Microplastics are associated with elevated atherosclerotic risk and increased vascular complexity in acute coronary syndrome patients [0.03%]
微塑料与急性冠脉综合征患者的动脉粥样硬化风险增加和血管复杂性升高有关
Yunxiao Yang,Feng Zhang,Zhili Jiang et al.
Yunxiao Yang et al.
Background: Microplastics, widely present in the environment, are implicated in disease pathogenesis through oxidative stress and immune modulation. Prevailing research, primarily based on animal and cell studies, falls s...
Biodistribution of cerium dioxide and titanium dioxide nanomaterials in rats after single and repeated inhalation exposures [0.03%]
单次和反复吸入暴露后纳米二氧化铈和二氧化钛在大鼠体内的分布状况研究
Ilse Gosens,Jordi Minnema,A John F Boere et al.
Ilse Gosens et al.
Background: Physiologically based kinetic models facilitate the safety assessment of inhaled engineered nanomaterials (ENMs). To develop these models, high quality datasets on well-characterized ENMs are needed. However, ...
Multimodal pulmonary clearance kinetics of carbon black nanoparticles deposited in the lungs of rats: the role of alveolar macrophages [0.03%]
肺泡巨噬细胞在沉积于大鼠肺部的炭黑纳米颗粒多模式清除动力学中的作用
Dong-Keun Lee,Gyuri Kim,Muthuchamy Maruthupandy et al.
Dong-Keun Lee et al.
Background: Alveolar macrophages (AMs) have been predicted to affect the pulmonary clearance of nanomaterials; however, their qualitative and quantitative roles are poorly understood. In this study, carbon black nanoparti...
Correction: Combining analytical techniques to assess the translocation of diesel particles across an alveolar tissue barrier in vitro [0.03%]
订正：结合分析技术评估柴油颗粒在体外肺泡组织屏障中的转移情况
Gowsinth Gunasingam,Ruiwen He,Patricia Taladriz-Blanco et al.
Gowsinth Gunasingam et al.
Published Erratum
Particle and fibre toxicology. 2024 Aug 9;21(1):31. DOI:10.1186/s12989-024-00593-7 2024
Protective effect of Cordycepin on blood-testis barrier against pre-puberty polystyrene nanoplastics exposure in male rats [0.03%]
虫草素对青春期前纳米塑料暴露雄性大鼠血睾屏障的保护作用
Ying Hu,Shuyi Jiang,Qiang Zhang et al.
Ying Hu et al.
Plastic pollution is an emerging environmental issue, with microplastics and nanoplastics raising health concerns due to bioaccumulation. This work explored the impact of polystyrene nanoparticle (PS-NPs) exposure during prepuberty on male ...
Investigation of pulmonary inflammatory responses following intratracheal instillation of and inhalation exposure to polypropylene microplastics [0.03%]
经气管内给药和吸入暴露于聚丙烯微塑料后肺部炎症反应的研究
Taisuke Tomonaga,Hidenori Higashi,Hiroto Izumi et al.
Taisuke Tomonaga et al.
Background: Microplastics have been detected in the atmosphere as well as in the ocean, and there is concern about their biological effects in the lungs. We conducted a short-term inhalation exposure and intratracheal ins...
Worse pulmonary function in association with cumulative exposure to nanomaterials. Hints of a mediation effect via pulmonary inflammation [0.03%]
纳米材料累积暴露与肺功能下降及可能的炎症介导效应之间的关联研究
Giulia Squillacioti,Thomas Charreau,Pascal Wild et al.
Giulia Squillacioti et al.
Background: Today, nanomaterials are broadly used in a wide range of industrial applications. Such large utilization and the limited knowledge on to the possible health effects have raised concerns about potential consequ...
Multicenter Study
Particle and fibre toxicology. 2024 Jun 28;21(1):28. DOI:10.1186/s12989-024-00589-3 2024
Systemic immunological responses are dependent on sex and ovarian hormone presence following acute inhaled woodsmoke exposure [0.03%]
急性吸入木烟暴露后系统性免疫反应受性别和卵巢激素影响
Kartika Wardhani,Sydnee Yazzie,Charlotte McVeigh et al.
Kartika Wardhani et al.
Background: Rural regions of the western United States have experienced a noticeable surge in both the frequency and severity of acute wildfire events, which brings significant challenges to both public safety and environ...
Combining analytical techniques to assess the translocation of diesel particles across an alveolar tissue barrier in vitro [0.03%]
联合应用分析技术评估柴油颗粒在体外肺泡组织屏障上的迁移性
Gowsinth Gunasingam,Ruiwen He,Patricia Taladriz-Blanco et al.
Gowsinth Gunasingam et al.
Background: During inhalation, airborne particles such as particulate matter ≤ 2.5 μm (PM2.5), can deposit and accumulate on the alveolar epithelial tissue. In vivo studies have shown that fractions of PM2.5 can cross t...
Determining the toxicological effects of indoor air pollution on both a healthy and an inflammatory-comprised model of the alveolar epithelial barrier in vitro [0.03%]
确定室内空气污染对体外健康和炎症受损的肺泡上皮屏障模型的毒理学影响
Kirsty Meldrum,Stephen J Evans,Michael J Burgum et al.
Kirsty Meldrum et al.
Exposure to indoor air pollutants (IAP) has increased recently, with people spending more time indoors (i.e. homes, offices, schools and transportation). Increased exposures of IAP on a healthy population are poorly understood, and those wi...