The Utility of Molecular Tumor Profiling for Patients With Advanced or Rare Cancer in a Regional Australian Setting [0.03%]
分子肿瘤谱分析在区域性澳大利亚晚期或罕见癌症患者中的应用价值研究
Natalie Chilko,Ortis Estacio,Christopher Steer et al.
Natalie Chilko et al.
Aim: Molecular tumor profiling (MTP) aims to link biomarker targets to corresponding treatments, usually via clinical trials. The usefulness of offering MTP for patients in a regional/rural setting is unknown, including a...
Role of EpCAM-Positive Exosomes in Ovarian Cancer: MiRNA Signatures of Chemoresistance and Disease Progression [0.03%]
卵巢癌中EpCAM阳性外泌体的作用:化疗耐药和疾病进展的miRNA特征
Samruddhi Ranmale,Pavan Kumar,Hemant Tongaonkar et al.
Samruddhi Ranmale et al.
Aim: Ovarian cancer (OC) is a complex disease with challenges such as delayed diagnosis and development of chemoresistance. Exosomes play a crucial role in intercellular communication within the tumor microenvironment and...
Global, Regional, and National DALY and Mortality Burden of Nasopharyngeal Cancer, 1990-2021 [0.03%]
1990年至2021年全球、区域和国家鼻咽癌疾病负担(DALYs和死亡数)
Qian Jiang,Yaosen Shao
Qian Jiang
Objectives: This study quantifies global nasopharyngeal cancer (NPC) mortality and disability-adjusted life years (DALYs) across socio-demographic index (SDI) groups from 1990 to 2021 using Global Burden of Disease Study ...
Real-World Survival Outcomes in EGFR-Mutant Advanced NSCLC Treated With EGFR TKIs: Insights From a Single-Center Clinical Data Warehouse Analysis in South Korea [0.03%]
基于韩国单中心临床数据仓库分析的EGFR突变型晚期NSCLC患者使用EGFR-TKIs治疗后的实际生存结果
Bomi Kim,Sunghoon Kang,Iksoo Huh et al.
Bomi Kim et al.
Purpose: This study aims to evaluate real-world survival outcomes of patients with epidermal growth factor receptor (EGFR)-mutant advanced non-small cell lung cancer (NSCLC) by the generation of EGFR tyrosine kinase inhib...
Prolonged Survival in Anaplastic Thyroid Cancer: Insights From Multi-Modal Treatment [0.03%]
侵袭性甲状腺癌的长期生存:多模式治疗的启示
Bella Nguyen,Richard Gauci,Connull Leslie et al.
Bella Nguyen et al.
Aims: Anaplastic thyroid cancer (ATC) is a rare and aggressive malignancy with limited treatment options and a poor prognosis. This study evaluates the outcomes of patients with locally advanced or metastatic ATC treated ...
Prognostic Significance of Deubiquitinase OTUD7B in NK/T-Cell Lymphoma [0.03%]
去泛素化酶OTUD7B在NK/T细胞淋巴瘤的预后价值
Yizhen Liu,Shujuan Wen,Zuguang Xia et al.
Yizhen Liu et al.
Aim: OTUD7B (ovarian tumor domain-containing 7B) is a deubiquitinase that has established prognostic significance in diffuse large B-cell lymphoma and various solid tumors. In our present work, we aimed to explore its rol...
of Asia: Provision of Patient-Centered Care in Oral Cavity Cancer: A Qualitative Study With Patients, Caregivers, and Healthcare Professionals in Five Asia-Pacific Regions [0.03%]
以患者为中心的口腔癌护理提供:五个亚太地区的定性研究(患者、照护者和医护人员的观点)
Edwin Pun Hui,Puma Sundaresan,Hye Ryun Kim et al.
Edwin Pun Hui et al.
Aim: Locoregionally advanced oral cavity squamous cell carcinoma (LA-OCSCC) imposes a high disease burden, significantly affecting patients' quality of life. We aimed to identify unmet needs and challenges faced by patien...
Romario Nguyen,Fatema Safri,Ankur Sharma et al.
Romario Nguyen et al.
Aim: This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC research, relative to ...
Avelumab First-Line Maintenance for Advanced Urothelial Carcinoma: Real-World Results From an Early Access Program in Malaysia [0.03%]
马来西亚阿维鲁单抗晚期尿路上皮癌一线维持治疗早期通道计划的疗效分析
Fuad Bin Ismail,Mohamed Ibrahim Abdul Wahid,Muthukkumaran Thiagarajan et al.
Fuad Bin Ismail et al.
Aim: Avelumab first-line (1L) maintenance was approved for treatment of advanced urothelial carcinoma (UC) based on results from the JAVELIN Bladder 100 Phase 3 trial. We report real-world data from an early access progra...