Death from human cytomegalovirus infection in a girl with congenital thymic dysplasia [0.03%]
人类巨细胞病毒感染致死的一例先天性胸腺发育不良女孩的报告
Yang Liu,Yu Zhu,Weiping Liu et al.
Yang Liu et al.
We report the case of a girl with congenital thymic dysplasia and refractory disseminated Human Cytomegalovirus (CMV) infection diagnosed by autopsy. Additionally, she was diagnosed with T-cell lymphopenia immunodeficiency and received anti...
Case Reports
Virology journal. 2022 Nov 8;19(1):179. DOI:10.1186/s12985-022-01915-x 2022
Whole-genome sequence analysis reveals the circulation of multiple SARS-CoV-2 variants of concern in Nairobi and neighboring counties, Kenya between March and July 2021 [0.03%]
全基因组序列分析揭示了肯尼亚奈洛比及其周边地区2021年3月至7月期间多个值得关注的SARS-CoV-2变异株的传播情况
Samoel Ashimosi Khamadi,Silvanos Opanda,Samwel Lifumo Symekher et al.
Samoel Ashimosi Khamadi et al.
The emergence and rapid spread of SARS-CoV-2 variants of concern (VOC) have been linked to new waves of COVID-19 epidemics occurring in different regions of the world. The VOC have acquired adaptive mutations that have enhanced virus transm...
Establishment of early diagnosis models for cervical precancerous lesions using large-scale cervical cancer screening datasets [0.03%]
基于大规模宫颈癌筛查数据集的宫颈癌前病变早期诊断模型的建立及相关研究
Bo Meng,Guibin Li,Zhengyu Zeng et al.
Bo Meng et al.
Background: Human papilloma virus (HPV) DNA test was applied in cervical cancer screening as an effective cancer prevention strategy. The viral load of HPV generated by different assays attracted increasing attention on i...
Tripartite motif-containing protein 46 accelerates influenza A H7N9 virus infection by promoting K48-linked ubiquitination of TBK1 [0.03%]
三重基序包含蛋白46通过促进TBK1的K48链接泛素化来加速甲型H7N9流感病毒的感染
Wei Su,Xian-Tian Lin,Shuai Zhao et al.
Wei Su et al.
Background: Avian influenza A H7N9 emerged in 2013, threatening public health and causing acute respiratory distress syndrome, and even death, in the human population. However, the underlying mechanism by which H7N9 virus...
A Δ42PD1 fusion-expressing DNA vaccine elicits enhanced adaptive immune response to HIV-1: the key role of TLR4 [0.03%]
TLR4在HIV-1Δ42PD1融合表达型DNA疫苗诱导的适应性免疫应答中的关键作用
Lin Cheng,Xian Tang,Yun He et al.
Lin Cheng et al.
Since its discovery in the 1990s, the DNA vaccine has been of great interest because of its ability to elicit both humoral and cellular immune responses while showing relative advantages regarding producibility, stability and storage. Howev...
Prevalence and pathology of equine parvovirus-hepatitis in racehorses from New York racetracks [0.03%]
纽约赛马场赛马的马肝炎病毒-parvo病毒感染流行率和病理学研究
Mason C Jager,Joy E Tomlinson,Caitlin E Henry et al.
Mason C Jager et al.
Background: Theiler's disease, a.k.a. equine serum hepatitis, is a devastating, highly fatal disease of horses. Equine parvovirus-hepatitis (EqPV-H) has been identified as the likely cause of this disease. While the incid...
Human adenoviral (HAdV) chronic arthritis expands the infectious spectrum of primary agammaglobulinemia [0.03%]
人腺病毒(HAdV)慢性关节炎扩大了一次性免疫球蛋白缺乏症的感染谱系
Grégoire Martin de Frémont,Maud Salmona,François Maillet et al.
Grégoire Martin de Frémont et al.
Inborn errors of immunity (IEI) are a heterogeneous entity with an increasing number of late diagnoses. Besides infections, inflammatory manifestations are a growing part of the clinical landscape of IEI. These complications are of unknown ...
Adeno-associated virus infection and its impact in human health: an overview [0.03%]
腺相关病毒的感染及其对人类健康的影响：概述
Thaís B Sant&#x;Anna,Natalia M Araujo
Thaís B Sant&#x;Anna
Discovered as a contaminant of adenovirus stocks in the 1960s, adeno-associated virus (AAV) is a mono-stranded DNA virus that depends on helper factors to replicate. Even though AAV is endemic in the human population (35-80%), it is remarka...
Correction: comparing the expression levels of tripartite motif containing 28 in mild and severe COVID-19 infection [0.03%]
订正：比较轻度和重度COVID-19感染中三聚体基序含28蛋白的表达量
Rezvan Tavakoli,Pooneh Rahimi,Mojtaba Hamidi-Fard et al.
Rezvan Tavakoli et al.
Published Erratum
Virology journal. 2022 Oct 31;19(1):171. DOI:10.1186/s12985-022-01903-1 2022
A high-throughput screening assay to identify inhibitory antibodies targeting alphavirus release [0.03%]
一种高效筛选实验以识别靶向 alphavirus 释放的抑制性抗体
Anushka Ramjag,Sergej Cutrone,Kai Lu et al.
Anushka Ramjag et al.
Background: Several studies have demonstrated neutralizing antibodies to be highly effective against alphavirus infection in animal models, both prophylactically and remedially. In most studies, neutralizing antibodies ha...