Camille Locht,Keith Rubin
Camille Locht
Introduction: Despite high vaccination coverage, pertussis remains endemic and epidemic cycles continue to occur every 3-5 years, illustrating the shortcomings of current vaccination strategies. Unlike current vaccines, e...
Progress and potential of ferritin nanocages for cancer drug delivery [0.03%]
铁蛋白纳米笼作为癌症药物输送载体的研究进展与潜在价值
Valeria Giacobbo,Francesca Gorgoglione,Marta Sevieri et al.
Valeria Giacobbo et al.
Introduction: Once regarded merely as an iron-storage protein, ferritin is now recognized as a dynamic nanoplatform with significant applications in nanomedicine. By leveraging its intrinsic tropism for tumor cells togeth...
How might intraluminal drug-delivery strategies be improved to enhance arteriovenous fistula maturation and patency? [0.03%]
如何改进腔内药物输送策略以促进动静脉瘘成熟和通畅？
Justin George,Ajit Rao,Alan Dardik
Justin George
Emerging landscape of bioinformatics and artificial intelligence applications in cell-penetrating peptide-based delivery [0.03%]
基于细胞穿透肽的递送系统中生物信息学和人工智能应用的新格局
Yu Sun,Muqing Zhang,Huiting Liu et al.
Yu Sun et al.
Introduction: Peptides play diverse roles in biological processes, including drug discovery, antibacterial activity, and protein-protein interactions, making peptide prediction a crucial field. The development of bioinfor...
Intranasal delivery of lipid-based nanoparticles for the treatment of neurodegenerative diseases: advances, challenges and future perspectives [0.03%]
基于脂质的纳米颗粒鼻内给药治疗神经退行性疾病：进展、挑战与未来展望
Xavier Mulet I Piera,Rubén Del Campo-Montoya,Mar Cuadrado-Tejedor et al.
Xavier Mulet I Piera et al.
Introduction: Neurodegenerative diseases such as Parkinson's or Alzheimer's disease urgently require new therapeutic approaches. Despite significant efforts, no disease-modifying therapies targeting specific molecular pat...
Xiomara Owen,Mohammad Hejazi,Laleh Golshahi
Xiomara Owen
Introduction: Pediatric intranasal (IN) drug delivery is a promising noninvasive way of administering medication, offering a significant improvement over parenteral and oral methods. However, its effectiveness is hindered...
Non-viral mRNA cystic fibrosis therapies and their ongoing clinical trials [0.03%]
非病毒mRNA囊性纤维化疗法及其正在进行的临床试验
Nicole A Gill,Vincent Fung,Rachel VanKeulen-Miller et al.
Nicole A Gill et al.
Introduction: Cystic fibrosis (CF) is a genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, leading to impaired ion transport by the CFTR protein and accumulation of...
Microfluidic-engineered polymeric nanocarriers for targeted drug delivery in liver cancer therapy: part ii recent advances [0.03%]
用于肝癌治疗的靶向给药的微流控工程聚合物纳米载体：第2部分最新进展
Aliakbar Ebrahimiverkiani,Mahboobeh Ebrahimi Varkiani,Maryam Jadid Tavaf et al.
Aliakbar Ebrahimiverkiani et al.
Introduction: Conventional drug delivery systems in cancer therapy face limitations such as poor targeting and adverse side effects. Nanoparticle-based approaches, particularly when integrated with microfluidic technology...
Microfluidic-engineered polymeric nanocarriers for targeted drug delivery in liver cancer therapy: part I principles [0.03%]
肝癌治疗中微流控工程聚类纳米载体给药：第I部分原理
Aliakbar Ebrahimiverkiani,Mahboobeh Ebrahimi Varkiani,Maryam Jadid Tavaf et al.
Aliakbar Ebrahimiverkiani et al.
Introduction: Conventional drug delivery for cancer therapy often suffer from poor targeting efficiency, limited bioavailability, and severe off-target toxicity. Nanoparticle-based approaches have emerged as transformativ...
How can we optimize the delivery of IL-2 to traumatic brain injury patients? [0.03%]
如何优化创伤性脑损伤患者的IL-2输送？
James Dooley,Adrian Liston
James Dooley