Hierarchy of nanoparticles toxicity factors significance as extracted from NanoCommons knowledge base: influence of compound, cell line and particle size on cell viability [0.03%]
基于NanoCommons知识库的纳米粒子毒性因素分级及其对细胞存活率的影响:化合物、细胞系和颗粒尺寸的作用
Michal Macko,František Božek,Diana Kmeťková et al.
Michal Macko et al.
The objective of the paper was to conduct a thorough statistical meta-analysis of a publicly available database by examining cell membrane damage (CMD), mitochondrial membrane potential (MMP), nuclear size (NS), nuclear intensity (NI), and ...
Meta-Analysis
Nanotoxicology. 2025 Sep;19(6):553-574. DOI:10.1080/17435390.2025.2555307 2025
Toxicity assessment of SiO2 nanoparticles on developmental and reproductive traits in Drosophila melanogaster [0.03%]
纳米SiO2颗粒对果蝇发育和生殖特征毒性的评价
Junyue Wang,Yang Jiang,Yán Wāng
Junyue Wang
Silicon dioxide nanoparticles (SiO2 NPs) are widely utilized in industrial and biomedical applications owing to their unique physicochemical properties; however, their potential biological effects require comprehensive evaluation. In this s...
Evaluating the toxicity of PEGylated multiwalled carbon nanotubes in zebrafish embryos: insights for biomedical and environmental safety [0.03%]
聚乙二醇修饰的多壁碳纳米管在斑马鱼胚胎中的毒性评估:生物医药及环境安全性的见解
Nikita Gurphale,Mujahidkhan A Pathan,Kriti Kumari et al.
Nikita Gurphale et al.
Polyethylene glycol-Multiwalled carbon nanotubes (PEG-MWCNTs) hold significant potential for biomedical applications, including diagnostics and controlled drug delivery. However, their toxicity allied to the synthesis process remains a crit...
Multimodal approach to nanoparticle toxicity assessment (conceptual framework for in vitro to in vivo extrapolation) [0.03%]
用于体内外推的纳米粒子毒性评估的多模式方法(概念框架)
Vitaly Goranov,Ivan Siutsou,Alexander Makhaniok et al.
Vitaly Goranov et al.
This study proposes a novel multimodal framework for assessing the time-dependent toxicity of iron oxide nanoparticles (SPIONs), aiming to improve in vitro to in vivo extrapolation (IVIVE). The framework integrates experimental data from Ca...
Silver ion toxicity in commercial colloidal silver: molecular insights from high-content imaging in Huh-7 cells [0.03%]
纳米银产品中银离子的毒性:基于Huh-7细胞高内涵成像的分子机制研究
Bruno L Menna,Mila Simić,Ljubica Tasic et al.
Bruno L Menna et al.
Colloidal silver is marketed as a dietary supplement, despite lacking essential mineral properties, scientific health benefits and potential toxicity. Therefore, we aimed to evaluate the effects of two commercially available colloidal silve...
A meta-analysis and systematic review on the association between air pollution and chronic liver diseases [0.03%]
空气污染与慢性肝病相关性的meta分析和系统评价
Sibo Gao,Li Tian,Yao Zeng et al.
Sibo Gao et al.
Background and aims: Air pollution represents the second most significant global health burden, and existing epidemiological studies have reported that air pollution is harmful to the liver. To comprehensively understand ...
Exploring the effect of short-term exposure to non-functionalized polystyrene nanoparticles on selected chromatin determinants in human immune cells and plasmid DNA integrity [0.03%]
短链未 functionalized 聚苯乙烯纳米颗粒对人类免疫细胞中某些染色质决定因素和质粒DNA完整性的影响研究
Kinga Malinowska,Kateryna Tarhonska,Karolina Górecka et al.
Kinga Malinowska et al.
The effect of non-functionalized polystyrene nanoparticles (PS-NPs) with diameters of 29, 44, and 72 nm on plasmid DNA integrity and the expression of genes involved in the architecture of chromatin was investigated in human peripheral bloo...
The protective effect of sodium selenite against silver nanoparticles induced oxidative stress and autophagy in cardiomyocytes is associated with AMPK/mTOR signaling pathway [0.03%]
亚硒酸钠通过AMPK/m TOR信号通路对抗银纳米颗粒诱导的心肌细胞氧化应激和自噬的作用研究
Wanrui Ma,Qingping He,P Andy Li et al.
Wanrui Ma et al.
Selenite(Se) is a trace mineral that is essential for cardiac health. This study aims to investigate the beneficial effects of Se on cardiomyocyte damage induced by silver nanoparticles (AgNPs) and to explore the underlying protective mecha...
The inherited story: multigenerational reversible effects of graphene oxide from F1 to F4 generations of Drosophila melanogaster [0.03%]
遗传效应的叙事:多代石墨烯氧化物对果蝇(Drosophila melanogaster)从F1到F4世代的可逆影响
Avnika Singh Anand,Kalyani Verma,Amitabh et al.
Avnika Singh Anand et al.
With advances in the application of graphene oxide (GO), the major hindering factor is its toxicity. It is crucial to understand the immediate effects on the parent generation as well as the long-term multigenerational effects on subsequent...
Understanding the PET micro/nanoplastics as an environmental stressor on pancreatin enzyme: leaching and binding characterization by multi-spectroscopic and molecular docking examination, and the resulting impact on Escherichia coli [0.03%]
PET微/纳米塑料作为环境压力源对胰腺酶的影响:多光谱和分子对接检测的析出与结合特性研究及其对大肠杆菌的影响
Hasan Saygin,Asli Baysal,Batuhan Tilkili et al.
Hasan Saygin et al.
The deformation and leaching of substances from micro/nanoplastics under biotic and abiotic conditions is an important yet often overlooked issues for the environment and human health. Furthermore, their interaction with biomolecules can re...