A grid-based pseudo-cache solution for MISD biomedical problems with high confidentiality and efficiency [0.03%]
一种用于高保密高效MISD生物医学问题的基于网格的伪缓存方案
Yuan-Shun Dai,Mathew Palakal,Shielly Hartanto et al.
Yuan-Shun Dai et al.
The complexity of most biomedical/bioinformatics problems requires efficient solutions using collaborative/parallel computing. One promising solution is to implement Grid computing, as an emerging new field called BioGrid. However, one of t...
Identification of hair cycle-associated genes from time-course gene expression profile using fractal analysis [0.03%]
利用分形分析鉴定与毛囊周期相关的基因
Sunil K Mathur,Atul M Doke,Ajit Sadana
Sunil K Mathur
Microarray technology permits one to monitor thousands of processes going on inside the cell. This tool has been used to study gene expression profiles associated with the hair-growth cycle. We provide a novel method called the fractal anal...
Phylogenetic analysis using complete signature information of whole genomes and clustered Neighbour-Joining method [0.03%]
基于全基因组完整签名信息的谱系分析及聚类邻接法
Xiaomeng Wu,Xiu-Feng Wan,Gang Wu et al.
Xiaomeng Wu et al.
A new method called Complete Composition Vector (CCV), which is a collection of Composition Vectors (CV), is described to infer evolutionary relationships between species using their complete genomic sequences. Such a method bypasses the co...
Multiple testing in large-scale contingency tables: inferring patterns of pair-wise amino acid association in beta-sheets [0.03%]
大规模列联表中的多重比较：推断β-折叠中成对氨基酸关联模式
Seoung Bum Kim,Kwok-Leung Tsui,Mark Borodovsky
Seoung Bum Kim
This study examines the feasibility of using multiple testing procedures for an inference of independence of categories in each cell in contingency tables. In the simulation study, we compare the performance of various multiple testing proc...
Tuan D Pham
Tuan D Pham
Microarray gene expression data provide life science researchers with much more sensitive and detailed information about gene expression patterns than conventional methodologies for the purpose of facilitating gene recognition efforts. Howe...
Magnitude and spatial orientation of the hydrophobic moments of multi-domain proteins [0.03%]
多结构域蛋白质疏水矩的大小和空间取向
Ruhong Zhou,Ajay Royyuru,Prasanna Athma et al.
Ruhong Zhou et al.
The distributions of residue hydrophobicity for individual domains as well as for the aggregates of domains on a single chain have been found to exhibit well-defined second-order hydrophobic moment profiles. This indicates that most of the ...
Guohui Lin,Xiang Wan,Theodore Tegos et al.
Guohui Lin et al.
This paper proposes a novel statistical evaluation model for automated protein NMR sequential resonance assignment. It can be bound to any assignment program and provides confidences for the whole output assignment and each individual mappi...
Shibin Qiu,Terran Lane
Shibin Qiu
RNA interference (RNAi) is a posttranscriptional gene silencing mechanism used to study gene functions, knock down viral genes, and treat diseases therapeutically. However, an 'off-target effect' deteriorates its specificity and applicabili...
Scott F Smith
Scott F Smith
Protein homology search can be accelerated with the use of bit-parallel algorithms in conjunction with constraints on the values contained in the scoring matrices. Trinary scoring matrices (containing only the values -1, 0, and 1) allow for...
Protein sub-cellular localisation prediction by analysis of short-range residue correlations [0.03%]
基于短程残基相关性的蛋白质亚细胞定位预测方法研究
Jian Guo,Yuanlie Lin,Zhirong Sun
Jian Guo
Sub-cellular localisation performs an important role in genome analysis. This paper describes a new residue-couple model using a support vector machine to predict the sub-cellular localisation of proteins. This new approach provides better ...