Accelerated apolipoprotein A-II senile amyloidosis in a plasminogen activator inhibitor-1 knock-out model [0.03%]
Gilles R Codo,Pauline Duchatelet,Gemma Martinez-Rivas et al.
Gilles R Codo et al.
Transthyretin stabilizer therapy increases naturally-occurring antibodies in ATTR cardiomyopathy [0.03%]
转甲状腺素蛋白稳定剂治疗可增加ATTR心肌病患者自然产生的自身抗体
Stephan Settelmeier,Daniel Agranovski,Maximilian Steinhardt et al.
Stephan Settelmeier et al.
Background: Amyloid transthyretin cardiomyopathy (ATTR-CM) results from extracellular deposition of misfolded transthyretin (TTR), causing progressive heart failure. Naturally-occurring antibodies (nAbs) targeting misfold...
Incidence of second primary malignancies in patients with AL amyloidosis and the impact of disease stage and therapies [0.03%]
轻链型淀粉样变性患者继发恶性肿瘤的发病情况及其对疾病分期和治疗方式的影响
Efstathios Kastritis,Vassiliki Spiliopoulou,Foteini Theodorakakou et al.
Efstathios Kastritis et al.
Development and validation of the modified-comprehensive Kumamoto Score: a multi-organ assessment tool for hereditary transthyretin amyloidosis [0.03%]
改良版金泽评分的制定和验证：一种遗传性转甲状腺素蛋白淀粉样变性的多器官评估工具
Shiori Yamakawa,Toshiya Nomura,Yohei Misumi et al.
Shiori Yamakawa et al.
Background: Disease-modifying therapies for hereditary transthyretin (ATTRv) amyloidosis necessitate sensitive, multi-organ assessment tools capturing early disease manifestations across heterogeneous phenotypes. We devel...
Serum peripherin as a disease biomarker in hereditary transthyretin amyloidosis: a multicenter cohort study [0.03%]
遗传性转甲状腺素蛋白淀粉样变性的疾病生物标志物外周蛋白抗体：一项多中心队列研究
Domenico Plantone,Delia Righi,Angela Romano et al.
Domenico Plantone et al.
Background: Hereditary transthyretin amyloidosis (ATTRv, v for variant) is a rare, progressive, and fatal multisystemic disease. Peripherin represents a promising biomarker for axonal damage in the peripheral nervous syst...
Clinical impact of lilac-colored aggregates on may-Grünwald-Giemsa-stained bone marrow smears in patients with amyloid light-chain amyloidosis [0.03%]
吉姆萨染色骨髓涂片中紫色颗粒对轻链型淀粉样变患者的影响临床影响
Ayaka Kodama,Ritsuko Nakagoshi,Ryuto Oshita et al.
Ayaka Kodama et al.
Background: Lilac-colored aggregates (LicAGs) are often observed on bone marrow (BM) aspirate smears stained with May-Grünwald-Giemsa (MG) in patients with amyloid light-chain (AL) amyloidosis. However, the clinicopathol...
Lysozyme encounters transthyretin: rethinking amyloid complexity in ligamentum flavum [0.03%]
弹性蛋白酶遇到转运蛋白：对黄韧带淀粉样复杂性的新认识
Mitsuharu Ueda
Mitsuharu Ueda
Systemic fibrinogen Aα-chain amyloidosis in Manchester Terrier dogs [0.03%]
Manchester terrier犬全身Aα链纤维蛋白原淀粉样变性
Natsumi Kobayashi,Keiichi Kuroki,Yoshiyuki Itoh et al.
Natsumi Kobayashi et al.
Early cardiac sympathetic denervation in hereditary transthyretin amyloidosis: 123I-metaiodobenzylguanidine findings and correlation with skin biopsy [0.03%]
遗传性transthyretin淀粉样变性早期心脏交感神经破坏的发现：碘-123间位碘苯基呱啶检查结果及与皮肤活检的相关性研究
Viviana Frantellizzi,Chiara Cambieri,Eleonora Galosi et al.
Viviana Frantellizzi et al.
Background: Hereditary transthyretin amyloidosis (ATTRv) is a multisystem disorder caused by misfolded TTR deposition, leading to neuropathy and cardiomyopathy. Early identification of subclinical involvement remains diff...
Lysozyme as an amyloid fibril protein together with transthyretin in the ligamentum flavum in association with lumbar spinal stenosis [0.03%]
腰椎管狭窄与弹力韧带中溶菌酶和转运蛋白一起作为淀粉样纤维蛋白的一种形式的关系研究
Gunilla Westermark,Svante Berg,Per Eldhagen et al.
Gunilla Westermark et al.
Background: Transthyretin amyloid (ATTR) is frequently found in aging ligaments and may represent an early sign of systemic ATTR amyloidosis, particularly of wild-type origin. Amyloid deposits of other compositions are co...