Ongoing or halted amyloid deposition in systemic amyloidosis: essential to know early, but which tools may give early insight? [0.03%]
系统性淀粉样变性中的进行性和停止性淀粉样物质沉积：尽早了解至关重要，但哪些工具可以提供早期线索？
Bouke P C Hazenberg,Bart-Jan Kroesen,Johan Bijzet et al.
Bouke P C Hazenberg et al.
Proteolysis reconciles inconsistencies found in proteomic and cryo-EM studies of ATTR [0.03%]
蛋白酶解技术解决了ATTR蛋白组学和冷冻电镜研究中的不一致问题
Avi Chakrabartty
Avi Chakrabartty
Clarifying the immunoglobulin light chain variable gene usage in Chinese patients with renal AL amyloidosis [0.03%]
中国肾AL型淀粉样变患者轻链可变区基因使用的澄清研究
Shuang Wang,Dan-Yang Li,Dan Liu et al.
Shuang Wang et al.
Background: The association between immunoglobulin light chain variable (IGVL) gene usage and clinicopathological features in renal AL amyloidosis requires further research. This study analyzed IGVL genes and their associ...
Haemorrhagic events in patients with transthyretin cardiac amyloidosis [0.03%]
转甲状腺素蛋白心肌淀粉样变患者出血事件的危险因素分析
Lucía Moreno De Redrojo Cortés,Rocío Eiros Bachiller,Eduardo Villacorta Argüelles et al.
Lucía Moreno De Redrojo Cortés et al.
Background: transthyretin cardiac amyloidosis (ATTR-CA) is an infiltrative disease associated with several comorbidities such as Bleeding. The aim of this study was to evaluate the incidence of bleeding in patients with A...
Electric field-induced destabilization and surface modulation of Aβ42 fibrils in molecular simulations: theoretical implications for direct current stimulation in Alzheimer's disease [0.03%]
分子模拟的电场诱导Aβ42纤维不稳定性及表面调节：阿尔茨海默病直流刺激的理论含义
Fran Bačić Toplek,Natale Vincenzo Maiorana,Matteo Guidetti et al.
Fran Bačić Toplek et al.
Background: The amyloid-β peptide 42 (Aβ42) forms fibrillar aggregates that are a hallmark of Alzheimer's disease. While recent therapeutic strategies targeting Aβ42 fibrils and oligomers have shown promise, safer and ...
A clinical and ECG based score to predict incident atrial fibrillation in cardiac amyloidosis: the Amy-Lyon AF score [0.03%]
基于临床和心电图的预测心脏淀粉样变性患者新发房颤评分：Amy-Lyon AF 评分
Tiphaine Bollon,Antoine Jobbe Duval,Simon Leboube et al.
Tiphaine Bollon et al.
Background: Atrial fibrillation (AF) is common and poorly tolerated in cardiac amyloidosis (CA) patients. No current tool assesses AF risk in this population. ...
Significance of aberrant nerve conduction in hereditary transthyretin amyloidosis [0.03%]
遗传性转甲状腺素蛋白淀粉样变性异常神经传导的意义
Toshihiro Ide,Masaaki Yoshikawa,Kohei Suzuyama et al.
Toshihiro Ide et al.
Background: In hereditary transthyretin (ATTRv) amyloidosis, axonal neuropathy is the main pathologic basis of polyneuropathy. However, whether nerve conduction slowing resembling chronic inflammatory demyelinating polyne...
The CATCH-ATTR study: CArpal Tunnel ligament amyloid-the Clue for early identification of Hereditary or wildtype systemic ATTR amyloidosis? [0.03%]
CATCH-ATTR研究：腕管韧带淀粉样变性是提示遗传或野生型全身性ATTR淀粉样变性的线索吗？
Fabian Aus dem Siepen,Frank Staub,Florian Andre et al.
Fabian Aus dem Siepen et al.
Aims: We sought to investigate the prevalence of Transthyretin amyloid (ATTR) deposits in the carpal ligament of patients undergoing surgery for carpal tunnel syndrome (CTS) and the frequency of concomitant ATTR-cardiomyo...
Yohei Misumi,Toshiya Nomura,Shiori Yamakawa et al.
Yohei Misumi et al.
Background: Acquired transthyretin (ATTR) amyloidosis is increasingly reported among domino liver transplantation (DLT) recipients who receive livers from patients with hereditary variant TTR (ATTRv) amyloidosis. However,...
Prognostic significance of cardiac biomarkers in patients with AL amyloidosis treated with a daratumumab-based regimen [0.03%]
达雷妥尤单抗为基础方案治疗的AL淀粉样变患者心脏生物标志物的预后意义
Taku Kikuchi,Ukyo Kondo,Shotaro Sugita et al.
Taku Kikuchi et al.