilona Krabicová,Gjylije Hoti et al.
Ibrahim M A Hussein et al.
Introduction: Cyclodextrin-based drug delivery systems provide a robust platform for designing targeted nanocarriers that efficiently encapsulate, stabilize, and deliver poorly soluble drugs to specific sites. Their uniqu...
Intra-articular targeted delivery of nanomaterials for the treatment of osteoarthritis: focusing on cell signaling pathway mechanisms [0.03%]
纳米材料的关节腔靶向递送治疗骨关节炎：着眼于细胞信号转导机制
Bo Gu,Jingjing Qi,Xin Li et al.
Bo Gu et al.
Introduction: This review summarizes the application of nanomaterial-mediated intra-articular targeted drug delivery systems in the treatment of osteoarthritis (OA) and their regulatory mechanisms on key cellular signalin...
Targeted delivery of therapeutics to the heart with calcium phosphate nanoparticles [0.03%]
利用钙磷酸盐纳米颗粒靶向投递心脏药物治疗
Camilla Fusacchia,Federica Mancini,Alessio Adamiano et al.
Camilla Fusacchia et al.
Introduction: Cardiovascular diseases (CVDs) remain the leading cause of global mortality, with conventional therapies mainly providing symptomatic relief without targeting underlying molecular and cellular mechanisms. Ad...
Interaction of nanodrug delivery systems via fibroblasts in colorectal cancer [0.03%]
纳米药物传递系统通过结直肠癌成纤维细胞的相互作用
Wenpeng Wang,Mingrui Li,Ying Liu et al.
Wenpeng Wang et al.
Introduction: Colorectal cancer (CRC) is a major cause of cancer mortality, with poor outcomes driven by the tumor microenvironment (TME). Heterogeneous cancer-associated fibroblasts (CAFs) remodel the extracellular matri...
Recent advances in PDEVs as nanocarriers for drug delivery: loading techniques, engineering strategies and future directions [0.03%]
作为药物输送纳米载体的PDEVs最新进展：负载技术、工程策略和未来方向
Bharathipriya Rajasekaran,Kai-Jiun Lo,Min-Hsiung Pan
Bharathipriya Rajasekaran
Introduction: Plant-derived extracellular vesicles (PDEVs) have emerged as natural nanocarriers with promising applications in drug delivery and precision medicine. Secreted by plant cells, PDEVs facilitate intercellular ...
Plant-derived extracellular vesicles: emerging carriers for ingestible nucleotide delivery [0.03%]
植物来源的细胞外囊泡：可摄入式核酸传递的新载体
Zhuo Li,Wei Jin,Minyu Zhu et al.
Zhuo Li et al.
Introduction: Plant-derived extracellular vesicles (PEVs) have shown significant promise as a novel oral delivery system for nucleotide-based drugs. The successful oral delivery of nucleotide drugs using PEVs paves the wa...
Calcium carbonate in drug delivery: functional carrier design, applications, and data-driven perspectives [0.03%]
药物传递中的碳酸钙：功能载体设计、应用和数据驱动观点
Saba Taheri,Dmitry V Volodkin,Andre G Skirtach et al.
Saba Taheri et al.
Introduction: Calcium carbonate particles are a very potent type of inorganic drug delivery carrier, which have attractive pH responsiveness, strong mechanical properties, and a relatively high loading capacity. Adding or...
Design and labeling differences between generic and reference listed drug inhalers: human factors considerations in us FDA-approved devices [0.03%]
美国FDA批准的药物吸入器的人机工程学差异考虑：通用和参照药物列表之间的设计和标签差异
Brian D Nguyen,Monifa Vaughn-Cooke
Brian D Nguyen
Background: While generic inhalers are approved based on therapeutic equivalence to their reference listed drug (RLD) counterparts, design and labeling differences may unintentionally affect product usability and patient ...
Carlo Diaferia
Carlo Diaferia