Historic demography and phylogenetic relationship of Euthynnus species based on COI sequence analyses [0.03%]
基于COI序列分析的狭腹金枪鱼种类的历史人口学和系统发育关系
Girish Kumar,Swaraj Priyaranjan Kunal
Girish Kumar
Euthynnus species are epipelagic migratory tuna species, with global distribution. They occur in the open waters but usually remain close to the shoreline. In present study, historic demography and phylogenetic relationship of Euthynnus spe...
Performance modelling of parallel BLAST using Intel and PGI compilers on an infiniband-based HPC cluster [0.03%]
基于Intel和PGI编译器的InfiniBand高性能计算集群并行BLAST性能模型研究
Muhammed Al-Mulhem,Raed Al-Shaikh
Muhammed Al-Mulhem
The Basic Local Alignment Search (BLAST) is one of the most widely used bioinformatics programs for searching all available sequence databases for similarities between a protein or DNA query and predefined sequences, using sequence alignmen...
A novel strategy for plant breeding based on simulations of gene network models [0.03%]
基于基因网络模型模拟的植物育种新策略
X Cai,S Das,S M Welch
X Cai
This paper describes a new computational method to make predictions on the outcome of pair-wise crosses of plant lines limiting expensive laboratory breeding experiments to carry out crosses of the most promising pairs of lines. Compared to...
Receptor-based pharmacophore tool for design and development of next-generation drugs [0.03%]
基于受体的药效团工具用于下一代药物的设计和发展
M Udayakumar,Pupala Suresh Kumar,K Hemavathi et al.
M Udayakumar et al.
Drug discovery is an intricate process in which new drugs are designed or discovered. A pharmacophore is an essential ensemble of steric and electronic features for drug discovery, which is necessary to ensure optimal interactions with a sp...
An interval-based algorithm to represent conformational states of experimentally determined polypeptide templates and fast prediction of approximated 3D protein structures [0.03%]
一种基于间隔的算法，用于表示实验确定的多肽模板的构象状态以及快速预测近似的三维蛋白质结构
Márcio Dorn,Osmar Norberto de Souza
Márcio Dorn
Predicting the three-dimensional (3-D) structure of a protein that has no templates in the Protein Data Bank (PDB) is a very hard, still an impossible task. Computational prediction methods have been developed during the last years, but the...
Analysis of oxygen affinity in aquatic amphibian; homology modelling of the major haemoglobin component HbA1 from the African clawed frog (Xenopus laevis, Anura) [0.03%]
非洲爪蟾红细胞血红蛋白的氧亲和力分析及其主要组分HbA1的同源模建研究
Roshan Ali,Ghosia Lutfullah,Abid Ali Khan et al.
Roshan Ali et al.
The homology model of major haemoglobin component HbA1 of the African Clawed Frog was predicted using the pigeon (Columba livia) haemoglobin as a template. The model was built with the help of MODELLER9v8. The models were evaluated with Pro...
Huixiao Hong,Qilong Hong,Jie Liu et al.
Huixiao Hong et al.
A method was proposed for estimating noise relative to signal in microarray data. A signal to noise index, SNI, was defined and used to measure the level of signal compared to the noise contained in two microarray data sets. Simulations wer...
Efficient calculation of compound similarity based on maximum common subgraphs and its application to prediction of gene transcript levels [0.03%]
基于最大公共子图的化合物相似性高效计算及其在预测基因转录水平中的应用
Rogier J P Van Berlo,Wynand Winterbach,Marco J L De Groot et al.
Rogier J P Van Berlo et al.
Properties of a chemical entity, both physical and biological, are related to its structure. Since compound similarity can be used to infer properties of novel compounds, in chemoinformatics much attention has been paid to ways of calculati...
Serial fusion of Random Subspace ensemble for subcellular phenotype images classification [0.03%]
用于亚细胞表型图像分类的随机子空间集成的序列融合方法
Bailing Zhang,Tuan D Pham
Bailing Zhang
Subcellular localisation is a key functional characteristic of proteins. In this paper, we apply Haralick texture analysis and Curvelet Transform for feature description and propose a cascade Random Subspace (RS) ensemble with rejection opt...
Daniel R Hyduke,Evagelia C Laiakis,Heng-Hong Li et al.
Daniel R Hyduke et al.
Ionising radiation is a pleiotropic stress agent that may induce a variety of adverse effects. Molecular biomarker approaches possess promise to assess radiation exposure, however, the pleiotropic nature of ionising radiation induced transc...