Matthew J Zukoski,Terrance Boult,Tunç Iyriboz
Matthew J Zukoski
As medical/biological imaging facilities move towards complete film-less imaging, compression plays a key role. Although lossy compression techniques yield high compression rates, the medical community has been reluctant to adopt these meth...
J K Kalita,K Chandrashekar,R Hans et al.
J K Kalita et al.
We have developed a software system called SIMISYS that models and simulates aspects of the human immune system based on the computational framework of cellular automata. We model tens of thousands of cells as exemplars of the significant p...
Janet Siebert,Krzysztof J Cios,M Karen Newell
Janet Siebert
Existing analysis tools for flow cytometry data offer specialised but limited functionality. This work presents advantages of combining the cytometer's data with sample-specific information. Data is loaded into a relational database, where ...
Discriminating TATA box from putative TATA boxes in plant genome [0.03%]
植物基因组中TATA盒与其假阳性位点的识别区分方法研究
Raja Loganantharaj
Raja Loganantharaj
The TATA box has been used successfully to identify a transcription start site (TSS) and thereby a promoter. Unfortunately, there are many substrings which fit the profile of a TATA box and such substrings are called putative TATA boxes. We...
Jesse Mecham,Mark Clement,Quinn Snell et al.
Jesse Mecham et al.
Phylogenetic analysis is a central tool in studies of comparative genomics. When a new region of DNA is isolated and sequenced, researchers are often forced to throw away months of computation on an existing phylogeny of homologous sequence...
B M Broom,T J McDonnell,D Subramanian
B M Broom
Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simply list a set of differentially expressed genes. We propose a ...
Experimental analysis of a new algorithm for partial haplotype completion [0.03%]
一种新的用于部分单体型补齐算法的实验分析
Paola Bonizzoni,Gianluca Della Vedova,Riccardo Dondi et al.
Paola Bonizzoni et al.
This paper deals with the computational problem of inferring complete information on haplotypes from haplotypes with missing data. This problem is one of the main issues in haplotyping, as the current DNA sequencing technology often produce...
Wavelet transformation and cluster ensemble for gene expression analysis [0.03%]
小波变换和聚类分析在基因表达中的应用研究
Xiaohua Hu,Illhoi Yoo,Xiaodan Zhang et al.
Xiaohua Hu et al.
This paper introduces a wavelet transformation and a cluster ensemble framework using graph theory for clustering gene expression data sets. The experiment results indicate that wavelet transformation and cluster ensemble approaches togethe...
Reconstructing phylogenetic trees of prokaryote genomes by randomly sampling oligopeptides [0.03%]
通过随机采样寡肽重构原核生物基因组的系统发育树
Osamu Maruyama,Akiko Matsuda,Satoru Kuhara
Osamu Maruyama
In this paper, we propose a method for reconstructing phylogenetic trees of a given set of prokaryote organisms by randomly sampling relatively small oligopeptides of a fixed length from their complete proteomes. For each of the organisms, ...
Protein secondary structure prediction by combining hidden Markov models and sliding window scores [0.03%]
结合隐马尔可夫模型与滑动窗口评分的蛋白质二级结构预测方法
Wei-Mou Zheng
Wei-Mou Zheng
Instead of conformation states of single residues, refined conformation states of quintuplets are proposed to reflect conformation correlation. Simple hidden Markov models combined with sliding window scores are used to predict the secondar...