Gargle sample is an effective option in a novel fully automated molecular point-of-care test for influenza: a multicenter study [0.03%]
漱液样本在新型全自动化分子POCT流感检测中有效性的多中心研究
Norihito Kaku,Tomohito Urabe,Tetsuya Iida et al.
Norihito Kaku et al.
Background: We conducted a multicenter study to evaluate the performance of a novel fully automated molecular point-of-care test using transcription-reverse transcription concerted reaction that can detect influenza A and...
Multicenter Study
Virology journal. 2023 Mar 3;20(1):41. DOI:10.1186/s12985-023-01993-5 2023
RT-PCR-based assessment of the SD Bioline Rota/Adeno Antigen-based test in infants with and without diarrhea [0.03%]
基于RT-PCR评估SD Bioline Rota/Adeno抗原检测在腹泻婴幼儿与非腹泻婴幼儿中的应用价值
Gédéon Prince Manouana,Paul Alvyn Nguema-Moure,Alexandru Tomazatos et al.
Gédéon Prince Manouana et al.
Background: Rotavirus A (RVA) infections remain a major cause of severe acute diarrhea affecting children worldwide. To date, rapid diagnostic tests (RDT) are widely used to detect RVA. However, paediatricians question wh...
Oligonucleotide usage in coronavirus genomes mimics that in exon regions in host genomes [0.03%]
冠状病毒基因组中寡核苷酸的使用类似于宿主基因组中的外显子区域
Yuki Iwasaki,Takashi Abe,Toshimichi Ikemura
Yuki Iwasaki
Background: Viruses use various host factors for their growth, and efficient growth requires efficient use of these factors. Our previous study revealed that the occurrence frequency of oligonucleotides in the influenza v...
VLPs containing stalk domain and ectodomain of matrix protein 2 of influenza induce protection in mice [0.03%]
含有流感病毒基质蛋白2 stalk结构域和胞外区的囊泡状颗粒可诱导小鼠产生保护力
Lili Shi,Ying Long,Yanyan Zhu et al.
Lili Shi et al.
Background: As a result of antigenic drift, current influenza vaccines provide limited protection against circulating influenza viruses, and vaccines with broad cross protection are urgently needed. Hemagglutinin stalk do...
Mohadese Hashem Boroojerdi,Tariq Al Jabry,Seyed Mohamad Javad Mirarefin et al.
Mohadese Hashem Boroojerdi et al.
Since December 2019, various types of strategies have been applied due to the emergent need to investigate the biology and pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to discover a functional treatment. Diff...
The presence of human respiratory syncytial virus in the cerebrospinal fluid of a child with Anti-N-methyl-D-aspartate receptor encephalitis of unknown trigger [0.03%]
抗原触发不明的N-甲基-D-天冬氨酸受体脑炎儿童脑脊液中的人呼吸道合胞病毒的存在
Siyan Yu,Ying Hua,Jun Qian et al.
Siyan Yu et al.
Background: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an important type of brain inflammation caused by autoantibody. As one of the primary agents responsible for respiratory tract infection, the hum...
Case Reports
Virology journal. 2023 Feb 24;20(1):34. DOI:10.1186/s12985-023-01997-1 2023
Intragenomic rearrangements involving 5'-untranslated region segments in SARS-CoV-2, other betacoronaviruses, and alphacoronaviruses [0.03%]
SARS-CoV-2及其他贝塔冠状病毒和阿尔法冠状病毒中涉及5'非翻译区片段的同源重组事件
Roberto Patarca,William A Haseltine
Roberto Patarca
Background: Variation of the betacoronavirus SARS-CoV-2 has been the bane of COVID-19 control. Documented variation includes point mutations, deletions, insertions, and recombination among closely or distantly related cor...
Assessment of the clinical and analytical performance of the Aptima SARS-CoV-2 assay using the VALCOR protocol [0.03%]
VALCOR协议下评估AptimaSARS-CoV-2检测试剂盒的临床及分析性能
Sharonjit K Dhillon,Cindy Simoens,Lize Cuypers et al.
Sharonjit K Dhillon et al.
Background: The COVID-19 pandemic highlighted the importance of diagnostic testing against curbing the spread of SARS-CoV-2. The urgent need and scale for diagnostic tools resulted in manufacturers of SARS-CoV-2 assays re...
Analysis of 3.5 million SARS-CoV-2 sequences reveals unique mutational trends with consistent nucleotide and codon frequencies [0.03%]
对350万份SARS-CoV-2基因序列的分析揭示了独特的突变趋势及其一致的核苷酸和密码子频率
Sarah E Fumagalli,Nigam H Padhiar,Douglas Meyer et al.
Sarah E Fumagalli et al.
Background: Since the onset of the SARS-CoV-2 pandemic, bioinformatic analyses have been performed to understand the nucleotide and synonymous codon usage features and mutational patterns of the virus. However, comparativ...
The detectable anti-interferon-γ autoantibodies in COVID-19 patients may be associated with disease severity [0.03%]
COVID-19患者中可检测到的抗干扰素-γ自身抗体可能与疾病严重程度相关
Po-Ku Chen,Kai-Jieh Yeo,Shih-Hsin Chang et al.
Po-Ku Chen et al.
Background: Neutralizing anti-interferon (IFN)-γ autoantibodies are linked to adult-onset immunodeficiency and opportunistic infections. Methods: ...