A quadruple fluorescence quantitative PCR method for the identification of wild strains of african swine fever and gene-deficient strains [0.03%]
一种用于鉴别野毒株和基因缺失毒株的非洲猪瘟四重荧光定量PCR方法
Xuezhi Zuo,Guorui Peng,Yingju Xia et al.
Xuezhi Zuo et al.
Background: Originating in Africa, African swine fever (ASF) was introduced to China in 2018. This acute and highly virulent infectious disease affects domestic pigs. The World Organization for Animal Health has listed it...
Microglia play an important role in PRV infection-induced immune responses of the central nervous system [0.03%]
微胶质细胞在PRV感染诱导的中枢神经系统免疫应答中起重要作用
Xiuxiu Sun,Xinxin Jin,Xi Liu et al.
Xiuxiu Sun et al.
Pseudorabies virus (PRV) can infect multiple hosts and lead to fatal encephalitis. There is a significant increase in the number of microglia in the brain of animals infected with PRV. However, whether and how microglia contribute to centra...
Research article antibody induction and immune response in nasal cavity by third dose of SARS-CoV-2 mRNA vaccination [0.03%]
关于第三次SARS-CoV-2mRNA疫苗接种诱导抗体和鼻腔免疫反应的研究文章
Aya Ishizaka,Michiko Koga,Taketoshi Mizutani et al.
Aya Ishizaka et al.
Background: The mucosa serves as the first defence against pathogens and facilitates the surveillance and elimination of symbiotic bacteria by mucosal immunity. Recently, the mRNA vaccine against SARS-CoV-2 has been demon...
Screening and identification of emodin as an EBV DNase inhibitor to prevent its biological functions [0.03%]
筛选并鉴定出大黄素作为EB病毒DNase抑制剂以防止其生物学功能
Chung-Chun Wu,Mei-Shu Chen,Ting-Ying Lee et al.
Chung-Chun Wu et al.
Background: The Epstein-Barr virus (EBV) is a prevalent oncovirus associated with a variety of human illnesses. BGLF5, an EBV DNase with alkaline nuclease (AN) activity, plays important roles in the viral life cycle and p...
HIV-1 molecular transmission network and drug resistance in Chongqing, China, among men who have sex with men (2018-2021) [0.03%]
中国重庆 MSM 中 HIV-1 分子传播网络及耐药性（2018-2021）
Tianyu Tan,Chongyang Bai,Rongrong Lu et al.
Tianyu Tan et al.
Background: Over the past few years, HIV transmission among men who have sex with men (MSM) in China has increased significantly. Chongqing, located in the southwest of China, has the highest prevalence of HIV among MSM i...
Circulation of multiple hepatitis B virus genotypes in individual pregnant women seeking antenatal care in northern Ghana [0.03%]
几内亚北部寻求产前护理的孕妇中多重乙型肝炎病毒基因型的传播
Nsoh Godwin Anabire,Osbourne Quaye,Gideon Kofi Helegbe
Nsoh Godwin Anabire
Background: Identification and monitoring of HBV genotype variations is important, since that can help forecast the likelihood of developing serious liver disease and how well patients respond to antiviral medication. Giv...
Human papillomavirus spectrum of HPV-infected women in Nigeria: an analysis by next-generation sequencing and type-specific PCR [0.03%]
尼日利亚HPV感染女性的人乳头瘤病毒谱系分析：基于新一代测序和型别特异性PCR技术的研究
Ngozi Dom-Chima,Yakubu Abubakar Ajang,Chinyere Ifeoma Dom-Chima et al.
Ngozi Dom-Chima et al.
Background: Human papillomavirus (HPV) infection and cervical cancer are leading health problems and causes of death in many parts of the world. There are ~ 200 HPV types that can infect humans. This study aims to underst...
Vaccinia virus induces endoplasmic reticulum stress and activates unfolded protein responses through the ATF6α transcription factor [0.03%]
痘病毒诱导内质网应激并通过活化转录因子ATF6α引发未折叠蛋白反应
Thiago Lima Leão,Karine Lima Lourenço,Cid de Oliveira Queiroz et al.
Thiago Lima Leão et al.
Background: Cell responses to different stress inducers are efficient mechanisms that prevent and fight the accumulation of harmful macromolecules in the cells and also reinforce the defenses of the host against pathogens...
Harsh,Pratima Tripathi
Harsh
The recent epidemics and pandemics caused by different viruses such as SARS-CoV-2, monkey pox, H1N1, ebola virus etc. have been a cause of mass destruction in the human race, the biggest decline slope in the global economy and mental trauma...
Patch-clamp studies and cell viability assays suggest a distinct site for viroporin inhibitors on the E protein of SARS-CoV-2 [0.03%]
补孔钳制研究和细胞活力测定表明SARS-CoV-2的E蛋白上病毒离子通道抑制剂的独特作用位点
Ulrike Breitinger,Christine Adel Sedky,Heinrich Sticht et al.
Ulrike Breitinger et al.
Background: SARS-CoV-2 has caused a worldwide pandemic since December 2019 and the search for pharmaceutical targets against COVID-19 remains an important challenge. Here, we studied the envelope protein E of SARS-CoV and...