Oncological Care Needs of People With Mental Illness: A Single Institution Experience in Australia [0.03%]
精神疾病患者肿瘤护理需求：澳大利亚单个机构的经验
Hui-Ling Yeoh,Wei Hong,Cherelynn Holmes et al.
Hui-Ling Yeoh et al.
Introduction: This retrospective cohort study evaluated the oncological care of people with psychiatric conditions at an outer metropolitan center to audit for clinical disparities in comparison to people without psychiat...
Development and Evaluation of a PEGylated Lyophilized Nanoliposomal Formulation of Nilotinib for Enhanced Solubility, Intestinal Permeation, and In Vitro Anticancer Activity [0.03%]
一种尼洛替尼聚乙二醇脂质体冻干粉纳米制剂的开发与评估：增强溶解性、肠道通透性和体外抗癌活性
Dilpreet Singh,Amritpal Singh,Harinder Singh
Dilpreet Singh
Nilotinib, a potent BCR-ABL tyrosine kinase inhibitor, suffers from poor aqueous solubility, limited dissolution, and inadequate intestinal permeability, thereby restricting its oral bioavailability and broader therapeutic applicability in ...
Trastuzumab Deruxtecan for HER2-Low Metastatic Breast Cancer: Practical Considerations for Medical Oncologists and Pathologists in Australia [0.03%]
低HER2阳性转移性乳腺癌使用德喜曲妥单抗治疗：澳大利亚医学肿瘤学专家与病理学专家的诊疗考量
Andrew Redfern,Elgene Lim,Sunil Lakhani et al.
Andrew Redfern et al.
Trastuzumab deruxtecan (T-DXd) is a third-generation, HER2-targeting antibody-drug conjugate that has been shown to significantly prolong overall survival, compared with standard chemotherapy, when used to treat patients who have "HER2-low"...
Treatment Efficacy, Chemoradiotherapy Benefits, and Survival Disparities by Histology in Primary Mediastinal Germ Cell Tumors: 15-Year Results of a Single-Center Cohort Study [0.03%]
初发纵隔生殖细胞肿瘤的治疗疗效、同期放化疗获益及病理类型差异：单中心队列研究15年结果
Di Wu,Ziran Zhang,Jun Nie et al.
Di Wu et al.
Aim: Primary mediastinal germ cell tumors (PMGCTs), a rare subset of extragonadal GCTs, exhibit heterogeneous prognoses depending on histological subtype. Limited prospective clinical studies exist due to their rarity. Th...
Extracranial, Extragonadal Germ Cell Tumors: A Multicenter Australian Case Series [0.03%]
颅外性副中肾小管来源的生殖细胞肿瘤：一项澳大利亚多中心病例系列研究
Kar Ven Cavan Chow,Ciara Conduit,Sophie O&#x;Haire et al.
Kar Ven Cavan Chow et al.
Aim: To describe the treatment pattern and outcomes for patients with extracranial, extragonadal germ cell tumors (EGCTs). Methods: We ...
Managing Skin Side Effects Associated With Oncology Treatments: Asian Perspective on Use of Dermocosmetics [0.03%]
皮肤科化妆品在肿瘤治疗相关性皮肤病管理中的应用——亚洲视角
Meng Pan,Jianguo Sun,Makoto Kawashima et al.
Meng Pan et al.
Skin adverse events (AEs) frequently accompany all types of anticancer treatments. The type and course of these skin AEs with different cancer treatments have been described and may be considered to generally have a similar pattern in diffe...
Immune Checkpoint Activity and Prognostic Roles of TNFRSF8, CD160, and TNFSF9 in Primary and Brain Metastatic NSCLC [0.03%]
免疫检查点活化及TNFRSF8、CD160和TNFSF9在原发性及脑转移性NSCLC中的预后作用
Sun-Jiang Liu,Man Gu,Shi-Cun Li et al.
Sun-Jiang Liu et al.
Here, we utilized advanced bioinformatics approaches alongside experimental validation to identify key prognostic biomarkers and potential immune checkpoint inhibitors (ICIs) in non-small cell lung cancer (NSCLC). Our findings highlight dis...
Identification of Gastric Cancer Subtypes Based on Neutrophil Extracellular Trap Related Genes [0.03%]
基于中性粒细胞胞外陷阱相关基因的胃癌亚型识别
Heng Zhai,Sen Lei,Saili Liu et al.
Heng Zhai et al.
Objective: This study aimed to classify patients with gastric cancer (GC) based on neutrophil extracellular trap (NET)-related gene expression and to develop a prognostic risk score model. ...
Larotrectinib in Adjuvant and First-Line Treatment for Metastatic NTRK Fusion Colon Cancer [0.03%]
larotrectinib治疗NTRK融合转移性结直肠癌的术后和一线治疗效果
Alexander Y Volkov,Andrey L Pylev,Anna A Zhandarova et al.
Alexander Y Volkov et al.
We report an 83-year-old woman with severe concomitant pathology who underwent surgery for colon cancer, with recurrent bleeding from the tumor, and subcompensated intestinal stenosis. After right-sided hemicolectomy with regional lymph nod...
Mechanism of Astragalus Polysaccharides Regulating Ferroptosis and Inhibiting Malignant Progression of Ovarian Cancer Cells [0.03%]
黄芪多糖调控卵巢癌细胞铁死亡的机制及其抗恶性进展作用
Caihong Li,Youzhen Luo,Qin Wang et al.
Caihong Li et al.
Objective: Ovarian cancer (OC) is the most prevalent cause of death among gynecologic malignancies. Astragalus polysaccharides (APS) possess antitumor activity in OC. We explored the mechanism of APS regulating ferroptosi...