Interaction of nanodrug delivery systems via fibroblasts in colorectal cancer [0.03%]
纳米药物传递系统通过结直肠癌成纤维细胞的相互作用
Wenpeng Wang,Mingrui Li,Ying Liu et al.
Wenpeng Wang et al.
Introduction: Colorectal cancer (CRC) is a major cause of cancer mortality, with poor outcomes driven by the tumor microenvironment (TME). Heterogeneous cancer-associated fibroblasts (CAFs) remodel the extracellular matri...
Recent advances in PDEVs as nanocarriers for drug delivery: loading techniques, engineering strategies and future directions [0.03%]
作为药物输送纳米载体的PDEVs最新进展：负载技术、工程策略和未来方向
Bharathipriya Rajasekaran,Kai-Jiun Lo,Min-Hsiung Pan
Bharathipriya Rajasekaran
Introduction: Plant-derived extracellular vesicles (PDEVs) have emerged as natural nanocarriers with promising applications in drug delivery and precision medicine. Secreted by plant cells, PDEVs facilitate intercellular ...
Plant-derived extracellular vesicles: emerging carriers for ingestible nucleotide delivery [0.03%]
植物来源的细胞外囊泡：可摄入式核酸传递的新载体
Zhuo Li,Wei Jin,Minyu Zhu et al.
Zhuo Li et al.
Introduction: Plant-derived extracellular vesicles (PEVs) have shown significant promise as a novel oral delivery system for nucleotide-based drugs. The successful oral delivery of nucleotide drugs using PEVs paves the wa...
Calcium carbonate in drug delivery: functional carrier design, applications, and data-driven perspectives [0.03%]
药物传递中的碳酸钙：功能载体设计、应用和数据驱动观点
Saba Taheri,Dmitry V Volodkin,Andre G Skirtach et al.
Saba Taheri et al.
Introduction: Calcium carbonate particles are a very potent type of inorganic drug delivery carrier, which have attractive pH responsiveness, strong mechanical properties, and a relatively high loading capacity. Adding or...
Design and labeling differences between generic and reference listed drug inhalers: human factors considerations in us FDA-approved devices [0.03%]
美国FDA批准的药物吸入器的人机工程学差异考虑：通用和参照药物列表之间的设计和标签差异
Brian D Nguyen,Monifa Vaughn-Cooke
Brian D Nguyen
Background: While generic inhalers are approved based on therapeutic equivalence to their reference listed drug (RLD) counterparts, design and labeling differences may unintentionally affect product usability and patient ...
Carlo Diaferia
Carlo Diaferia
Camille Locht,Keith Rubin
Camille Locht
Introduction: Despite high vaccination coverage, pertussis remains endemic and epidemic cycles continue to occur every 3-5 years, illustrating the shortcomings of current vaccination strategies. Unlike current vaccines, e...
Progress and potential of ferritin nanocages for cancer drug delivery [0.03%]
铁蛋白纳米笼作为癌症药物输送载体的研究进展与潜在价值
Valeria Giacobbo,Francesca Gorgoglione,Marta Sevieri et al.
Valeria Giacobbo et al.
Introduction: Once regarded merely as an iron-storage protein, ferritin is now recognized as a dynamic nanoplatform with significant applications in nanomedicine. By leveraging its intrinsic tropism for tumor cells togeth...
How might intraluminal drug-delivery strategies be improved to enhance arteriovenous fistula maturation and patency? [0.03%]
如何改进腔内药物输送策略以促进动静脉瘘成熟和通畅？
Justin George,Ajit Rao,Alan Dardik
Justin George
Emerging landscape of bioinformatics and artificial intelligence applications in cell-penetrating peptide-based delivery [0.03%]
基于细胞穿透肽的递送系统中生物信息学和人工智能应用的新格局
Yu Sun,Muqing Zhang,Huiting Liu et al.
Yu Sun et al.
Introduction: Peptides play diverse roles in biological processes, including drug discovery, antibacterial activity, and protein-protein interactions, making peptide prediction a crucial field. The development of bioinfor...