Prognostic Factors of Coronavirus Disease 2019 In-hospital Mortality in Cancer Patients: A Retrospective Cohort Study in Taiwan [0.03%]
台湾癌症患者新型冠状病毒肺炎住院死亡预后因素：一项回顾性队列研究
Jing-Gu Jiang,Shih-Chiang Lin,Jia-Hao Zhang et al.
Jing-Gu Jiang et al.
Aim: The coronavirus disease 2019 (COVID-19) pandemic has significantly strained global healthcare systems. Cancer patients are particularly vulnerable to adverse outcomes from COVID-19 infection. The aim of this study is...
Whole Brain Radiotherapy Versus Stereotactic Radiosurgery in Breast Cancer Patients With Brain Metastases-A Phase 3 Open Label Randomized Study [0.03%]
乳腺癌脑转移患者全脑放疗与立体定向放射外科治疗的III期开放随机研究
Budhi Singh Yadav,Porva Vias,Ngangom Robert et al.
Budhi Singh Yadav et al.
Background: Patients with brain metastases can be treated with whole-brain radiotherapy (WBRT) or stereotactic radiosurgery (SRS). There are no randomized study comparing WBRT with SRS in patients with brain metastases fr...
Feasibility of Clinically Prioritized Colorectal Cancer Quality Indicators With a New South Wales Population-Based Linked Dataset [0.03%]
基于新南威尔士州人口的临床优先结直肠癌质量指标的可行性研究
Candice Donnelly,Puma Sundaresan,James Toh et al.
Candice Donnelly et al.
Aim: To determine the feasibility of using population-based linked data to measure an Australian multidisciplinary set of 26 colorectal cancer (CRC) quality indicators. ...
Does Limited-Margin Radiotherapy Change the Recurrence Pattern and Survival of Patients With IDH-Wild-Type Glioblastoma? Analysis and Validation of a Different Approach [0.03%]
IDH野生型胶质母细胞瘤的限Margin放射治疗会改变患者的复发模式和生存率吗？不同方法的分析与验证
Volkan Semiz,Oguz Cetinayak,Barbaros Aydın et al.
Volkan Semiz et al.
Purpose: We aimed to analyze our radiotherapy protocol by evaluating its effect on recurrence patterns and survival outcomes. Methods: ...
USP44, ZNF454, and GPRC5B ctDNA Methylation Markers in Breast Cancer: Limited Clinical Relevance for Disease Monitoring and Tumor Characteristics [0.03%]
乳腺癌中USP44、ZNF454和GPRC5B的ctDNA甲基化标志物：对疾病监测和肿瘤特征的临床意义有限
Young Ju Jeong,Chang-Ho Jeon,Hoon Kyu Oh et al.
Young Ju Jeong et al.
Purpose: This study aimed to identify breast cancer-specific circulating tumor DNA (ctDNA) methylation markers that correspond to tissue DNA methylation. ...
Hematological Markers Predict Immune-Related Adverse Events in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Treated With Pembrolizumab [0.03%]
血液学标志物可预测派姆单抗治疗复发或转移性头颈部鳞癌所致免疫相关不良反应
Takashi Matsuki,Takuro Okada,Chihiro Fushimi et al.
Takashi Matsuki et al.
Background: In patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN), the correlation between hematological markers and treatment outcomes has been established. However, their pred...
Safety and Efficacy Assessment of Trastuzumab Emtansine in Indian Patients With Human Epidermal Growth Factor Receptor 2-Positive Unresectable Locally Advanced or Metastatic Breast Cancer Previously Treated With Trastuzumab and a Taxane: An Open-Label, Single-Arm, Phase IV Study [0.03%]
一项开放性、单组、多中心的Ⅳ期研究：在印度不可手术局部晚期或转移性且既往接受曲妥珠单抗和紫衫烷治疗的HER2阳性乳腺癌患者中评估T-DM1的安全性和疗效
Sudeep Gupta,Manish Singhal,Shona Nag et al.
Sudeep Gupta et al.
Introduction: Trastuzumab emtansine (T-DM1), an antibody-drug conjugate, targets tumor cells overexpressing human epidermal growth factor receptor 2 (HER2). This single-arm, phase IV study assessed the safety and efficacy...
Papillary Tumors of the Pineal Region (PTPR) in Pediatric Population: A Case Report and Literature Review [0.03%]
儿童松果体区乳头状肿瘤（PTPR）一例并文献复习
Beril Balci Topuz,Serra Kamer,Tugce Bozkurt Vardar et al.
Beril Balci Topuz et al.
Papillary tumors of the pineal region (PTPR) are rare central nervous system neoplasms, with a limited number of pediatric cases reported in the literature. Their optimal management remains unclear due to their unpredictable biological beha...
Purified Cucurbitacin D Leads to Alterations of Apoptotic and Autophagic Genes Expression in MDA-MB-468 and MCF-7 Human Breast Cancer Cells [0.03%]
纯化的瓜尔尼亭D可引起人乳腺癌MDA-MB-468和MCF-7细胞中凋亡及自噬基因表达的改变
Elham Zeinali,Seyed Jalal Zargar,Najmeh Mozdoori
Elham Zeinali
Aim: The use of plant-derived drugs in cancer therapy is widely considered in the treatment of different malignancies including breast cancer. Cucurbitacin D (CuD) is able to induce apoptosis in cancerous cells through di...