A comprehensive review of COVID-19 symptoms and treatments in the setting of autoimmune diseases [0.03%]
自身免疫疾病背景下COVID-19症状和治疗的综合回顾
Zahra Hamidi,Shaghaiegh Jabraeili-Siahroud,Yalda Taati-Alamdari et al.
Zahra Hamidi et al.
After the first reporting of the index case of Severe Acute Respiratory Syndrome (SARS)-CoV-2-associated disease at the end of December 2019, the virus spread quickly throughout the world, prompting the WHO on 11 March 2020 to declare the d...
Mechanism of autophagy induced by activation of the AMPK/ERK/mTOR signaling pathway after TRIM22-mediated DENV-2 infection of HUVECs [0.03%]
TRIM22介导的DENV-2感染HUVECs后通过AMPK/ERK/mTOR信号通路激活诱导自噬的作用机制研究
Ning Wu,Xiaoqin Gou,Pan Hu et al.
Ning Wu et al.
Background: Dengue virus type 2 (DENV-2) was used to infect primary human umbilical vein endothelial cells (HUVECs) to examine autophagy induced by activation of the adenosine monophosphate-activated protein kinase (AMPK)...
Highly efficacious and safe neutralizing DNA aptamer of SARS-CoV-2 as an emerging therapy for COVID-19 disease [0.03%]
用于治疗COVID-19疾病的高效安全的SARS-CoV-2中和DNA适体
Mohamad Ammar Ayass,Trivendra Tripathi,Natalya Griko et al.
Mohamad Ammar Ayass et al.
Background: The paucity of SARS-CoV-2-specific virulence factors has greatly hampered the therapeutic management of patients with COVID-19 disease. Although available vaccines and approved therapies have shown tremendous ...
Suppression of porcine hemagglutinating encephalomyelitis virus replication by resveratrol [0.03%]
白藜芦醇对猪溶血性脑脊髓炎病毒复制的抑制作用
Yuzhu Liu,Deguang Song,Xueli Liu et al.
Yuzhu Liu et al.
Background: Porcine hemagglutinating encephalomyelitis virus (PHEV), a member of the genus Betacoronavirus, is the causative agent of neurological disease in pigs. No effective therapeutics are currently available for PHE...
Transmission dynamics of human herpesvirus 6A, 6B and 7 from whole genome sequences of families [0.03%]
家庭全基因序列揭示的人类疱疹病毒6A、6B和7的传播动力学
Brianna S Chrisman,Chloe He,Jae-Yoon Jung et al.
Brianna S Chrisman et al.
While hundreds of thousands of human whole genome sequences (WGS) have been collected in the effort to better understand genetic determinants of disease, these whole genome sequences have less frequently been used to study another major det...
Suppressive effects of pterostilbene on human cytomegalovirus (HCMV) infection and HCMV-induced cellular senescence [0.03%]
pterostilbene对人巨细胞病毒(HCMV)感染及HCMV诱导的细胞衰老的抑制作用
Sanying Wang,Xuqiang Zhou,Xinyue He et al.
Sanying Wang et al.
Background: Human cytomegalovirus (HCMV), a member of the β-herpesvirus family, causes the establishment of a latent infection that persists throughout the life of the host and can be reactivated when immunity is weakene...
Adaptive immune responses and cytokine immune profiles in humans following prime and boost vaccination with the SARS-CoV-2 CoronaVac vaccine [0.03%]
SARS-CoV-2 Coronavac疫苗初次和加强接种后人体的适应性免疫反应及细胞因子免疫谱分析
Chan Wang,Songhao Yang,Liangwei Duan et al.
Chan Wang et al.
Background: Adaptive immune response has been thought to play a key role in SARS-CoV-2 infection. The role of B cells, CD4+T, and CD8+T cells are different in vaccine-induced immune response, thus it is imperative to expl...
ADAR1p110 promotes Enterovirus D68 replication through its deaminase domain and inhibition of PKR pathway [0.03%]
ADAR1p110通过脱氨酶结构域促进Enterovirus D68复制及对PKR通路的抑制
Kehan Zhang,Siyuan Wang,Tingting Chen et al.
Kehan Zhang et al.
Background: Severe respiratory and neurological diseases caused by human enterovirus D68 (EV-D68) pose a serious threat to public health, and there are currently no effective drugs and vaccines. Adenosine deaminase acting...
Sandra Niendorf,Andreas Mas Marques,Claus-Thomas Bock et al.
Sandra Niendorf et al.
Aim of this study was to investigate the molecular diversity of human astroviruses (HAstV) in Germany. A follow-up study was performed with human stool samples collected in 2018-2019, which were genotyped retrospectively. A total of 2645 st...
Mohammad Abavisani,Karim Rahimian,Bahar Mahdavi et al.
Mohammad Abavisani et al.
Background: Emergence of new variants mainly variants of concerns (VOC) is caused by mutations in main structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, we aimed to investigat...