Abdur Rahman Sikder,Albert Y Zomaya
Abdur Rahman Sikder
The importance of protein folding has been recognised for many years. Almost a half century ago, Linus Pauling discovered two quite simple, regular arrangements of amino acids--the alpha-helix and the beta-sheet that are found in almost eve...
K Najarian,K Gopalakrishnan,R H Zadeh
K Najarian
We present a new technique to predict the functional behaviour of protein mutants using their primary sequence. The amino acid sequences of proteins are used to form biochemical signals. Signal processing techniques are used to extract func...
Xiaohua Hu
Xiaohua Hu
Protein-protein interaction network is essential to understand the fundamental processes that govern cell biology. In this paper, we integrate information extraction and data mining techniques to extract and mine the scale-free protein-prot...
BioStar models of clinical and genomic data for biomedical data warehouse design [0.03%]
临床和基因组数据的BioStar模型在生物医学数据仓库设计中的应用研究
Liangjiang Wang,Aidong Zhang,Murali Ramanathan
Liangjiang Wang
Biomedical research is now generating large amounts of data, ranging from clinical test results to microarray gene expression profiles. The scale and complexity of these datasets give rise to substantial challenges in data management and an...
A three-stage framework for gene expression data analysis by L1-norm support vector regression [0.03%]
基于L1范数支持向量回归的基因表达数据分析三步框架
Hyunsoo Kim,Jeff X Zhou,Herbert C Morse rd et al.
Hyunsoo Kim et al.
The identification of discriminative genes for categorical phenotypes in microarray gene expression data analysis has been extensively studied, especially for disease diagnosis. In recent biological experiments, continuous phenotypes have a...
Suman Sundaresh,She-pin Hung,G Wesley Hatfield et al.
Suman Sundaresh et al.
This paper analyses variability in highly replicated measurements of DNA microarray data conducted on nylon filters and Affymetrix GeneChips with different cDNA targets, filters, and imaging technology. Replicability is assessed quantitativ...
Dynamic visual data mining: biological sequence analysis and annotation using SeqVISTA [0.03%]
动态视觉数据分析及使用SeqVISTA的生物序列分析及注释
Tianhua Niu,Zhenjun Hu
Tianhua Niu
In the post-genomic era, the volume of public sequence databases is increasing exponentially and visualisation-centric techniques have become more and more important in biological sequence analysis and annotation. In this paper, we present ...
Wojciech Szpankowski,Wenhui Ren,Lukasz Szpankowski
Wojciech Szpankowski
The biological world is highly stochastic and inhomogeneous in its behaviour. There are regions in DNA with a high concentration of G or C bases; stretches of sequences with an abundance of CG dinucleotide (CpG islands); coding regions with...