Advancing the current state of gene therapies using adeno-associated virus vectors to treat atrial cardiomyopathy [0.03%]
利用腺相关病毒载体的基因治疗技术治疗心房心肌病取得进展
Ahmad Hammoud,Peter Emerson,Natsuki Sasaki et al.
Ahmad Hammoud et al.
Introduction: Atrial cardiomyopathy (ACM) is characterized by complex interactions involving molecular, electrical, and structural abnormalities that predispose individuals to cardiac dysfunction and stroke. Current treat...
Opsonized bilirubin nanomedicine targeting and repolarizing macrophage for acute lung injury treatment [0.03%]
靶向巨噬细胞的溶菌酶结合型胆红素纳米药物用于急性肺损伤治疗
Yinhao Lin,Yanxian Hou,Baiqun Duan et al.
Yinhao Lin et al.
Background: Acute lung injury (ALI) is a pathological condition characterized by diffuse lung injury. Excessive macrophage polarization to the M1 type in lung tissue plays a crucial role in the incidence and aggravation o...
Revolutionizing antiviral therapy: harnessing nanotechnology to unlock the power of phytoconstituents [0.03%]
利用纳米技术开发植物抗病毒成分的抗病毒疗法
Zainab Choonia,Kailash Patil,Trinette Fernandes et al.
Zainab Choonia et al.
Introduction: Viral diseases such as influenza, severe acute respiratory syndrome (SARS) caused due to coronaviruses (CoVs), Ebola, and acquired immunodeficiency syndrome (AIDS) caused due to human immunodeficiency virus ...
Oncofetal chondroitin sulfate in cancer therapy: a promising target for anti-tumor drug delivery? [0.03%]
肿瘤疗法中的癌胎硫酸软骨素：抗肿瘤药物传递的潜在靶点？
Elena Ethel Vidal-Calvo,Ali Salanti
Elena Ethel Vidal-Calvo
Anna Jaromin,Robert Zarnowski,David R Andes et al.
Anna Jaromin et al.
A multimodal perspective to overcome translational barriers in cerebrospinal drug delivery [0.03%]
从多模态角度克服脑脊液药物输送的转化障碍
Christopher Kadamus,Suna Sibi,Reshma Bharadwaj et al.
Christopher Kadamus et al.
Introduction: Translating preclinical findings in human neurological drug delivery remains a challenge, particularly for molecules administered directly into cerebrospinal fluid (CSF) via intrathecal, intracisternal, or i...
Ibrahim M A Hussein,Ilona Krabicová,Gjylije Hoti et al.
Ibrahim M A Hussein et al.
Introduction: Cyclodextrin-based drug delivery systems provide a robust platform for designing targeted nanocarriers that efficiently encapsulate, stabilize, and deliver poorly soluble drugs to specific sites. Their uniqu...
Intra-articular targeted delivery of nanomaterials for the treatment of osteoarthritis: focusing on cell signaling pathway mechanisms [0.03%]
纳米材料的关节腔靶向递送治疗骨关节炎：着眼于细胞信号转导机制
Bo Gu,Jingjing Qi,Xin Li et al.
Bo Gu et al.
Introduction: This review summarizes the application of nanomaterial-mediated intra-articular targeted drug delivery systems in the treatment of osteoarthritis (OA) and their regulatory mechanisms on key cellular signalin...
Targeted delivery of therapeutics to the heart with calcium phosphate nanoparticles [0.03%]
利用钙磷酸盐纳米颗粒靶向投递心脏药物治疗
Camilla Fusacchia,Federica Mancini,Alessio Adamiano et al.
Camilla Fusacchia et al.
Introduction: Cardiovascular diseases (CVDs) remain the leading cause of global mortality, with conventional therapies mainly providing symptomatic relief without targeting underlying molecular and cellular mechanisms. Ad...