Crystallization of the HigBA2 toxin-antitoxin complex from Vibrio cholerae [0.03%]
霍乱弧菌HigBA2 毒素-抗毒素复合物的晶体结构解析
San Hadži,Abel Garcia-Pino,Sergio Martinez-Rodriguez et al.
San Hadži et al.
The genome of Vibrio cholerae encodes two higBA toxin-antitoxin (TA) modules that are activated by amino-acid starvation. Here, the TA complex of the second module, higBA2, as well as the C-terminal domain of the corresponding HigA2 antitox...
Crystallization and preliminary X-ray diffraction analysis of human importin β-Snail zinc finger domain complex [0.03%]
人进口β-Snail锌指结构域复合物的结晶及初步X射线衍射分析
Saehae Choi,Jinsue Song,Se-Young Son et al.
Saehae Choi et al.
Snail is a C2H2-type zinc finger transcriptional repressor that induces epithelial-mesenchymal transition by repression of E-cadherin expression levels during embryonic development and tumour progression. Snail is imported into the nucleus ...
Fibronectin type III domains engineered to bind CD40L: cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of two complexes [0.03%]
用于结合CD40L的纤维连接蛋白III工程结构域：两个复合物的克隆、表达、纯化、结晶及初步X射线衍射分析
Vaheh Oganesyan,Andrew Ferguson,Luba Grinberg et al.
Vaheh Oganesyan et al.
Tn3 proteins are a novel class of binding molecules based on the third fibronectin type III domain of human tenascin C. Target-specific Tn3 proteins are selected from combinatorial libraries in which three surface-exposed loops have been di...
Expression, crystallization and preliminary X-ray crystallographic analysis of alanine racemase from Acinetobacter baumannii OXA-23 [0.03%]
鲍曼不动杆菌OXA-23型丙氨酸消旋酶的表达、结晶及初步X射线晶体学分析
Dinh-Duc Nguyen,Ho-Phuong-Thuy Ngo,Myoung-ki Hong et al.
Dinh-Duc Nguyen et al.
Acinetobacter baumannii has received much attention owing to its exceptional ability to develop resistance to currently available antibiotics. Alanine racemase (ALR) catalyzes the racemization of L-alanine to D-alanine with pyridoxal 5'-pho...
Expression, crystallization and preliminary X-ray crystallographic analysis of alcohol dehydrogenase (ADH) from Kangiella koreensis [0.03%]
来自Kangiella koreensis的酒精脱氢酶（ADH）的表达、结晶及其初步X射线晶体学分析
Ho-Phuong-Thuy Ngo,Seung-Hye Hong,Myoung-Ki Hong et al.
Ho-Phuong-Thuy Ngo et al.
Alcohol dehydrogenases (ADHs) are a group of dehydrogenase enzymes that facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of NAD(+) to NADH. In bacteria, some alcohol dehydrogenases catalyze the opp...
Purification, crystallization and preliminary X-ray analysis of adenylosuccinate synthetase from the fungal pathogen Cryptococcus neoformans [0.03%]
从新型隐球菌中纯化、结晶及腺苷琥珀酸合成酶的初步X射线分析
Ross D Blundell,Simon J Williams,Carl A Morrow et al.
Ross D Blundell et al.
With increasingly large immunocompromised populations around the world, opportunistic fungal pathogens such as Cryptococcus neoformans are a growing cause of morbidity and mortality. To combat the paucity of antifungal compounds, new drug t...
Cloning, expression, purification and preliminary X-ray analysis of the dimerization domain of ethylene response sensor 1 (ERS1) from Arabidopsis thaliana [0.03%]
拟南芥乙烯响应传感器1(ERS1)二聚化结构域的克隆、表达、纯化及初步X射线分析
Hubert Mayerhofer,Jochen Mueller-Dieckmann
Hubert Mayerhofer
Ethylene signalling is initiated by a group of membrane-bound receptors with similarity to two-component systems. ERS1 belongs, together with ETR1, to subfamily 1, which plays a predominant role in ethylene signalling. The dimerization doma...
Preliminary X-ray crystallographic studies of the TRAF domain of human TRAF4 [0.03%]
人TRAFTRAF4的TRAF结构域的初步X射线晶体学研究
Jong Hwan Yoon,Hyun Ho Park
Jong Hwan Yoon
TNF receptor-associated factor (TRAF) proteins were initially identified as tumour necrosis factor receptor (TNFR)-interacting proteins that perform critical functions in the regulation of inflammation, antiviral responses and apoptosis. Al...
Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2.3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes [0.03%]
来自侵袭性M3族链球菌的Scl2.3（一种链球菌胶原样蛋白）可变区的结晶及初步X射线晶体学分析
Flavia Squeglia,Beth Bachert,Maria Romano et al.
Flavia Squeglia et al.
Streptococcal collagen-like proteins (Scls) are widely expressed by the well recognized human pathogen Streptococcus pyogenes. These surface proteins contain a signature central collagen-like region and an amino-terminal globular domain, te...
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of human myosin 1c in complex with calmodulin [0.03%]
人源肌球蛋白1C-钙调蛋白复合物的表达、纯化、结晶及初步X射线衍射分析
Stefan Münnich,Dietmar J Manstein
Stefan Münnich
Myosin 1c (Myo1c) is implicated in several cellular processes such as vesicle transport and the mediation of adaptation in the inner ear. Consequently, mutations impairing Myo1c motor activity lead to hearing loss in humans. To understand t...