In silico analysis, annotation and characterisation of putative ESTs from Sorghum bicolor associated with heat stress [0.03%]
基于Sorghum bicolor与高温胁迫相关的假定EST的计算机分析、注释和特征化
Gobind Ram,Arun Dev Sharma
Gobind Ram
Owing to their sessile nature, plants experience a variety of environmental stresses, but tolerance to these adverse conditions is a very complex phenomenon. Among all stresses, heat stress is the most important constraint that affects plan...
Docking analysis of gallic acid derivatives as HIV-1 protease inhibitors [0.03%]
没食子酸衍生物抗HIV-1蛋白酶的分子对接分析
Anjali Singh,Tapan Kumar Pal
Anjali Singh
HIV-1 Protease (HIV-1 PR) enzymes are essential for accurate assembly and maturation of infectious HIV retroviruses. The significant role of HIV-1 protease in viral replication has made it a potential drug target. In the recent past, phytoc...
Jheyson Faride Vargas,Jairo Andrés Velasco,Gloria Inés Alvarez et al.
Jheyson Faride Vargas et al.
We describe an automatic segmentation method for polyproteins of the viruses belonging to the Potyviridae family. It uses machine learning techniques in order to predict the cleavage site which define the segments in which said polyproteins...
Neural network and rough set hybrid scheme for prediction of missing associations [0.03%]
神经网络和粗糙集混合预测缺失关联规则方案
A Anitha,D P Acharjya
A Anitha
Currently, internet is the best tool for distributed computing, which involves spreading of data geographically. But, retrieving information from huge data is critical and has no relevance unless it provides certain information. Prediction ...
On the interconnection of stable protein complexes: inter-complex hubs and their conservation in Saccharomyces cerevisiae and Homo sapiens networks [0.03%]
关于稳定蛋白质复合物的相互连接：跨复合物中心节点及其在酿酒酵母和人类网络中的保守性
Concettina Guerra
Concettina Guerra
Protein complexes are key molecular entities that perform a variety of essential cellular functions. The connectivity of proteins within a complex has been widely investigated with both experimental and computational techniques. We develope...
Diversity and evolution of the envelope gene of dengue virus type 1 circulating in India in recent times [0.03%]
近年来印度流行的登革病毒1型包膜基因的多样性及进化
Sumanta Dey,Ashesh Nandy,Papiya Nandy et al.
Sumanta Dey et al.
Dengue viral attacks have been reported in various parts of India in recent years. In this paper we report on our studies of the characterisation and evolutionary aspects of gene sequences of the envelope glycoprotein of the prevalent India...
Prashanth Suravajhala,Tiratha Raj Singh
Prashanth Suravajhala
Protein-Protein Interactions (PPI) play a crucial role in deciphering function besides identifying candidates. While the experimental analysis is often time consuming involving number of experiments like pulldown assays, they are not necess...
Opposite nucleotide usage biases in different parts of the Corynebacterium diphtheriae spaC gene [0.03%]
白喉棒状杆菌spaC基因的不同部分存在相反的核苷酸使用偏倚现象
Vladislav Victorovich Khrustalev,Eugene Victorovich Barkovsky,Valentina Leonidovna Kolodkina et al.
Vladislav Victorovich Khrustalev et al.
In this work we described a bacterial open reading frame with two different directions of nucleotide usage biases in its two parts. The level of GC-content in third codon positions (3GC) is equal to 40.17 ± 0.22% during the most of the len...
Receptor-based 3D-QSAR approach to find selectivity features of flexible similar binding sites: case study on MMP-12/MMP-13 [0.03%]
基于受体的三维定量结构活性关系方法寻找柔性相似结合位点的选择性特征：以基质金属蛋白酶-12/13为例研究
Farzin Hadizadeh,Jamal Shamsara
Farzin Hadizadeh
Design of selective matrix metalloproteinases (MMPs) inhibitors is still a challenging task because of binding pocket similarities and flexibility among MMPs family. To overcome this issue we try to generate a (three-dimensional quantitativ...
An interactomic approach for identification of putative drug targets in Listeria monocytogenes [0.03%]
用于鉴定致病菌Listeria monocytogenes药物作用靶点的互作组方法学研究
Nikita Chordia,Nilesh Kumar Sharma,Anil Kumar
Nikita Chordia
A wide variety of human population is infected with Listeria monocytogenes, which causes listeriosis, a deadly disease with mortality rate of about 30%. The major hindrance to cure listeriosis is the unavailability of specific or selectable...