ASFinder: a tool for genome-wide identification of alternatively splicing transcripts from EST-derived sequences [0.03%]
ASFinder：一个从EST衍生序列鉴定全基因组选择性剪切转录本的工具
Xiang Jia Min
Xiang Jia Min
Expressed Sequence Tags (ESTs) are a rich resource for identifying Alternatively Splicing (AS) genes. The ASFinder webserver is designed to identify AS isoforms from EST-derived sequences. Two approaches are implemented in ASFinder. If no g...
Prediction of protein secondary structure using Large Margin Nearest Neighbour classification [0.03%]
基于广义边际最近邻分类的蛋白质二级结构预测
Wei Yang,Kuanquan Wang,Wangmeng Zuo
Wei Yang
In this paper, we introduce a novel method for protein secondary structure prediction by using Position-Specific Scoring Matrices (PSSM) profiles and Large Margin Nearest Neighbour (LMNN) classification. Since the PSSM profiles are not spec...
Discovering novel carriers for oral insulin tablets: a pharmacoinformatics approach [0.03%]
一种用于口服胰岛素片的新型载体的药理信息学方法发现研究
R Seenivasagam,K Hemavathi,G Sivakumar et al.
R Seenivasagam et al.
Insulin is used medically to treat Type 1 diabetes mellitus most commonly injected subcutaneously for human beings. The realisation that insulin injections have become a part of life can be extremely harrowing for many diabetic patients. Us...
Evaluation of gene ontology semantic similarities on protein interaction datasets [0.03%]
评估基因本体语义相似性在蛋白质相互作用数据集上的表现
Gang Chen,Jianhuang Li,Jianxin Wang
Gang Chen
Background: Because of the importance of protein interactions in organisms, researchers are interested in the functional similarity between interacted proteins. Gene ontology semantic similarity provides a novel way to me...
Identification of motor imagery tasks through CC-LR algorithm in brain computer interface [0.03%]
基于CC-LR算法的脑机接口中运动想象任务识别
Siuly,Yan Li,Peng Wen
Siuly
This study focuses on the identification of Motor Imagery (MI) tasks for the development of Brain Computer Interface (BCI) technologies combining Cross-Correlation and Logistic Regression (CC-LR) techniques. The proposed method is tested on...
A parallel strategy for predicting the secondary structure of polycistronic microRNAs [0.03%]
一种预测多顺反子microRNA二级结构的并行策略
Dianwei Han,Guiliang Tang,Jun Zhang
Dianwei Han
The biogenesis of a functional microRNA is largely dependent on the secondary structure of the microRNA precursor (pre-miRNA). Recently, it has been shown that microRNAs are present in the genome as the form of polycistronic transcriptional...
Anasua Sarkar,Macha Nikolski,Pascal Durrens
Anasua Sarkar
In this paper we propose an automatic protein family expansion approach for recruitment of new members among the protein-coding genes in newly sequenced genomes. The criteria for adding a new member to a family depends on the structure of e...
Meropenem: a potent drug against superbug as unveiled through bioinformatics approaches [0.03%]
美罗培南：通过生物信息学方法发现的一种对抗超级细菌的强力药物
Medhavi Mallick,Devang Odedra,Ambarish Sharan Vidyarthi et al.
Medhavi Mallick et al.
Global spread of multi-drug resistant bacteria like Klebsiella pneumoniae and Escherichia coli have raised the alarm for researchers and doctors throughout the world. This new mechanism of resistance and the ability of ndm-1 gene to be tran...
Steve S H Ling,Hung Nguyen,H K Lam
Steve S H Ling
Automatic data analysis of real-time song and locomotor activity in zebra finches [0.03%]
用于研究斑胸草雀实时歌曲和运动行为的自动数据分析系统
Susanne L T Cappendijk,Geoffery L Miller,Patrick L Yount et al.
Susanne L T Cappendijk et al.
The zebra finch is a superb natural animal model to study cognition and as such could contribute to the further understanding of nicotinic intervention therapies for patients suffering from cognitive impairment as observed in neurodegenerat...