In silico analysis of putative miRNAs and their target genes in sorghum (Sorghum bicolor) [0.03%]
低分子量果胶对CCl4诱导的急性肝损伤小鼠的保护作用及机制研究
Gobind Ram,Arun Dev Sharma
Gobind Ram
MicroRNAs (miRNAs) are small endogenous genes regulators which regulate different processes underlying plant adaptation to abiotic stresses. To gain a deep understanding of role of miRNAs in plants, in the present study, we computationally ...
Exploitation of in silico potential in prediction, validation and elucidation of mechanism of anti-angiogenesis by novel compounds: comparative correlation between wet lab and in silico data [0.03%]
新型抗血管生成化合物的体内体外数据对比研究及其机制探讨
Jamal M Arif,M Haris Siddiqui,Salman Akhtar et al.
Jamal M Arif et al.
This study describes in silico validation of the wet lab data from aeroplysinin-1, curcumin and halofuginone using Autodock Tools 4.0. The inhibition patterns of the vascular endothelial cell differentiation and capillary tube formation med...
A new greedy randomised adaptive search procedure for Multiple Sequence Alignment [0.03%]
求解多序列比对问题的新型贪婪随机自适应搜索算法
Abdesslem Layeb,Marwa Selmane,Maroua Bencheikh Elhoucine
Abdesslem Layeb
The Multiple Sequence Alignment (MSA) is one of the most challenging tasks in bioinformatics. It consists of aligning several sequences to show the fundamental relationship and the common characteristics between a set of protein or nucleic ...
In silico analysis of mt 16S rRNA sequences of ocypodid crabs [0.03%]
ocypodid螃蟹的mt 16S rRNA序列的计算机分析方法研究
Nirmal K Prasad,Vaibhav Vindal
Nirmal K Prasad
The family Ocypodidae comprises of four sub-families Dotillinae, Heloeciinae, Macrophthalminae and Ocypodinae. Ocypodidae mt 16S rRNA sequences were analysed for studying the conserved regions and phylogeny. Conserved regions will be helpfu...
Cytochrome Oxidase I (COI) sequence conservation and variation patterns in the yellowfin and longtail tunas [0.03%]
黄鳍金枪鱼和长鳍金枪鱼细胞色素氧化酶亚基Ⅰ(COI)序列的保守性和变异模式分析
Swaraj Priyaranjan Kunal,Girish Kumar
Swaraj Priyaranjan Kunal
Tunas are commercially important fishery worldwide. There are at least 13 species of tuna belonging to three genera, out of which genus Thunnus has maximum eight species. On the basis of their availability, they can be characterised as ocea...
Liliana López-Kleine,Nicolás Molano,Luis Ospina
Liliana López-Kleine
Since the introduction of genome sequencing techniques several methods for genomic data preprocessing and analysis have been published and applied to answer different biological questions. Rarely, multivariate methods have been used to extr...
Jinyan Huang
Jinyan Huang
Protein phosphorylation plays a fundamental role in most of the cellular regulatory pathways. Experimental identification of phosphorylation sites is labour-intensive and often limited by the availability and optimisation of enzymatic react...
A discrete search algorithm for finding the structure of protein backbones and side chains [0.03%]
一种用于寻找蛋白质主链和侧链结构的离散搜索算法
Silas Sallaume,Simone de Lima Martins,Luiz Satoru Ochi et al.
Silas Sallaume et al.
Some information about protein structure can be obtained by using Nuclear Magnetic Resonance (NMR) techniques, but they provide only a sparse set of distances between atoms in a protein. The Molecular Distance Geometry Problem (MDGP) consis...
Predicting pathologic complete response to neoadjuvant chemotherapy in breast cancer using sparse logistic regression [0.03%]
使用稀疏逻辑回归预测新辅助化疗在乳腺癌中的病理完全缓解
Wei Hu
Wei Hu
We utilised Sparse Logistic Regression (SLR) to build two sparse and interpretable predictors. The first one (SLR-65) was based on a signature consisting of the top 65 probe sets (59 genes) differentially expressed between Pathologic Comple...
Analysis of non-synonymous single-nucleotide polymorphisms and population variability of PLD2 gene associated with hypertension [0.03%]
PLD2基因的非同义单核苷酸多态性及高血压相关人群变异分析
Arpita Kundu,Parvathy Ramakrishnan,Ambika Rajendran et al.
Arpita Kundu et al.
We have determined the non-synonymous Single-Nucleotide Polymorphisms (nsSNPs) of PLD2 gene and its variations in different populations to understand its role in hypertension. Out of 350 SNPs, six are found to be non-synonymous, of which tw...