Hyaluronic acid-based systems for brain drug delivery: bridging material design and cellular response [0.03%]
基于透明质酸的脑递药系统：材料设计与细胞响应之间的桥梁关系研究
Carla Serri,Mattia Danilo Langellotto,Sanam Gull Arshad et al.
Carla Serri et al.
Introduction: Over the past decade, mucoadhesive polymers have gained increasing attention as key enablers in the development of advanced drug delivery systems for brain therapies. Among them, hyaluronic acid (HA) stands ...
Zinc oxide nanoparticles from drug delivery to immunomodulation: progress and challenges [0.03%]
从药物递送到免疫调节：锌氧化物纳米颗粒的研究进展与挑战
Marzia Conte,Veronica Vighetto,Valentina Cauda
Marzia Conte
Introduction: Over the last decades, zinc oxide nanoparticles (ZnO NPs) have emerged as promising nanoplatforms for various biomedical applications. This critical perspective summarizes the main uses of ZnO NPs in cancer ...
Immunomodulatory strategies and targeted delivery systems in atherosclerosis therapy [0.03%]
动脉粥样硬化治疗中的免疫调控策略和靶向递送系统
Wei Jiang,Huan Tang,Yan Hu et al.
Wei Jiang et al.
Introduction: Atherosclerosis (AS) is a chronic inflammatory disease where lipid-lowering therapy alone leaves 30-40% residual cardiovascular risk, underscoring the need for immunomodulatory interventions. ...
Saving money but costing lives: the lack of integrated dose counters on pressurized metered dose inhalers [0.03%]
节约开支但搭上人命？压差式定量气雾剂缺乏剂量计的问题分析
Francis J Gilchrist,Sadie Clayton,William D Carroll
Francis J Gilchrist
Pressurised metered dose inhalers (pMDIs) are used to deliver treatment to individuals with respiratory diseases. Whilst the technology within pMDIs has not significantly changed in the last 25 years, some changes in legislation and supply ...
Continuous manufacturing of 3D-printed chewable pediatric gummies by coupling hot melt extrusion with direct extrusion additive manufacturing [0.03%]
通过熔融挤出与直接挤出增材制造联用连续生产3D打印咀嚼型儿童口溶片
Siva S Kolipaka,Laura A Junqueira,Vivek Garg et al.
Siva S Kolipaka et al.
Background: 3D printing has been extensively explored as a novel approach to fabricating customized pharmaceuticals due to its adaptability. In this study, a continuous 3D (3-dimensional) printing platform was developed f...
Mechanistic and translational frontiers on "VEGF and TKI inhibitor axitinib": unfolding drug delivery approaches and opportunities in cancer therapy [0.03%]
"关于'VEGF和TKI抑制剂阿昔替尼'的机制及转化前沿：癌症治疗中的给药途径及其机遇"
Divya Sharma,Shiv Kumar Prajapati,Sweta Acharya et al.
Divya Sharma et al.
Introduction: Axitinib demonstrates significant promise in the field of oncology. It effectively inhibits vascular endothelial growth factor (VEGF)-mediated angiogenesis, endothelial proliferation, and tumor microvascular...
Topical film-forming systems for antifungal delivery: emerging strategies and in-depth evaluation [0.03%]
用于抗真菌输送的 topical 成膜系统：新兴策略及深入评价
Siddhi Rawool,Manigandan Thevar,Supriya Shidhaye et al.
Siddhi Rawool et al.
Introduction: Topical film-forming systems (FFSs) are a promising approach for antifungal therapy. After application, the solvent evaporates, leaving a thin polymeric film on the skin. This film acts as a drug reservoir, ...
Peptide amphiphile nanofibers: advanced drug delivery platforms for cardiovascular therapeutics [0.03%]
肽两亲分子纳米纤维：心血管治疗的先进药物递送平台
Katherine I Foley,Adelso Tejada Jackson,Nick D Tsihlis et al.
Katherine I Foley et al.
Introduction: Cardiovascular disease is associated with significant morbidity and mortality worldwide. Current medical and surgical interventions have limitations related to side-effects and long-term efficacy. Hence, the...
Recent and future developments in inhaled formulations to overcome anti-bacterial drug resistance [0.03%]
近期和未来的吸入给药配方发展以克服抗菌药物耐药性问题
Nazrul Islam,Trudi Collet
Nazrul Islam
Introduction: Inhaled antibiotic delivery technology is considered an emerging method for overcoming continual challenges posed by resistant bacteria. It enables the delivery of highly localized drug concentrations, there...
Intravitreal implants for drug delivery: clinical efficacy, safety, and translational perspectives [0.03%]
玻璃体内植入物给药：临床疗效、安全性及转化前景
Carolina Nunes da Silva,Thomas Toshio Inoue,Marina França Dias et al.
Carolina Nunes da Silva et al.
Introduction: Chronic retinal disorders such as age-related macular degeneration, diabetic macular edema, retinal vein occlusion, and noninfectious uveitis are among the leading causes of irreversible visual loss worldwid...