Endogenous ZAP is associated with altered Zika virus infection phenotype [0.03%]
内源性ZAP与寨卡病毒感染表型改变有关
Nguyen Phuong Khanh Le,Prince Pal Singh,Ahmad Jawad Sabir et al.
Nguyen Phuong Khanh Le et al.
The zinc finger antiviral protein 1 (ZAP) has broad antiviral activity. ZAP is an interferon (IFN)-stimulated gene, which itself may enhance type I IFN antiviral response. In a previous study, Zika virus was identified as ZAP-resistant and ...
Characterization and complete genome sequence of highly lytic phage active against methicillin-resistant Staphylococcus aureus (MRSA) isolated from Egypt [0.03%]
从埃及分离的高裂解性耐甲氧西林金黄色葡萄球菌(MRSA)病毒的特性及全基因组序列测定
Abeer K Abd El-Tawab,B A Othman,A Sharaf et al.
Abeer K Abd El-Tawab et al.
Background: Methicillin-Resistant Staphylococcus aureus (MRSA) is one of the most resistant bacteria to antibiotics. S. aureus is an important, widespread pathogen that can cause a variety of infectious diseases in humans...
Characterization of phage HZY2308 against Acinetobacter baumannii and identification of phage-resistant bacteria [0.03%]
HZY2308溶源菌的特性分析及芽孢杆菌耐噬菌体突变株的筛选鉴定
Ruilin Wang,Xiaojuan You,Xinwei Liu et al.
Ruilin Wang et al.
Background: Acinetobacter baumannii (AB) is a notable cause of hospital-acquired infections, with carbapenem-resistant Acinetobacter baumannii (CRAB) classified as a high-priority critical pathogen. Bacteriophage therapy ...
Different immunogens and prime-boost vaccination strategies affect the efficacy of recombinant candidate vaccines against pathogenic orthopoxviruses [0.03%]
不同的免疫原和强化免疫策略会影响重组候选疫苗针对致病性正痘病毒的效力
Antonia Radaelli,Carlo Zanotto,Chiara Brambilla et al.
Antonia Radaelli et al.
Although not as lethal as variola virus (VARV), the cause of smallpox, monkeypox virus (MPXV) represents a threat to public health, with important infection rates and mortality in several African countries and signs of spreading worldwide. ...
Pilot-scale process development for recombinant adeno-associated virus (rAAV) production based on high-density Sf9 cell culture [0.03%]
基于Sf9高密度培养的重组腺相关病毒(rAAV)生产工艺的放大开发
Xinran Li,Jieyi Gu,Haoquan Wu et al.
Xinran Li et al.
Background: In recent years, gene therapy drugs have been widely marketed, and their effectiveness and potential have been confirmed. Thus, increasing their production on an industrial scale is critical. Recombinant adeno...
The causal association between COVID-19 and ischemic stroke: a mendelian randomization study [0.03%]
关于COVID-19与缺血性卒中的因果关联:一项孟德尔随机化研究
Zhaojie Zhang,Jie Hua,Liang Chen
Zhaojie Zhang
Background: Current observational data indicates that ischemic stroke (IS) affects a significant proportion of people with COVID-19. The current study sought to evaluate the causal relationship between COVID-19 and IS. ...
Detection and molecular characterization of lumpy skin disease and bovine papular stomatitis viruses in lumpy skin disease-suspected outbreaks in Tanzania [0.03%]
坦桑尼亚疑似痘皮病暴发点的痘皮病和牛乳头状口炎病毒的检测及分子特征分析
Fredy T Makoga,Jelly S Changa,Irene K Meki et al.
Fredy T Makoga et al.
Background: Lumpy Skin Disease (LSD) is endemic in sub-Saharan countries and is currently a global threat to the cattle industry. Information on the circulating Capripoxvirus lumpyskinpox, formerly known as Lumpy Skin Dis...
Zhong Liping,Yu Sheng,Wu Yinhang et al.
Zhong Liping et al.
Background: Researchers gradually focus on the relationship between phage and cancer. Objective: To summarize the research hotspots and...
Comparative study of neutralizing antibodies titers in response to different types of COVID-19 vaccines among a group of egyptian healthcare workers [0.03%]
埃及医务人员接种不同类型的新冠疫苗后中和抗体滴度的比较研究
Sara Maher,Nihal M El Assaly,Doaa Mamdouh Aly et al.
Sara Maher et al.
Background: Defining the protective thresholds against the severe-acute-respiratory-syndrome-related corona virus-2 pandemic is a crucial challenge. To reduce the risks of severe disease, hospitalization, and death, vario...
Comparative Study
Virology journal. 2024 Nov 5;21(1):277. DOI:10.1186/s12985-024-02546-0 2024
A novel neutralizing monoclonal antibody recognizes a linear antigenic epitope of the spike protein of swine acute diarrhoea syndrome coronavirus [0.03%]
一种新的中和单克隆抗体识别猪急性腹泻综合征冠状病毒刺突蛋白线性抗原表位
Lin Zhang,Hui-Zhen Liu,Yuexiao Lian et al.
Lin Zhang et al.
Swine acute diarrhoea syndrome coronavirus (SADS-CoV) causes vomiting, severe diarrhoea and death in newborn piglets. The spike (S) protein plays a crucial role in promoting virus invasion and inducing neutralizing antibody production. In t...