Oncolytic activity of a coxsackievirus B3 strain in patient-derived cervical squamous cell carcinoma organoids and synergistic effect with paclitaxel [0.03%]
一种柯萨奇病毒B3株在患者来源的宫颈鳞状细胞癌类器官中的溶瘤活性及其与紫杉醇的协同作用
Yanzhen Lin,Nanyi Liu,Chuanlai Yang et al.
Yanzhen Lin et al.
Background: Cervical squamous cell carcinoma (CSCC) is a prevalent gynecological malignancy worldwide. Current treatments for CSCC can impact fertility and cause long-term complications, underscoring the need for new ther...
The impact of hepatitis B surface antigen seroconversion on the durability of functional cure induced by pegylated interferon alpha treatment [0.03%]
贝那鲁肽联合利拉鲁肽与利拉鲁肽单药治疗对中国2型糖尿病患者血糖控制的影响：一项随机、双盲、平行分组、头对头对照的临床试验
Wencong Zhang,Jia Chen,Wenjin Sun et al.
Wencong Zhang et al.
Background: Hepatitis B surface antigen (HBsAg) loss is regarded as a pivotal criterion for assessing functional cure in patients diagnosed chronic hepatitis B (CHB). We conducted the research to investigate the real-worl...
Lineage and sublineage analysis of human papillomavirus type 58 in iranian women [0.03%]
伊朗妇女人乳头瘤病毒58型系和亚系分析
Mohammad Shabanpour,Parvin Jalali-Alhosseini,Zabihollah Shoja et al.
Mohammad Shabanpour et al.
Background: Variant analysis of distinct HPV types is important from different aspects including epidemiology, pathogenicity, and evolution. Methods: ...
Genomic analysis of an acute gastroenteritis outbreak caused by rotavirus C in Hebei, China [0.03%]
中国河北一次由轮状病毒C型引起的急性胃肠炎暴发的基因组分析
Kaiying Wang,Yun Wang,Lang Yang et al.
Kaiying Wang et al.
Rotavirus group C is an important cause of sporadic cases and outbreaks of gastroenteritis worldwide. Whole-Genome sequences of human rotavirus C (RVC) in public databases are limited. We performed genome sequencing to analyze a RVC outbrea...
Comparative pathogenicity of influenza virus-induced pneumonia mouse model following intranasal and aerosolized intratracheal inoculation [0.03%]
不同给药方式的流感病毒对小鼠肺炎发病的影响及致病性研究
Xiu-Yu Jin,Hui-Ying Yang,Guang-Yu Zhao et al.
Xiu-Yu Jin et al.
Background: Infection of mice with mouse-adapted strains of influenza virus has been widely used to establish mouse pneumonia models. Intranasal inoculation is the traditional route for constructing an influenza virus-ind...
Comparative Study
Virology journal. 2024 Oct 1;21(1):240. DOI:10.1186/s12985-024-02516-6 2024
Replication kinetics of pathogenic Eurasian orthohantaviruses in human mesangial cells [0.03%]
致病性欧亚正汉坦病毒在人系膜细胞中的复制动力学研究
Lukas Boegelein,Pamela Schreiber,Alexandra Philipp et al.
Lukas Boegelein et al.
Background: Eurasian pathogenic orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by acute kidney injury (AKI). The virulence of orthohantaviruses varies enormously and direct infection of...
Advances in nucleic acid aptamer-based detection of respiratory virus and bacteria: a mini review [0.03%]
核酸适配体呼吸病毒和细菌检测研究进展-mini review
Rui-Min Feng,Ye Liu,Zhi-Qiang Liu et al.
Rui-Min Feng et al.
Respiratory pathogens infecting the human respiratory system are characterized by their diversity, high infectivity, rapid transmission, and acute onset. Traditional detection methods are time-consuming, have low sensitivity, and lack speci...
Intracellular delivery of antiviral shRNA using penetratin-based complexes effectively inhibits respiratory syncytial virus replication and host cell apoptosis [0.03%]
利用基于穿透肽的复合物介导抗病毒shRNA高效传递抑制呼吸道合胞病毒复制和宿主细胞凋亡
Faezeh Faghirabadi,Haniyeh Abuei,Mohammad Hossein Malekzadeh et al.
Faezeh Faghirabadi et al.
Background: Cell-penetrating peptides (CPPs) are effective for delivering therapeutic molecules with minimal toxicity. This study focuses on the use of penetratin, a well-characterized CPP, to deliver a DNA vector encodin...
Frequency and genotyping of group A rotavirus among Egyptian children with acute gastroenteritis: a hospital-based cross-sectional study [0.03%]
急性胃肠炎患儿轮状病毒A组感染的流行率和基因型分布：基于医院的横断面研究
Ensaf A Azzazy,Rania M Amer,Ghada Mohammed Abdellatif et al.
Ensaf A Azzazy et al.
Background: This hospital-based cross-sectional study aims to investigate the epidemiologic and clinical characteristics of rotavirus group A (RVA) infection among children with acute gastroenteritis and to detect the mos...
Convalescent anti-SARS-CoV-2 plasma for the treatment of patients with COVID-19: a retrospective study RESCOVID-19 [0.03%]
COVID-19患者的恢复期血浆治疗：RESCOVID-19回顾性研究
Miloš Bohoněk,Jan Máca,Jiří Sagan et al.
Miloš Bohoněk et al.
Purpose: Convalescent plasma (CP) collected from people who recovered from COVID-19 became a rapidly available treatment modality in numerous countries, including the Czech Republic. The aims of our study were to evaluate...
Observational Study
Virology journal. 2024 Sep 30;21(1):239. DOI:10.1186/s12985-024-02475-y 2024