The role of cardiac imaging for diagnosis of cardiac amyloidosis: a systematic review and meta-analysis of test accuracy [0.03%]
心脏影像学在诊断心脏淀粉样变性中的作用：一项系统评价和检验准确度的meta分析
Hassan Kawtharany,Muayad Azzam,Jamil Nazzal et al.
Hassan Kawtharany et al.
Objective: To evaluate the diagnostic test accuracy of cardiac magnetic resonance (CMR) and echocardiography for diagnosis of cardiac involvement in patients with biopsy proven light-chain (AL) amyloidosis. ...
Detection yield of surrogate tissue biopsies across amyloidosis classes: a large-scale analysis of 4,027 patients [0.03%]
四种组织活检在不同类型的淀粉样变性疾病中的阳性检测率：一项针对4027例患者的大型研究分析
Natasha J Burke,Lisa M Mendelson,Tracy Joshi et al.
Natasha J Burke et al.
Background: Congo red (CR) staining of surrogate tissues, such as the abdominal fat pad (FP) or bone marrow (BM), provides a minimally invasive approach to diagnosing systemic amyloidosis. This study evaluated the diagnos...
ALyzer3D.AI: a more generalizable deep learning predictor of light chain amyloidogenicity powered by structural and evolutionary Artificial Intelligence [0.03%]
ALyzer3D.AI：一种由结构和进化人工智能驱动的更通用的深度学习轻链淀粉样蛋白生成预测器
Peter May,Johannes Jung,Marion Högner et al.
Peter May et al.
Background: Predicting amyloidogenic risk of immunoglobulin light chains in amyloid light-chain (AL) amyloidosis is a major challenge, and existing computational models fail to generalize to new patient data. ...
Untwisted amyloid fibrils from a transgenic mouse model of AL amyloidosis [0.03%]
来自AL型淀粉样变性转基因小鼠模型的未扭曲淀粉样原纤维
Luca Broggini,Diane Marie Valérie Bonnet,Karolina W Swiderska et al.
Luca Broggini et al.
Endothelial glycocalyx disruption and early renal tubular injury in hereditary transthyretin Amyloidosis with dysautonomia [0.03%]
遗传性转甲状腺素蛋白淀粉样变性和自主神经病变的内皮糖萼破坏和早期肾小管损伤
Lara Albuquerque de Brito,Cleonisio Leite Rodrigues,Alexandre Braga Libório et al.
Lara Albuquerque de Brito et al.
Frontline Dara-CyBorD for AL amyloidosis: high response rates and cytogenetic insights from a real-world cohort [0.03%]
达拉他滨-硼替佐米-Dex治疗AL淀粉样变性：真实世界队列的高反应率和细胞遗传学启示
Xia Wu,Eugène Brailovski,Denis Toskic et al.
Xia Wu et al.
Per Westermark
Per Westermark
Limited diagnostic utility of systematic Congo red staining in bone marrow biopsies [0.03%]
系统性刚果红骨髓活检的有限诊断作用
Jens Haugbølle Bjerre
Jens Haugbølle Bjerre
Single-slide detection and typing of AL renal amyloidosis: combining mass spectrometry imaging and digital pathology [0.03%]
单片检测和分型AL肾淀粉样变性：结合质谱成像和数字病理学
Greta Bindi,Giorgio Cazzaniga,Federico Alberici et al.
Greta Bindi et al.
Background: Amyloid typing, particularly in monoclonal gammopathies of renal significance, can be technically challenging. Matrix-Assisted Laser Desorption/Ionisation-Mass Spectrometry Imaging (MALDI-MSI) has been propose...
Optimized methods for efficient application of immunogold electron microscopy to amyloid fibrils typing [0.03%]
高效利用免疫电子显微镜法进行淀粉样纤维分型的方法学优化
Yan Zhou,Weining Lu,Eric Burks et al.
Yan Zhou et al.
Objective: Amyloidosis is a group of disorders characterized by aggregation of abnormal amyloid protein in various tissues, often leading to organ dysfunction and failure. We optimized the immunogold electron microscopy (...