Biopersistence of man-made vitreous fibres (MMVF) / synthetic vitreous fibres (SVF): advancing from animal models to acellular testing [0.03%]
人造玻璃纤维(SVF)的生物持久性:从动物模型到无细胞检测的发展
Craig A Poland,Léa Hiéronimus,Denis V Okhrimenko et al.
Craig A Poland et al.
The field of fibre toxicology highlights a significant connection between the physicochemical properties of fibres-such as diameter, length, and durability-and their toxicity when inhaled. Among these properties, durability, particularly in...
Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city [0.03%]
中国城市地铁环境空气颗粒物对健康成人影响的随机对照试验研究
Yuan Sun,Yuting Xiang,Yuwei Chen et al.
Yuan Sun et al.
Background: Subway systems reduce traffic congestion, air pollution, and carbon dioxide emissions in cities but the impacts of subway air pollution on the health of subway users remain obscure. We conducted a randomized c...
Randomized Controlled Trial
Particle and fibre toxicology. 2025 Jul 8;22(1):18. DOI:10.1186/s12989-025-00638-5 2025
Impact of environmental microplastic exposure on HepG2 cells: unraveling proliferation, mitochondrial dynamics and autophagy activation [0.03%]
环境微塑料暴露对HepG2细胞的影响:揭示增殖、线粒体动力学和自噬激活的作用
Hana Najahi,Nicola Alessio,Massimo Venditti et al.
Hana Najahi et al.
The rise of microplastic (MPs) pollution presents a pressing environmental issue, raising concerns about its potential health impacts on human populations. Given the critical role of the liver in detoxification and metabolism, understanding...
Immune consequences of exposure to β-pinene oxidation aerosols: adult versus gestational murine models [0.03%]
β-.pinene氧化气溶胶暴露的免疫效应:成人与孕期小鼠模型比较研究
Muriel Pichavant,Madjid Djouina,Gwenola Kervoaze et al.
Muriel Pichavant et al.
Background: While studies demonstrating the adverse effects of air pollution on human health are accumulating, studies on secondary organic aerosol (SOA) are scarce. However, SOA accounts for a significant portion of airb...
Comparative Study
Particle and fibre toxicology. 2025 May 30;22(1):16. DOI:10.1186/s12989-025-00631-y 2025
Hazard screening of colloidal silica nanomaterials with varying degrees of silane surface functionalization: a safe-by-design case study [0.03%]
不同硅烷改性程度的胶体二氧化硅纳米材料的危害筛查:以安全设计为案例的研究
Nienke Ruijter,Ilaria Zanoni,Daniel Persson et al.
Nienke Ruijter et al.
Background: The Safe and Sustainable by Design (SSbD) concept facilitates the design of safer and more sustainable chemicals and materials and is a crucial approach towards reaching the goals set out in the European Green...
Acute health effects of ambient air pollution including ultrafine particles in a semi-experimental setting in young, healthy individuals [0.03%]
基于半实验设计的研究年轻健康人群呼吸系统急性效应的队列研究
Elisabeth Folwarczny,Felix Forster,Rudolf A Jörres et al.
Elisabeth Folwarczny et al.
Background: Multiple effects of ultrafine particles (UFP) on human subjects are known but there is less knowledge of how relative exposure levels between ultrafine and fine particles as typically encountered in large citi...
Randomized Controlled Trial
Particle and fibre toxicology. 2025 May 23;22(1):14. DOI:10.1186/s12989-025-00628-7 2025
Polystyrene nanoplastics exposure induces cognitive impairment in mice via induction of oxidative stress and ERK/MAPK-mediated neuronal cuproptosis [0.03%]
聚苯乙烯纳米塑料通过诱导氧化应激和ERK / MAPK介导的神经元铜死亡导致小鼠认知障碍
Yinuo Chen,Yiyang Nan,Lang Xu et al.
Yinuo Chen et al.
Background: Recent studies emphasize the significance of copper dyshomeostasis in neurodegenerative diseases, such as Alzheimer's and Parkinson's, thereby highlighting the role of copper in neurotoxicity. Cuproptosis, a n...
Correction: Central IKKβ Inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes [0.03%]
纠正:中央IKKβ抑制防止空气污染引起的外周炎症和II型糖尿病的加重
Cuiqing Liu,Laura K Fonken,Aixia Wang et al.
Cuiqing Liu et al.
Published Erratum
Particle and fibre toxicology. 2025 May 20;22(1):12. DOI:10.1186/s12989-025-00630-z 2025
Investigating the impact of the dispersion protocol on the physico-chemical identity and toxicity of nanomaterials: a review of the literature with focus on TiO2 particles [0.03%]
分散协议对纳米材料的理化性质和毒性的影响研究:以TiO2粒子为例文献回顾
Andrew McCormack,Vicki Stone,James McQuat et al.
Andrew McCormack et al.
Particles often require dispersion in aqueous media to allow assessment of their hazard profile. The approach used to disperse particles is not consistent in the published literature, with approaches including stirring, vortexing, shaking o...
Propionic acid/FBP1 is involved in polystyrene nanoplastic-induced cardiac injury via the gut-heart axis [0.03%]
丁酸/FBP1通过肠道-心脏轴参与聚苯乙烯纳米塑料诱导的心脏损伤
Huiwen Kang,Danyang Huang,Wei Zhang et al.
Huiwen Kang et al.
Background: Micro-/nanoplastics (MNPLs) are widely found in the environment and have toxic effects on various organs and systems. However, the role of the gut-cardiac axis in cardiotoxicity induced by MNPLs has not yet be...