Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture [0.03%]
腺苷通过单层培养的绵羊脑脉络丛上皮的转运受限于核苷转运蛋白分布不均一以及胞内酶促降解
Zoran B Redzic,Aleksandra J Isakovic,Sonja T Misirlic Dencic et al.
Zoran B Redzic et al.
Background: Efflux transport of adenosine across the choroid plexus (CP) epithelium might contribute to the homeostasis of this neuromodulator in the extracellular fluids of the brain. The aim of this study was to explore...
Cerebrospinal fluid supports viability and proliferation of cortical cells in vitro, mirroring in vivo development [0.03%]
脑脊液支持皮层细胞的存活和增殖，类似于体内的发育过程
Jaleel A Miyan,Mahjiub Zendah,Farhad Mashayekhi et al.
Jaleel A Miyan et al.
Background: The central nervous system develops around a fluid filled compartment. Recently, attention has turned to the potential role of the fluid (cerebrospinal fluid, CSF) in the developmental process. In particular, ...
Clinical and neuropathological evolution of the hydrocephalus developed by the mutant mouse hyh [0.03%]
突变型小鼠hyh所引起脑积水的临床和神经病理学进展
Federico Bátiz,Patricia Páez,Antonio J Jiménez et al.
Federico Bátiz et al.
The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses [0.03%]
抗HIV药物替诺福韦(PMPA)在脑、脑脊液及脉络丛中的分布
Christy Anthonypillai,Julie E Gibbs,Sarah A Thomas
Christy Anthonypillai
Background: Tenofovir disoproxil fumarate, a prodrug of the nucleotide reverse transcriptase inhibitor, tenofovir (9-[9(R)-2-(phosphonomethoxy)propyl]adenine; PMPA), was recently approved for use in the combination therap...
Dimensions of the posterior fossa in patients symptomatic for Chiari I malformation but without cerebellar tonsillar descent [0.03%]
影像学无小脑扁桃体下疝入椎管的Chiari畸形I型患者后颅窝径线测量值分析
Raymond F Sekula Jr,Peter J Jannetta,Kenneth F Casey et al.
Raymond F Sekula Jr et al.
Background: Chiari I malformation (CMI) is diagnosed by rigid radiographic criteria along with appropriate clinical symptomatology. The aim of this study was to investigate the dimensions of the posterior cranial fossa in...
Memory and selective learning in children with spina bifida-myelomeningocele and shunted hydrocephalus: a preliminary study [0.03%]
Behroze Vachha,Richard C Adams
Behroze Vachha
Background: Selective learning is the ability to select items of relevance from among less important items. Limited evidence exists regarding the efficiency with which children with spina bifida-myelomeningocele and shunt...
Characterization of cytoskeletal and junctional proteins expressed by cells cultured from human arachnoid granulation tissue [0.03%]
人蛛网膜颗粒组织培养细胞的骨架和连接蛋白表达特征分析
David W Holman,Deborah M Grzybowski,Bhavya C Mehta et al.
David W Holman et al.
Background: The arachnoid granulations (AGs) are projections of the arachnoid membrane into the dural venous sinuses. They function, along with the extracranial lymphatics, to circulate the cerebrospinal fluid (CSF) to th...
The circumventricular organs participate in the immunopathogenesis of experimental autoimmune encephalomyelitis [0.03%]
circumventricular器官参与实验性自身免疫性脑脊髓炎的免疫病理发生学
Martina Schulz,Britta Engelhardt
Martina Schulz
Background: During inflammatory conditions of the central nervous system (CNS), such as in multiple sclerosis or in its animal model, experimental autoimmune encephalomyelitis (EAE), immune cells migrate from the blood st...
Yanming F Wang,Judith K Gwathmey,Guorong Zhang et al.
Yanming F Wang et al.
Background: The central nervous system (CNS) is extremely vulnerable to ischemic injury. The details underlying this susceptibility are not completely understood. Since the CNS is surrounded by cerebrospinal fluid (CSF) t...
Integration of the subarachnoid space and lymphatics: is it time to embrace a new concept of cerebrospinal fluid absorption? [0.03%]
蛛网膜下腔和淋巴系统的整合：是时候接受脑脊液吸收的新概念了吗？
Lena Koh,Andrei Zakharov,Miles Johnston
Lena Koh
In most tissues and organs, the lymphatic circulation is responsible for the removal of interstitial protein and fluid but the parenchyma of the brain and spinal cord is devoid of lymphatic vessels. On the other hand, the literature is fill...