Sequence-based prediction of linear autoepitopes involved in pathogenesis of IPAH and the corresponding organism sources of molecular mimicry [0.03%]
基于序列的预测参与IPAH发病的线性自身表位及其相应的分子模拟生物来源
Jaroslav Kubrycht,Jana Novotná
Jaroslav Kubrycht
We proposed here a sequence-based approach predicting some microorganisms as possible sources of autoantigen-related molecular mimicry concerning Idiopathic Pulmonary Arterial Hypertension (IPAH) and related hypertension mostly accompanying...
A joint framework for missing values estimation and biclusters detection in gene expression data [0.03%]
基因表达数据中联合估计缺失值和检测双聚类的框架
Kin-On Cheng,Ngai-Fong Law,Yui-Lam Chan et al.
Kin-On Cheng et al.
DNA microarray experiment unavoidably generates gene expression data with missing values. This hardens subsequent analysis such as biclusters detection which aims to find a set of co-expressed genes under some experimental conditions. Missi...
An experimental comparison of PMSprune and other algorithms for motif search [0.03%]
PMSprune算法与其他motif搜索算法的实验比较
Dolly Sharma,Sanguthevar Rajasekaran,Sudipta Pathak
Dolly Sharma
A comparative study of the various motif search algorithms is very important for several reasons. For example, we could identify the strengths and weaknesses of each. As a result, we might be able to devise hybrids that will perform better ...
Syed N Mujahid,Dmytro Korenkevych,Panos M Pardalos
Syed N Mujahid
Discovering rare behaviours in stochastic differential equations using decision procedures: applications to a minimal cell cycle model [0.03%]
使用决策过程发现随机微分方程中的罕见行为：最小细胞周期模型的应用
Arup Kumar Ghosh,Faraz Hussain,Susmit Jha et al.
Arup Kumar Ghosh et al.
Stochastic Differential Equation (SDE) models are used to describe the dynamics of complex systems with inherent randomness. The primary purpose of these models is to study rare but interesting or important behaviours, such as the formation...
Parameter discovery in stochastic biological models using simulated annealing and statistical model checking [0.03%]
使用模拟退火和统计模型检测在随机生物模型中的参数发现
Faraz Hussain,Sumit K Jha,Susmit Jha et al.
Faraz Hussain et al.
Stochastic models are increasingly used to study the behaviour of biochemical systems. While the structure of such models is often readily available from first principles, unknown quantitative features of the model are incorporated into the...
Finding consensus stable local optimal structures for aligned RNA sequences and its application to discovering riboswitch elements [0.03%]
一类RNA序列对准的局部最优结构及其在寻找核酶开关中的应用
Yuan Li,Cuncong Zhong,Shaojie Zhang
Yuan Li
Many non-coding RNAs (ncRNAs) can fold into alternate native structures and perform different biological functions. The computational prediction of an ncRNA's alternate native structures can be conducted by analysing the ncRNA's energy land...
Discovering non-coding RNA elements in Drosophila 3' untranslated regions [0.03%]
果蝇3'非翻译区非编码RNA元件的发现
Cuncong Zhong,Justen Andrews,Shaojie Zhang
Cuncong Zhong
The Non-Coding RNA (ncRNA) elements in the 3' Untranslated Regions (3'-UTRs) are known to participate in the genes' post-transcriptional regulations. Inferring co-expression patterns of the genes through clustering these 3'-UTR ncRNA elemen...
Mapping genomic features to functional traits through microbial whole genome sequences [0.03%]
通过微生物全基因组序列将基因组特征映射到功能表型中
Wei Zhang,Erliang Zeng,Dan Liu et al.
Wei Zhang et al.
Recently, the utility of trait-based approaches for microbial communities has been identified. Increasing availability of whole genome sequences provide the opportunity to explore the genetic foundations of a variety of functional traits. W...
Andrew Thrasher,Zachary Musgrave,Brian Kachmarck et al.
Andrew Thrasher et al.
Next generation sequencing technologies have enabled sequencing many genomes. Because of the overall increasing demand and the inherent parallelism available in many required analyses, these bioinformatics applications should ideally run on...